7SKL

Complex between S. aureus aureolysin and IMPI mutant I57I

Summary for 7SKL

Entry DOI	10.2210/pdb7skl/pdb
Descriptor	Zinc metalloproteinase aureolysin, IMPI alpha, CALCIUM ION, ... (7 entities in total)
Functional Keywords	metallopeptidase, inhibitor complex, point mutant, hydrolase
Biological source	Staphylococcus aureus More
Total number of polymer chains	6
Total formula weight	83365.42
Authors	Mendes, S.R.,Eckhard, U.,Rodriguez-Banqueri, A.,Guevara, T.,Gomis-Ruth, F.X. (deposition date: 2021-10-21, release date: 2022-01-26, Last modification date: 2023-10-18)
Primary citation	Mendes, S.R.,Eckhard, U.,Rodriguez-Banqueri, A.,Guevara, T.,Czermak, P.,Marcos, E.,Vilcinskas, A. An engineered protein-based submicromolar competitive inhibitor of the Staphylococcus aureus virulence factor aureolysin Comput Struct Biotechnol J, 20:534-544, 2022 Cited by DOI: 10.1016/j.csbj.2022.01.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation