Author results

6E5C
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SOLUTION NMR STRUCTURE OF A DE NOVO DESIGNED DOUBLE-STRANDED BETA-HELIX
分子名称:De novo beta protein
著者Marcos, E., Chidyausiku, T.M., McShan, A., Evangelidis, T., Nerli, S., Sgourakis, N., Tripsianes, K., Baker, D.
登録日2018-07-19
公開日2018-11-07
最終更新日2018-11-14
実験手法SOLUTION NMR
主引用文献De novo design of a non-local beta-sheet protein with high stability and accuracy.
Nat. Struct. Mol. Biol., 25, 2018
5L33
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED PROTEIN WITH CURVED BETA-SHEET
分子名称:denovo NTF2
著者Oberdorfer, G., Marcos, E., Basanta, B., Chidyausiku, T.M., Sankaran, B., Baker, D.
登録日2016-08-03
公開日2017-01-25
最終更新日2017-02-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
5TPH
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED PROTEIN HOMODIMER WITH CURVED BETA-SHEET
分子名称:de novo NTF2 homodimer, DI(HYDROXYETHYL)ETHER, CHLORIDE ION
著者Basanta, B., Marcos, E., Oberdorfer, G., Chidyausiku, T.M., Sankaran, B., Baker, D.
登録日2016-10-20
公開日2017-01-25
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
5TPJ
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED PROTEIN WITH CURVED BETA-SHEET
分子名称:denovo NTF2
著者Basanta, B., Oberdorfer, G., Marcos, E., Chidyausiku, T.M., Sankaran, B., Baker, D.
登録日2016-10-20
公開日2017-01-25
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (3.101 Å)
主引用文献Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
5TRV
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED PROTEIN WITH CURVED BETA-SHEET
分子名称:denovo NTF2, DI(HYDROXYETHYL)ETHER
著者Basanta, B., Oberdorfer, G., Marcos, E., Chidyausiku, T.M., Sankaran, B., Baker, D.
登録日2016-10-27
公開日2017-01-25
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
5TS4
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED PROTEIN WITH CURVED BETA-SHEET
分子名称:denovo NTF2, DI(HYDROXYETHYL)ETHER
著者Basanta, B., Oberdorfer, G., Chidyausiku, T.M., Marcos, E., Pereira, J.H., Sankaran, B., Zwart, P.H., Baker, D.
登録日2016-10-27
公開日2017-01-25
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (3.005 Å)
主引用文献Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
5U35
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED PROTEIN WITH CURVED BETA-SHEET
分子名称:De novo NTF2 with large cavity, 2-METHOXYETHANOL, CHLORIDE ION, ...
著者Oberdorfer, G., Marcos, E., Basanta, B., Chidyausiku, T.M., Sankaran, B., Zwart, P.H., Baker, D.
登録日2016-12-01
公開日2017-01-25
最終更新日2017-02-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
4R80
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED BETA SHEET PROTEIN, CYSTATIN FOLD, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR486
分子名称:OR486
著者Guan, R., Marcos, E., O'Connell, P., Seetharaman, J., Janjua, H., Xiao, R., Maglaqui, M., Acton, T.B., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
登録日2014-08-29
公開日2014-09-24
実験手法X-RAY DIFFRACTION (2.445 Å)
主引用文献Crystal Structure of an engineered protein with denovo beta sheet design, Northeast Structural Genomics Consortium (NESG) Target OR486
To be Published
6D0T
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DE NOVO DESIGN OF A FLUORESCENCE-ACTIVATING BETA BARREL - BB1
分子名称:BB1
著者Dou, J., Vorobieva, A.A., Sheffler, W., Doyle, L.A., Park, H., Bick, M.J., Mao, B., Foight, G.W., Lee, M., Carter, L., Sankaran, B., Ovchinnikov, S., Marcos, E., Huang, P., Vaughan, J.C., Stoddard, B.L., Baker, D.
登録日2018-04-10
公開日2018-09-19
最終更新日2018-10-17
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
5KPE
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SOLUTION NMR STRUCTURE OF DENOVO BETA SHEET DESIGN PROTEIN, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR664
分子名称:De novo Beta Sheet Design Protein OR664
著者Tang, Y., Liu, G., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
登録日2016-07-03
公開日2016-09-21
最終更新日2017-11-01
実験手法SOLUTION NMR
主引用文献Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
5KPH
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SOLUTION NMR STRUCTURE OF DENOVO BETA SHEET DESIGN PROTEIN, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR485
分子名称:De novo Beta Sheet Design Protein OR485
著者Tang, Y., Liu, G., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
登録日2016-07-04
公開日2016-09-28
最終更新日2017-11-01
実験手法SOLUTION NMR
主引用文献Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
6CZG
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STRUCTURE OF A REDESIGNED BETA BARREL, B11L5F_LGL
分子名称:b11L5F_LGL
著者Doyle, L.A., Stoddard, B.L.
登録日2018-04-09
公開日2018-09-19
最終更新日2019-04-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
6CZH
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STRUCTURE OF A REDESIGNED BETA BARREL, MFAP0, BOUND TO DFHBI
分子名称:mFAP0, (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one
著者Doyle, L.A., Stoddard, B.L.
登録日2018-04-09
公開日2018-09-19
最終更新日2019-04-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
6CZI
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STRUCTURE OF A REDESIGNED BETA BARREL, MFAP1, BOUND TO DFHBI
分子名称:mFAP1, (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one
著者Doyle, L.A., Stoddard, B.L.
登録日2018-04-09
公開日2018-09-19
最終更新日2019-04-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
6CZJ
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STRUCTURE OF A REDESIGNED BETA BARREL, B10
分子名称:b10, SULFATE ION
著者Doyle, L.A., Stoddard, B.L.
登録日2018-04-09
公開日2018-09-19
最終更新日2019-04-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
6DG5
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STRUCTURE OF A DE NOVO DESIGNED INTERLEUKIN-2/INTERLEUKIN-15 MIMETIC COMPLEX WITH IL-2RB AND IL-2RG
分子名称:Neoleukin-2/15, Interleukin-2 receptor subunit beta, Cytokine receptor common subunit gamma, ...
著者Jude, K.M., Silva, D.-A., Yu, S., Baker, D., Garcia, K.C.
登録日2018-05-16
公開日2019-01-16
最終更新日2019-01-23
実験手法X-RAY DIFFRACTION (2.516 Å)
主引用文献De novo design of potent and selective mimics of IL-2 and IL-15.
Nature, 565, 2019
6DG6
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STRUCTURE OF A DE NOVO DESIGNED INTERLEUKIN-2/INTERLEUKIN-15 MIMETIC
分子名称:Neoleukin-2/15
著者Jude, K.M., Silva, D.-A., Yu, S., Baker, D., Garcia, K.C.
登録日2018-05-16
公開日2019-01-16
最終更新日2019-01-23
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献De novo design of potent and selective mimics of IL-2 and IL-15.
Nature, 565, 2019