5OCH
| The crystal structure of human ABCB8 in an outward-facing state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family B member 8, mitochondrial, ... | Authors: | Faust, B, Pike, A.C.W, Shintre, C.A, Quiqley, A.M, Chu, A, Barr, A, Shrestha, L, Mukhopadhyay, S, Borkowska, O, Chalk, R, Burgess-Brown, N.A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | Deposit date: | 2017-06-30 | Release date: | 2018-07-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | The crystal structure of human ABCB8 in an outward-facing state To Be Published
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3GP0
| Crystal Structure of Human Mitogen Activated Protein Kinase 11 (p38 beta) in complex with Nilotinib | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Mitogen-activated protein kinase 11, ... | Authors: | Filippakopoulos, P, Barr, A, Fedorov, O, Keates, T, Soundararajan, M, Elkins, J, Salah, E, Burgess-Brown, N, Ugochukwu, E, Pike, A.C.W, Muniz, J, Roos, A, Chaikuad, A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-03-20 | Release date: | 2009-04-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of Human Mitogen Activated Protein Kinase 11 (p38 beta) in complex with Nilotinib To be Published
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3GVU
| The crystal structure of human ABL2 in complex with GLEEVEC | Descriptor: | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Tyrosine-protein kinase ABL2 | Authors: | Ugochukwu, E, Salah, E, Barr, A, Mahajan, P, Shrestha, B, Savitsky, P, Chaikuad, A, Filippakopoulos, P, Roos, A, Pike, A.C.W, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-03-31 | Release date: | 2009-04-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The crystal structure of human ABL2 in complex with GLEEVEC To be Published
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3HMI
| The crystal structure of human ABL2 in complex with 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE | Descriptor: | 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE, Tyrosine-protein kinase ABL2 | Authors: | Ugochukwu, E, Salah, E, Barr, A, Mahajan, P, Shrestha, B, Savitsky, P, Chaikuad, A, Allerston, C, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-05-29 | Release date: | 2009-07-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The crystal structure of human ABL2 in complex with 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE To be Published
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4DYL
| F-BAR domain of human FES tyrosine kinase | Descriptor: | Tyrosine-protein kinase Fes/Fps | Authors: | Ugochukwu, E, Salah, E, Elkins, J, Barr, A, Krojer, T, Filippakopoulos, P, Weigelt, J, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2012-02-29 | Release date: | 2012-04-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | F-BAR domain of human FES tyrosine kinase TO BE PUBLISHED
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3OP3
| Crystal Structure of Cell Division Cycle 25C Protein Isoform A from Homo sapiens | Descriptor: | M-phase inducer phosphatase 3, SULFATE ION | Authors: | Kim, Y, Weger, A, Hatzos, C, Savitsky, P, Johansson, C, Ball, L, Barr, A, Vollmar, M, Muniz, J, Weigelt, J, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O, von Delft, F, Knapp, S, Joachimiak, A, Structural Genomics Consortium (SGC) | Deposit date: | 2010-08-31 | Release date: | 2010-09-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Crystal Structure of Cell Division Cycle 25C Protein Isoform A from Homo sapiens TO BE PUBLISHED
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2PQ5
| Crystal structure of Dual specificity protein phosphatase 13 (DUSP13) | Descriptor: | Dual specificity protein phosphatase 13 | Authors: | Ugochukwu, E, Salah, E, Savitsky, P, Barr, A, Pantic, N, Niesen, F, Burgess-Brown, N, Berridge, G, Bunkoczi, G, Uppenberg, J, Pike, A.C.W, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2007-05-01 | Release date: | 2007-05-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of Dual specificity protein phosphatase 13 (DUSP13). To be Published
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2VSW
| The structure of the rhodanese domain of the human dual specificity phosphatase 16 | Descriptor: | DUAL SPECIFICITY PROTEIN PHOSPHATASE 16 | Authors: | Murray, J.W, Barr, A, Pike, A.C.W, Elkins, J, Phillips, C, Wang, J, Savitsky, P, Roos, A, Bishop, S, Wickstroem, M, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Burgess-Brown, N, Pantic, N, Bray, J, von Delft, F, Gileadi, O, Knapp, S. | Deposit date: | 2008-04-30 | Release date: | 2008-07-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Structure of the Rhodanese Domain of the Human Dual Specifity Phosphatase 16 To be Published
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3FME
| Crystal Structure of Human Mitogen-Activated Protein Kinase Kinase 6 (MEK6) Activated Mutant (S207D, T211D) | Descriptor: | Dual specificity mitogen-activated protein kinase kinase 6, STAUROSPORINE | Authors: | Filippakopoulos, P, Barr, A, Pike, A.C.W, Berridge, G, Elkins, J, Fedorov, O, Keates, T, Savitsky, P, Soundararajan, M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2008-12-21 | Release date: | 2009-01-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Crystal Structure of Human Mitogen-Activated Protein Kinase Kinase 6 (MEK6) Activated Mutant (S207D, T211D) To be Published
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1C3N
| CRYSTAL STRUCTURE OF HELIANTHUS TUBEROSUS LECTIN COMPLEXED TO MAN(1-2)MAN | Descriptor: | AGGLUTININ, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose | Authors: | Bourne, Y, Zamboni, V, Barre, A, Peumans, W.J, van Damme, E.J.M, Rouge, P. | Deposit date: | 1999-07-28 | Release date: | 2000-01-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Helianthus tuberosus lectin reveals a widespread scaffold for mannose-binding lectins. Structure Fold.Des., 7, 1999
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1C3K
| CRYSTAL STRUCTURE OF HELIANTHUS TUBEROSUS LECTIN | Descriptor: | AGGLUTININ | Authors: | Bourne, Y, Zamboni, V, Barre, A, Peumans, W.J, van Damme, E.J.M, Rouge, P. | Deposit date: | 1999-07-28 | Release date: | 2000-01-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Helianthus tuberosus lectin reveals a widespread scaffold for mannose-binding lectins. Structure Fold.Des., 7, 1999
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1C3M
| CRYSTAL STRUCTURE OF HELTUBA COMPLEXED TO MAN(1-3)MAN | Descriptor: | AGGLUTININ, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose | Authors: | Bourne, Y, Zamboni, V, Barre, A, Peumans, W.J, van Damme, E.J.M, Rouge, P. | Deposit date: | 1999-07-28 | Release date: | 2000-01-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Helianthus tuberosus lectin reveals a widespread scaffold for mannose-binding lectins. Structure Fold.Des., 7, 1999
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1FNY
| LEGUME LECTIN OF THE BARK OF ROBINIA PSEUDOACACIA. | Descriptor: | BARK AGGLUTININ I,POLYPEPTIDE A, CALCIUM ION | Authors: | Rabijns, A, Verboven, C, Rouge, P, Barre, A, Van Damme, E.J, Peumans, W.J, De Ranter, C.J. | Deposit date: | 2000-08-24 | Release date: | 2001-08-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Structure of a legume lectin from the bark of Robinia pseudoacacia and its complex with N-acetylgalactosamine. Proteins, 44, 2001
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1FNZ
| A bark lectin from robinia pseudoacacia in complex with N-acetylgalactosamine | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, BARK AGGLUTININ I, POLYPEPTIDE A, ... | Authors: | Rabijns, A, Verboven, C, Rouge, P, Barre, A, Van Damme, E.J, Peumans, W.J, De Ranter, C.J. | Deposit date: | 2000-08-24 | Release date: | 2001-08-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure of a legume lectin from the bark of Robinia pseudoacacia and its complex with N-acetylgalactosamine Proteins, 44, 2001
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1JY5
| RNase-related protein from Calystegia sepium | Descriptor: | CalsepRRP | Authors: | Rabijns, A, Verboven, C, Rouge, P, Barre, A, Van Damme, E.J.M, Peumans, W.J, De Ranter, C.J. | Deposit date: | 2001-09-11 | Release date: | 2002-04-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure of an RNase-related protein from Calystegia sepium. Acta Crystallogr.,Sect.D, 58, 2002
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1OUW
| Crystal structure of Calystegia sepium agglutinin | Descriptor: | 1,2-ETHANEDIOL, D-MALATE, IMIDAZOLE, ... | Authors: | Bourne, Y, Roig-Zamboni, V, Barre, A, Peumans, W.J, Astoul, C.H, van Damme, E.J.M, Rouge, P. | Deposit date: | 2003-03-25 | Release date: | 2003-11-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.37 Å) | Cite: | The crystal structure of the Calystegia sepium agglutinin reveals a novel quaternary arrangement of lectin subunits with a beta-prism fold J.Biol.Chem., 279, 2004
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2CYG
| Crystal structure at 1.45- resolution of the major allergen endo-beta-1,3-glucanase of banana as a molecular basis for the latex-fruit syndrome | Descriptor: | beta-1, 3-glucananse | Authors: | Receveur-Brechot, V, Czjzek, M, Barre, A, Roussel, A, Peumans, W.J, Van Damme, E.J.M, Rouge, P. | Deposit date: | 2005-07-07 | Release date: | 2005-11-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal structure at 1.45-A resolution of the major allergen endo-beta-1,3-glucanase of banana as a molecular basis for the latex-fruit syndrome Proteins, 63, 2006
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1KUJ
| Crystal structure of Jacalin complexed with 1-O-methyl-alpha-D-mannose | Descriptor: | JACALIN ALPHA CHAIN, JACALIN BETA CHAIN, methyl alpha-D-mannopyranoside | Authors: | Bourne, Y, Astoul, C.H, Zamboni, V, Peumans, W.J, Menu-Bouaouiche, L, Van Damme, E.J.M, Barre, A, Rouge, P. | Deposit date: | 2002-01-22 | Release date: | 2002-06-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the unusual carbohydrate-binding specificity of jacalin towards galactose and mannose. Biochem.J., 364, 2002
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1KU8
| Crystal structure of Jacalin | Descriptor: | JACALIN ALPHA CHAIN, JACALIN BETA CHAIN | Authors: | Bourne, Y, Astoul, C.H, Zamboni, V, Peumans, W.J, Menu-Bouaouiche, L, Van Damme, E.J.M, Barre, A, Rouge, P. | Deposit date: | 2002-01-21 | Release date: | 2002-06-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural basis for the unusual carbohydrate-binding specificity of jacalin towards galactose and mannose. Biochem.J., 364, 2002
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1XXR
| Structure of a mannose-specific jacalin-related lectin from Morus Nigra in complex with mannose | Descriptor: | ACETIC ACID, GLYCEROL, SULFATE ION, ... | Authors: | Rabijns, A, Barre, A, Van Damme, E.J.M, Peumans, W.J, De Ranter, C.J, Rouge, P. | Deposit date: | 2004-11-08 | Release date: | 2005-10-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose Febs J., 272, 2005
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1Z3Q
| Resolution of the structure of the allergenic and antifungal banana fruit thaumatin-like protein at 1.7A | Descriptor: | 1,2-ETHANEDIOL, Thaumatin-like Protein | Authors: | Leone, P, Menu-Bouaouiche, L, Peumans, W.J, Barre, A, Payan, F, Roussel, A, Van Damme, E.J.M, Rouge, P. | Deposit date: | 2005-03-14 | Release date: | 2006-01-24 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Resolution of the structure of the allergenic and antifungal banana fruit thaumatin-like protein at 1.7-A Biochimie, 88, 2006
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1XXQ
| Structure of a mannose-specific jacalin-related lectin from Morus nigra | Descriptor: | ACETIC ACID, GLYCEROL, SULFATE ION, ... | Authors: | Rabijns, A, Barre, A, Van Damme, E.J.M, Peumans, W.J, De Ranter, C.J, Rouge, P. | Deposit date: | 2004-11-08 | Release date: | 2005-10-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose Febs J., 272, 2005
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5IT6
| Galectin-related protein: an integral member of the network of chicken galectins | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Galectin-related protein, ... | Authors: | Flores-Ibarra, A, Garcia-Caballero, G, Michalak, M, Bovin, N.V, Andre, S, Manning, J.C, Vertesy, S, Ruiz, F.M, Kaltner, H, Kopitz, J, Romero, A, Gabius, H.-J. | Deposit date: | 2016-03-16 | Release date: | 2016-07-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.547 Å) | Cite: | Galectin-related protein: An integral member of the network of chicken galectins 1. From strong sequence conservation of the gene confined to vertebrates to biochemical characteristics of the chicken protein and its crystal structure. Biochim.Biophys.Acta, 1860, 2016
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6FOF
| Crystal structure of a crystallized variant of h-Gal3: Gal-3[NTS/VII-IX] | Descriptor: | Galectin-3,Galectin-3, SULFATE ION, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Romero, A, Flores-Ibarra, A, Medrano, F.J. | Deposit date: | 2018-02-07 | Release date: | 2018-07-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystallization of a human galectin-3 variant with two ordered segments in the shortened N-terminal tail. Sci Rep, 8, 2018
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7MLF
| Crystal Structure of SARS-CoV-2 Main Protease (3CLpro/Mpro) Covalently Bound to Compound C7 | Descriptor: | 3C-like proteinase, N-(4-tert-butylphenyl)-2-chloro-N-[(1R)-2-(cyclohexylamino)-2-oxo-1-(pyridin-3-yl)ethyl]acetamide | Authors: | Sharon, I, Stille, J, Tjutrins, J, Wang, G, Venegas, F.A, Hennecker, C, Rueda, A.M, Miron, C.E, Pinus, S, Labarre, A, Patrascu, M.B, Vlaho, D, Huot, M, Mittermaier, A.K, Moitessier, N, Schmeing, T.M. | Deposit date: | 2021-04-28 | Release date: | 2021-12-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Design, synthesis and in vitro evaluation of novel SARS-CoV-2 3CL pro covalent inhibitors. Eur.J.Med.Chem., 229, 2021
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