3JSB

Crystal structure of the N-terminal domain of the Lymphocytic Choriomeningitis Virus L protein

Summary for 3JSB

DescriptorRNA-directed RNA polymerase (2 entities in total)
Functional Keywordsviral protein, vizier, structural genomics, marseilles structural genomics program @ afmb, msgp, nucleotide-binding, nucleotidyltransferase, rna replication, rna-directed rna polymerase, transferase, virion, rna binding protein
Biological sourceLymphocytic choriomeningitis virus (LCMV)
Cellular locationVirion P14240
Total number of polymer chains2
Total molecular weight47444.34
Authors
Morin, B.,Jamal, S.,Ferron, F.P.,Coutard, B.,Bricogne, G.,Canard, B.,Vonrhein, C.,Marseilles Structural Genomics Program @ AFMB (MSGP) (deposition date: 2009-09-10, release date: 2010-09-15, Last modification date: 2012-02-15)
Primary citation
Morin, B.,Coutard, B.,Lelke, M.,Ferron, F.P.,Kerber, R.,Jamal, S.,Frangeul, A.,Baronti, C.,Charrel, R.,de Lamballerie, X.,Vonrhein, C.,Lescar, J.,Bricogne, G.,Gunther, S.,Canard, B.
The N-terminal domain of the arenavirus L protein is an RNA endonuclease essential in mRNA transcription
Plos Pathog., 6:e1001038-e1001038, 2010
PubMed: 20862324 (PDB entries with the same primary citation)
DOI: 10.1371/journal.ppat.1001038
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.13 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22520.6%9.4%7.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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Molmil generated image of 3jsb
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Molmil generated image of 3jsb
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More Biological unit images

Molmil generated image of 3jsb
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Molmil generated image of 3jsb
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Molmil generated image of 3jsb
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (3jsb.pdb1.gz [128.85 KB])
Coordinate files for Biological unit (3jsb.pdb2.gz [141.45 KB])