Author results

6A4X
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OXIDASE CHAP-H2
分子名称:Bleomycin resistance protein, FE (II) ION
著者Zhang, B., Wang, Y.S., Ge, H.M.
登録日2018-06-21
公開日2018-08-29
最終更新日2018-09-19
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis.
J. Am. Chem. Soc., 140, 2018
6A4Z
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OXIDASE CHAP
分子名称:ChaP protein, FE (II) ION
著者Zhang, B., Ge, H.M.
登録日2018-06-21
公開日2018-08-29
最終更新日2018-09-19
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis.
J. Am. Chem. Soc., 140, 2018
6A52
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OXIDASE CHAP-H1
分子名称:dioxidase ChaP-H1, FE (II) ION
著者Zhang, B., Ge, H.M.
登録日2018-06-21
公開日2018-08-29
最終更新日2018-09-19
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis.
J. Am. Chem. Soc., 140, 2018
6A5F
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THE STRUCTURE OF [4+2] AND [6+4] CYCLASE IN THE BIOSYNTHETIC PATHWAY OF NARGENICIN
分子名称:NgnD
著者Zhang, B., Ge, H.M.
登録日2018-06-23
公開日2019-02-06
最終更新日2019-04-17
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of natural products.
Nature, 568, 2019
6A5G
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THE STRUCTURE OF [4+2] AND [6+4] CYCLASE IN THE BIOSYNTHETIC PATHWAY OF STREPTOSEOMYCIN
分子名称:[4+2] and [4+6] cyclase StmD
著者Zhang, B., Ge, H.M.
登録日2018-06-23
公開日2019-02-06
最終更新日2019-04-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of natural products.
Nature, 568, 2019
6A5H
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THE STRUCTURE OF [4+2] AND [6+4] CYCLASE IN THE BIOSYNTHETIC PATHWAY OF UNIDENTIFIED NATURAL PRODUCT
分子名称:101015D
著者Zhang, B., Ge, H.M.
登録日2018-06-23
公開日2019-02-06
最終更新日2019-04-17
実験手法X-RAY DIFFRACTION (1.618 Å)
主引用文献Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of natural products.
Nature, 568, 2019
6CE0
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CRYSTAL STRUCTURE OF A HIV-1 CLADE B TIER-3 ISOLATE H078.14 UFO-BG ENV TRIMER IN COMPLEX WITH BROADLY NEUTRALIZING FABS PGT124 AND 35O22 AT 4.6 ANGSTROM
分子名称:Envelope glycoprotein gp160, 35O22 Heavy chain, 35O22 Light chain, ...
著者Kumar, S., Sarkar, A., Wilson, I.A.
登録日2018-02-09
公開日2018-12-05
実験手法X-RAY DIFFRACTION (4.602 Å)
主引用文献HIV-1 vaccine design through minimizing envelope metastability.
Sci Adv, 4, 2018
2E0H
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SOLUTION STRUCTURE OF BMKALPHAIT01, AN ALPHA-INSECT TOXIN FROM THE VENOM OF THE CHINESE SCORPION BUTHUS MARTENSI KARSCH
分子名称:Alpha-neurotoxin TX12
著者Tong, X.T., Chen, X., Wu, H.M.
登録日2006-10-08
公開日2007-10-16
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution Structure of BmKalphaIT01, an alpha-Insect Toxin from the Venom of the Chinese Scorpion Buthus martensii Karsch
Biochemistry, 46, 2007
2FYZ
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STRUCTURAL OF MUMPS VIRUS FUSION PROTEIN CORE
分子名称:Fusion glycoprotein F0
著者Lou, Z., Xu, Y., Liu, Y., Rao, Z.
登録日2006-02-08
公開日2007-04-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural characterization of mumps virus fusion protein core
Biochem.Biophys.Res.Commun., 348, 2006
3HHM
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CRYSTAL STRUCTURE OF P110ALPHA H1047R MUTANT IN COMPLEX WITH NISH2 OF P85ALPHA AND THE DRUG WORTMANNIN
分子名称:Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, niSH2 p85alpha, (1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4,3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE
著者Amzel, L.M., Vogelstein, B., Gabelli, S.B., Mandelker, D.
登録日2009-05-15
公開日2009-09-29
最終更新日2018-09-26
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A frequent kinase domain mutation that changes the interaction between PI3K{alpha} and the membrane.
Proc.Natl.Acad.Sci.USA, 106, 2009
3HIZ
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CRYSTAL STRUCTURE OF P110ALPHA H1047R MUTANT IN COMPLEX WITH NISH2 OF P85ALPHA
分子名称:Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 3-kinase regulatory subunit alpha
著者Amzel, L.M., Vogelstein, B., Gabelli, S.B., Mandelker, D.
登録日2009-05-20
公開日2009-09-29
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A frequent kinase domain mutation that changes the interaction between PI3K{alpha} and the membrane.
Proc.Natl.Acad.Sci.USA, 106, 2009
3IEJ
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PYRAZOLE-BASED CATHEPSIN S INHIBITORS WITH ARYLALKYNES AS P1 BINDING ELEMENTS
分子名称:Cathepsin S, 2-[3-{4-chloro-3-[(4-chlorophenyl)ethynyl]phenyl}-1-(3-morpholin-4-ylpropyl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl]-2-oxoethanol
著者Bembenek, S.
登録日2009-07-22
公開日2009-10-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Pyrazole-based cathepsin S inhibitors with arylalkynes as P1 binding elements.
Bioorg.Med.Chem.Lett., 19, 2009
3LRS
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STRUCTURE OF PG16, AN ANTIBODY WITH BROAD AND POTENT NEUTRALIZATION OF HIV-1
分子名称:PG-16 Heavy Chain Fab, PG-16 Light Chain Fab, N-ACETYL-D-GLUCOSAMINE
著者Pancera, M., Kwong, P.D.
登録日2010-02-11
公開日2010-06-09
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1.
J.Virol., 84, 2010
3PIQ
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CRYSTAL STRUCTURE OF HUMAN 2909 FAB, A QUATERNARY STRUCTURE-SPECIFIC ANTIBODY AGAINST HIV-1
分子名称:Human monoclonal antibody 2909 Fab heavy chain, Human monoclonal antibody 2909 Fab light chain
著者Changela, A., Gorny, M.K., Zolla-Pazner, S., Kwong, P.D.
登録日2010-11-07
公開日2011-01-05
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (3.325 Å)
主引用文献Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1.
J.Virol., 85, 2011
3QW9
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CRYSTAL STRUCTURE OF BETAGLYCAN ZP-C DOMAIN
分子名称:Transforming growth factor beta receptor type 3, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
著者Lin, S.J., Jardetzky, T.S.
登録日2011-02-27
公開日2011-04-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of betaglycan zona pellucida (ZP)-C domain provides insights into ZP-mediated protein polymerization and TGF-{beta} binding.
Proc.Natl.Acad.Sci.USA, 108, 2011
3SE8
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CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY VRC03 IN COMPLEX WITH HIV-1 GP120
分子名称:HIV-1 Clade AE strain 93TH057 gp120, Heavy chain of antibody VRC03, Light chain of antibody VRC03, ...
著者Kwong, P.D., Zhou, T.
登録日2011-06-10
公開日2011-08-10
最終更新日2012-08-15
実験手法X-RAY DIFFRACTION (1.895 Å)
主引用文献Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing.
Science, 333, 2011
3SE9
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CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY VRC-PG04 IN COMPLEX WITH HIV-1 GP120
分子名称:HIV-1 Clade AE strain 93TH057 gp120, Heavy chain of antibody VRC-PG04, Light chain of antibody VRC-PG04, ...
著者Kwong, P.D., Zhou, T.
登録日2011-06-10
公開日2011-08-10
最終更新日2011-10-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing.
Science, 333, 2011
4C50
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CRYSTAL STRUCTURE OF THE CATALASE-PEROXIDASE (KATG) D137S MUTANT FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:CATALASE-PEROXIDASE, ALPHA-D-GLUCOSE, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Hersleth, H.-P., Zhao, X., Magliozzo, R.S., Andersson, K.K.
登録日2013-09-10
公開日2013-11-13
最終更新日2013-11-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Access Channel Residues Ser315 and Asp137 in Mycobacterium Tuberculosis Catalase-Peroxidase (Katg) Control Peroxidatic Activation of the Pro-Drug Isoniazid.
