1XXQ

Structure of a mannose-specific jacalin-related lectin from Morus nigra

Summary for 1XXQ

Entry DOI	10.2210/pdb1xxq/pdb
Related	1XXR
Descriptor	mannose-binding lectin, ACETIC ACID, GLYCEROL, ... (5 entities in total)
Functional Keywords	tetrameric b-prism fold, jacalin-fold, sugar binding protein
Biological source	Morus nigra
Total number of polymer chains	4
Total formula weight	68788.51
Authors	Rabijns, A.,Barre, A.,Van Damme, E.J.M.,Peumans, W.J.,De Ranter, C.J.,Rouge, P. (deposition date: 2004-11-08, release date: 2005-10-25, Last modification date: 2024-03-13)
Primary citation	Rabijns, A.,Barre, A.,Van Damme, E.J.M.,Peumans, W.J.,De Ranter, C.J.,Rouge, P. Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose Febs J., 272:3725-3732, 2005 Cited by PubMed Abstract: The structures of MornigaM and the MornigaM-mannose complex have been determined at 1.8 A and 2.0 A resolution, respectively. Both structures adopt the typical beta-prism motif found in other jacalin-related lectins and their tetrameric assembly closely resembles that of jacalin. The carbohydrate-binding cavity of MornigaM readily binds mannose. No major structural rearrangements can be observed in MornigaM upon binding of mannose. These results allow corroboration of the structure-function relationships within the small group of Moraceae lectins. PubMed: 16008570 DOI: 10.1111/j.1742-4658.2005.04801.x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation