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PDB: 2 results

8BCR
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BU of 8bcr by Molmil
DENV3 Methyltransferase in complexed with AT-9010 and SAH
Descriptor: Genome polyprotein, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Gauffre, P, Fattorini, V, Canard, B, Ferron, F.
Deposit date:2022-10-17
Release date:2023-03-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:AT-752 targets multiple sites and activities on the Dengue virus replication enzyme NS5.
Antiviral Res., 212, 2023
7ED5
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BU of 7ed5 by Molmil
A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase
Descriptor: MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ...
Authors:Shannon, A, Fattorini, V, Sama, B, Selisko, B, Feracci, M, Falcou, C, Gauffre, P, El Kazzi, P, Delpal, A, Decroly, E, Alvarez, K, Eydoux, C, Guillemot, J.-C, Moussa, A, Good, S, Colla, P, Lin, K, Sommadossi, J.-P, Zhu, Y.X, Yan, X.D, Shi, H, Ferron, F, Canard, B.
Deposit date:2021-03-15
Release date:2022-02-16
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase.
Nat Commun, 13, 2022

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