Chem.Commun.(Camb.), 49, 2013
4C51
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CRYSTAL STRUCTURE OF THE CATALASE-PEROXIDASE (KATG) R418L MUTANT FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:CATALASE-PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, ALPHA-D-GLUCOSE
著者Hersleth, H.-P., Zhao, X., Magliozzo, R.S., Andersson, K.K.
登録日2013-09-10
公開日2013-11-13
最終更新日2013-11-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Access Channel Residues Ser315 and Asp137 in Mycobacterium Tuberculosis Catalase-Peroxidase (Katg) Control Peroxidatic Activation of the Pro-Drug Isoniazid.
Chem.Commun.(Camb.), 49, 2013
4I3R
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CRYSTAL STRUCTURE OF THE OUTER DOMAIN OF HIV-1 GP120 IN COMPLEX WITH VRC-PG04 SPACE GROUP P3221
分子名称:Outer domain of HIV-1 gp120 (KER2018 OD4.2.2), Heavy chain of VRC-PG04 Fab, Light chain of VRC-PG04 Fab, ...
著者Joyce, M.G., Biertumpfel, C., Nabel, G.J., Kwong, P.D.
登録日2012-11-26
公開日2013-01-09
最終更新日2013-02-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04.
J.Virol., 87, 2013
4I3S
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CRYSTAL STRUCTURE OF THE OUTER DOMAIN OF HIV-1 GP120 IN COMPLEX WITH VRC-PG04 SPACE GROUP P21
分子名称:Outer domain of HIV-1 gp120 (KER2018 OD4.2.2), Heavy chain of VRC-PG04 Fab, Light chain of VRC-PG04 Fab, ...
著者Joyce, M.G., Biertumpfel, C., Nabel, G.J., Kwong, P.D.
登録日2012-11-26
公開日2013-01-09
最終更新日2013-02-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04.
J.Virol., 87, 2013
4JAM
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CRYSTAL STRUCTURE OF BROADLY NEUTRALIZING ANTI-HIV-1 ANTIBODY CH103
分子名称:ANTIGEN BINDING FRAGMENT OF HEAVY CHAIN of CH103, ANTIGEN BINDING FRAGMENT OF LIGHT CHAIN of CH103, SULFATE ION, ...
著者Zhou, T., Moquin, S., Zheng, A., Srivatsan, S., Kwong, P.D.
登録日2013-02-18
公開日2013-04-03
最終更新日2013-05-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus.
Nature, 496, 2013
4JAN
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CRYSTAL STRUCTURE OF BROADLY NEUTRALIZING ANTIBODY CH103 IN COMPLEX WITH HIV-1 GP120
分子名称:ENVELOPE GLYCOPROTEIN GP120 of HIV-1 clade C, ANTIGEN BINDING FRAGMENT OF HEAVY CHAIN of CH103, ANTIGEN BINDING FRAGMENT OF LIGHT CHAIN of CH103, ...
著者Zhou, T., Moquin, S., Zheng, A., Srivatsan, S., Kwong, P.D.
登録日2013-02-18
公開日2013-04-03
最終更新日2019-01-09
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus.
Nature, 496, 2013
4V67
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CRYSTAL STRUCTURE OF A TRANSLATION TERMINATION COMPLEX FORMED WITH RELEASE FACTOR RF2.
分子名称:16S RRNA, P AND E-SITE TRNA(FMET), MRNA, ...
著者Korostelev, A., Asahara, H., Lancaster, L., Laurberg, M., Hirschi, A., Noller, H.F.
登録日2008-10-27
公開日2014-07-09
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of a translation termination complex formed with release factor RF2.
Proc.Natl.Acad.Sci.USA, 105, 2008
4ZNE
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IGG1 FC-FCGAMMARI ECD COMPLEX
分子名称:High affinity immunoglobulin gamma Fc receptor I, Ig gamma-1 chain C region, N-ACETYL-D-GLUCOSAMINE, ...
著者Oganesyan, V.Y., Dall'Acqua, W.F.
登録日2015-05-04
公開日2015-11-11
最終更新日2015-11-18
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structural insights into the interaction of human IgG1 with Fc gamma RI: no direct role of glycans in binding.
Acta Crystallogr.,Sect.D, 71, 2015