5T2T

Crystal structure of Lymphocytic choriomeningitis mammarenavirus endonuclease bound to compound L742001

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue MN A 201

Chain	Residue
A	ASP88
A	CYS102
A	MN202
A	0N8203
A	HOH340
A	HOH342

---

site_id	AC2
Number of Residues	6
Details	binding site for residue MN A 202

Chain	Residue
A	HOH308
A	HOH313
A	HOH360
A	ASP88
A	MN201
A	0N8203

---

site_id	AC3
Number of Residues	15
Details	binding site for residue 0N8 A 203

Chain	Residue
A	LYS43
A	ARG47
A	LEU84
A	ASP88
A	CYS102
A	LYS114
A	MN201
A	MN202
A	GOL204
A	HOH308
A	HOH313
A	HOH340
A	HOH360
B	GLU181
B	TYR182

---

site_id	AC4
Number of Residues	7
Details	binding site for residue GOL A 204

Chain	Residue
A	LYS114
A	GLU117
A	0N8203
A	HOH350
A	HOH385
B	GLU179
B	GLU181

---

site_id	AC5
Number of Residues	5
Details	binding site for residue GOL B 201

Chain	Residue
A	ARG8
A	LEU12
B	ARG8
B	LEU12
B	LEU29

---

site_id	AC6
Number of Residues	2
Details	binding site for residue CL B 202

Chain	Residue
B	LYS91
B	NA204

---

site_id	AC7
Number of Residues	2
Details	binding site for residue CL B 203

Chain	Residue
B	GLU153
B	NA205

---

site_id	AC8
Number of Residues	2
Details	binding site for residue NA B 204

Chain	Residue
B	CL202
B	HOH394

---

site_id	AC9
Number of Residues	3
Details	binding site for residue NA B 205

Chain	Residue
B	GLU153
B	CL203
B	HOH393

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04086","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04086","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---