5TPH

Crystal structure of a de novo designed protein homodimer with curved beta-sheet

Summary for 5TPH

Related5TPJ
Descriptorde novo NTF2 homodimer, DI(HYDROXYETHYL)ETHER, CHLORIDE ION, ... (4 entities in total)
Functional Keywordsde novo ntf2, de novo protein
Biological sourcesynthetic construct
Total number of polymer chains2
Total molecular weight28970.76
Authors
Basanta, B.,Marcos, E.,Oberdorfer, G.,Chidyausiku, T.M.,Sankaran, B.,Baker, D. (deposition date: 2016-10-20, release date: 2017-01-25, Last modification date: 2017-09-20)
Primary citation
Marcos, E.,Basanta, B.,Chidyausiku, T.M.,Tang, Y.,Oberdorfer, G.,Liu, G.,Swapna, G.V.,Guan, R.,Silva, D.A.,Dou, J.,Pereira, J.H.,Xiao, R.,Sankaran, B.,Zwart, P.H.,Montelione, G.T.,Baker, D.
Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355:201-206, 2017
PubMed: 28082595 (PDB entries with the same primary citation)
DOI: 10.1126/science.aah7389
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.47 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2592001.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution