Crystal structure of a de novo designed protein with curved beta-sheet

Summary for 5TPJ

Descriptordenovo NTF2 (2 entities in total)
Functional Keywordsde novo ntf2, de novo protein
Biological sourcesynthetic construct
Total number of polymer chains1
Total molecular weight14927.18
Basanta, B.,Oberdorfer, G.,Marcos, E.,Chidyausiku, T.M.,Sankaran, B.,Baker, D. (deposition date: 2016-10-20, release date: 2017-01-25, Last modification date: 2017-09-20)
Primary citation
Marcos, E.,Basanta, B.,Chidyausiku, T.M.,Tang, Y.,Oberdorfer, G.,Liu, G.,Swapna, G.V.,Guan, R.,Silva, D.A.,Dou, J.,Pereira, J.H.,Xiao, R.,Sankaran, B.,Zwart, P.H.,Montelione, G.T.,Baker, D.
Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355:201-206, 2017
PubMed: 28082595 (PDB entries with the same primary citation)
DOI: 10.1126/science.aah7389
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.27280.8%3.0%1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5tpj
no rotation
Molmil generated image of 5tpj
rotated about x axis by 90°
Molmil generated image of 5tpj
rotated about y axis by 90°