Author results

3E00
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INTACT PPAR GAMMA - RXR ALPHA NUCLEAR RECEPTOR COMPLEX ON DNA BOUND WITH GW9662, 9-CIS RETINOIC ACID AND NCOA2 PEPTIDE
分子名称:Retinoic acid receptor RXR-alpha, Peroxisome proliferator-activated receptor gamma, DNA (5'-D(*DCP*DAP*DAP*DAP*DCP*DTP*DAP*DGP*DGP*DTP*DCP*DAP*DAP*DAP*DGP*DGP*DTP*DCP*DAP*DG)-3'), ...
著者Chandra, V., Huang, P., Hamuro, Y., Raghuram, S., Wang, Y., Burris, T.P., Rastinejad, F.
登録日2008-07-30
公開日2008-10-28
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA.
Nature, 456, 2008
3GO6
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CRYSTAL STRUCTURE OF M. TUBERCULOSIS RIBOKINASE (RV2436) IN COMPLEX WITH RIBOSE AND AMP-PNP
分子名称:RIBOKINASE RBSK, alpha-D-ribofuranose, MAGNESIUM ION, ...
著者Masters, E.I., Sun, Y., Wang, Y., Parker, W.B., Li, R.
登録日2009-03-18
公開日2010-03-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Crystal structure and biochemical characterization of M.tuberculosis ribokinase (Rv2436)
To be Published
3GO7
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CRYSTAL STRUCTURE OF M. TUBERCULOSIS RIBOKINASE (RV2436) IN COMPLEX WITH RIBOSE
分子名称:RIBOKINASE RBSK, alpha-D-ribofuranose, MAGNESIUM ION
著者Masters, E.I., Sun, Y., Wang, Y., Parker, W.B., Li, R.
登録日2009-03-18
公開日2010-03-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure and biochemical characterization of M.tuberculosis ribokinase (Rv2436)
To be Published
3HHS
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CRYSTAL STRUCTURE OF MANDUCA SEXTA PROPHENOLOXIDASE
分子名称:Phenoloxidase subunit 2, Phenoloxidase subunit 1, COPPER (II) ION
著者Li, Y., Wang, Y., Jiang, H., Deng, J.
登録日2009-05-17
公開日2009-09-29
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Crystal structure of Manduca sexta prophenoloxidase provides insights into the mechanism of type 3 copper enzymes.
Proc.Natl.Acad.Sci.USA, 106, 2009
3RJY
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CRYSTAL STRUCTURE OF HYPERTHERMOPHILIC ENDO-BETA-1,4-GLUCANASE IN COMPLEX WITH SUBSTRATE
分子名称:Endoglucanase FnCel5A, alpha-D-glucopyranose, PHOSPHATE ION
著者Zheng, B., Yang, W., Zhao, X., Wang, Y., Lou, Z., Rao, Z., Feng, Y.
登録日2011-04-15
公開日2012-02-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of hyperthermophilic Endo-beta-1,4-glucanase: Implications for catalytic mechanism and thermostability.
J.Biol.Chem., 287, 2012
4AUA
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LIGANDED X-RAY CRYSTAL STRUCTURE OF CYCLIN DEPENDENT KINASE 6 (CDK6)
分子名称:CYCLIN-DEPENDENT KINASE 6, 1H-benzimidazol-2-yl(1H-pyrrol-2-yl)methanone
著者Cho, Y.S., Angove, H., Brain, C., Chen, C.H.T., Cheng, R., Chopra, R., Chung, K., Congreve, M., Dagostin, C., Davis, D., Feltell, R., Giraldes, J., Hiscock, S., Kim, S., Kovats, S., Lagu, B., Lewry, K., Loo, A., Lu, Y., Luzzio, M., Maniara, W., Mcmenamin, R., Mortenson, P., Benning, R., O'Reilly, M., Rees, D., Shen, J., Smith, T., Wang, Y., Williams, G., Woolford, A., Wrona, W., Xu, M., Yang, F., Howard, S.
登録日2012-05-15
公開日2013-02-06
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Fragment-Based Discovery of 7-Azabenzimidazoles as Potent, Highly Selective, and Orally Active CDK4/6 Inhibitors.
ACS Med Chem Lett, 3, 2012
4GJH
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CRYSTAL STRUCTURE OF THE TRAF DOMAIN OF TRAF5
分子名称:TNF receptor-associated factor 5
著者Zhang, P., Reichardt, A., Liang, H., Wang, Y., Cheng, D., Aliyari, R., Cheng, G., Liu, Y.
登録日2012-08-09
公開日2012-11-28
実験手法X-RAY DIFFRACTION (2.805 Å)
主引用文献Single Amino Acid Substitutions Confer the Antiviral Activity of the TRAF3 Adaptor Protein onto TRAF5
Sci.Signal., 5, 2012
4JKR
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CRYSTAL STRUCTURE OF E. COLI RNA POLYMERASE IN COMPLEX WITH PPGPP
分子名称:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA', ...
著者Zuo, Y., Wang, Y., Steitz, T.A.
登録日2013-03-11
公開日2013-05-15
最終更新日2013-10-23
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献The mechanism of E. coli RNA polymerase regulation by ppGpp is suggested by the structure of their complex.
Mol.Cell, 50, 2013
4NAC
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF P15RS
分子名称:Regulation of nuclear pre-mRNA domain-containing protein 1A
著者Mei, K., Jin, Z., Ren, F., Wang, Y.
登録日2013-10-22
公開日2013-12-11
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献Crystal Structure of the N-terminal Domain of p15RS
To be Published
4NAD
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF CREPT
分子名称:Regulation of nuclear pre-mRNA domain-containing protein 1B
著者Mei, K., Jin, Z., Ren, F., Wang, Y.
登録日2013-10-22
公開日2013-12-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of the C-terminal Domain of CREPT
To be Published
4R0S
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CRYSTAL STRUCTURE OF P. AERUGINOSA TPBA
分子名称:Protein tyrosine phosphatase TpbA, PHOSPHATE ION, GLYCEROL
著者Xu, K., Li, S., Wang, Y., Bartlam, M.
登録日2014-08-01
公開日2015-05-06
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structural and Biochemical Analysis of Tyrosine Phosphatase Related to Biofilm Formation A (TpbA) from the Opportunistic Pathogen Pseudomonas aeruginosa PAO1
PLoS ONE, 10, 2015
4R0T
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CRYSTAL STRUCTURE OF P. AERUGINOSA TPBA (C132S) IN COMPLEX WITH PTYR
分子名称:Protein tyrosine phosphatase TpbA, TYROSINE, PHOSPHATE ION
著者Xu, K., Li, S., Wang, Y., Bartlam, M.
登録日2014-08-01
公開日2015-05-06
実験手法X-RAY DIFFRACTION (2.603 Å)
主引用文献Structural and Biochemical Analysis of Tyrosine Phosphatase Related to Biofilm Formation A (TpbA) from the Opportunistic Pathogen Pseudomonas aeruginosa PAO1
Plos One, 10
5GON
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STRUCTURES OF A BETA-LACTAM BRIDGED ANALOGUE IN COMPLEX WITH TUBULIN
分子名称:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
著者Zhou, L., Liu, Y., Cheng, L., Wang, Y.
登録日2016-07-28
公開日2017-03-22
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Potent Antitumor Activities and Structure Basis of the Chiral beta-Lactam Bridged Analogue of Combretastatin A-4 Binding to Tubulin.
J. Med. Chem., 59, 2016
5H7O
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CRYSTAL STRUCTURE OF DJ-101 IN COMPLEX WITH TUBULIN PROTEIN
分子名称:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
著者Arnst, K., Wang, Y., Hwang, D.-J., Xue, Y., Costello, T., Hamilton, D., Chen, Q., Yang, J., Park, F., Dalton, J.T., Miller, D.D., Li, W.
登録日2016-11-20
公開日2017-12-13
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A Potent, Metabolically Stable Tubulin Inhibitor Targets the Colchicine Binding Site and Overcomes Taxane Resistance.
Cancer Res., 78, 2018
5XG7
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GALECTIN-13/PLACENTAL PROTEIN 13 CRYSTAL STRUCTURE
分子名称:Galactoside-binding soluble lectin 13
著者Su, J.Y., Wang, Y.
登録日2017-04-12
公開日2018-01-31
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Galectin-13, a different prototype galectin, does not bind beta-galacto-sides and forms dimers via intermolecular disulfide bridges between Cys-136 and Cys-138
Sci Rep, 8, 2018
5XHC
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CRYSTAL STRUCTURE OF T2R-TTL-PO10 COMPLEX
分子名称:Tubulin alpha chain, Tubulin beta chain, Stathmin-4, ...
