3FCS

Structure of complete ectodomain of integrin aIIBb3

Summary for 3FCS

Entry DOI	10.2210/pdb3fcs/pdb
Related	3FCU
Descriptor	Integrin, alpha 2b, MAGNESIUM ION, Integrin beta-3, ... (11 entities in total)
Functional Keywords	beta propeller, rossmann fold, egf domain, cell adhesion, disease mutation, glycoprotein, host-virus interaction, integrin, membrane, phosphoprotein, receptor, transmembrane, cell adhesion-immune system complex, cell adhesion-blood clotting complex, cell adhesion/blood clotting
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	368902.43
Authors	Zhu, J.,Luo, B.-H.,Xiao, T.,Zhang, C.,Nishida, N.,Springer, T.A. (deposition date: 2008-11-22, release date: 2009-01-20, Last modification date: 2023-09-06)
Primary citation	Zhu, J.,Luo, B.H.,Xiao, T.,Zhang, C.,Nishida, N.,Springer, T.A. Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces. Mol.Cell, 32:849-861, 2008 Cited by PubMed: 19111664 DOI: 10.1016/j.molcel.2008.11.018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.55 Å)

Structure validation