著者Chu, Y., Wang, Y., Yang, J., Li, W.
登録日2017-04-20
公開日2017-10-18
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Synthesis, biological evaluation and X-ray structure of anti-microtubule agents
To Be Published
5XI5
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CRYSTAL STRUCTURE OF T2R-TTL-PO5 COMPLEX
分子名称:Tubulin alpha chain, Tubulin beta chain, Stathmin-4, ...
著者Chu, Y., Wang, Y., Yang, J., Li, W.
登録日2017-04-26
公開日2017-10-18
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Synthesis, biological evaluation and X-ray structure of anti-microtubule agents
To Be Published
5XI7
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CRYSTAL STRUCTURE OF T2R-TTL BOUND WITH PO-7
分子名称:Tubulin alpha chain, Tubulin beta chain, Stathmin-4, ...
著者Chu, Y., Wang, Y., Yang, J., Li, W.
登録日2017-04-26
公開日2017-10-18
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Synthesis, biological evaluation and X-ray structure of anti-microtubule agents
To Be Published
5Z4U
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CRYSTAL STRUCTURE OF T2R-TTL COMPLEX WITH 7A3
分子名称:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
著者Lai, Q., Wang, Y., Yang, J., Yao, Y.
登録日2018-01-14
公開日2019-01-23
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Crystal Structure of T2R-TTL complex with 7a3
To Be Published
6AVS
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COMPLEX STRUCTURE OF JMJD5 AND SYMMETRIC MONOMETHYL-ARGININE (MMA)
分子名称:Lysine-specific demethylase 8, ZINC ION, (2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid
著者Lee, S., Liu, H., Wang, Y., Dai, S., Zhang, G.
登録日2017-09-04
公開日2018-02-28
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7.
Sci Rep, 8, 2018
6AX3
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COMPLEX STRUCTURE OF JMJD5 AND SYMMETRIC DIMETHYL-ARGININE (SDMA)
分子名称:Lysine-specific demethylase 8, N3, N4-DIMETHYLARGININE, ...
著者Lee, S., Liu, H., Wang, Y., Dai, S., Zhang, G.
登録日2017-09-06
公開日2018-02-28
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7.
Sci Rep, 8, 2018
6D88
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TUBULIN-RB3_SLD-TTL IN COMPLEX WITH COMPOUND 13F
分子名称:Tubulin alpha-1B chain, Tubulin beta chain, Stathmin-4, ...
著者Kumar, G., Wang, Y., Li, W., White, S.W.
登録日2018-04-26
公開日2018-09-12
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.853 Å)
主引用文献Structural Modification of the 3,4,5-Trimethoxyphenyl Moiety in the Tubulin Inhibitor VERU-111 Leads to Improved Antiproliferative Activities.
J. Med. Chem., 61, 2018
6IFO
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CRYSTAL STRUCTURE OF ACRIIA2-SPYCAS9-SGRNA TERNARY COMPLEX
分子名称:CRISPR-associated endonuclease Cas9/Csn1, RNA (99-MER), AcrIIA2
著者Liu, L., Wang, Y.
登録日2018-09-20
公開日2019-01-23
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (3.313 Å)
主引用文献Phage AcrIIA2 DNA Mimicry: Structural Basis of the CRISPR and Anti-CRISPR Arms Race.
Mol. Cell, 73, 2019
6JXR
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STRUCTURE OF A PROTEIN
分子名称:T-cell surface glycoprotein CD3 zeta chain, T-cell surface glycoprotein CD3 delta chain, T-cell surface glycoprotein CD3 epsilon chain, ...
著者Dong, D., Zheng, L., Lin, J., Zhu, Y., Li, N., Zhang, B., Xie, S., Zheng, J., Wang, Y., Gao, N., Huang, Z.
登録日2019-04-24
公開日2019-09-11
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of assembly of the human T cell receptor-CD3 complex.
Nature, 573, 2019
6K3Z
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CRYSTAL STRUCTURE OF DCAS9 IN COMPLEX WITH SGRNA AND DNA (TGA PAM)
分子名称:RNA (81-MER), CRISPR-associated endonuclease Cas9, DNA (28-MER), ...
著者Chen, W., Zhang, H., Zhang, Y., Wang, Y., Gan, J., Ji, Q.
登録日2019-05-22
公開日2019-09-25
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease.
Plos Biol., 17, 2019
167327
件を2020-08-05に公開中