3FCS
Structure of complete ectodomain of integrin aIIBb3
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Integrin, alpha 2b | polymer | 959 | 104460.7 | 2 | UniProt (Q17R67) Pfam (PF01839) Pfam (PF08441) Pfam (PF20805) Pfam (PF20806) UniProt (by SIFTS) (P08514) In PDB | Homo sapiens (human) | |
2 | B, D | Integrin beta-3 | polymer | 690 | 76316.9 | 2 | UniProt (P05106) Pfam (PF07965) Pfam (PF17205) Pfam (PF00362) Pfam (PF18372) Pfam (PF07974) In PDB | Homo sapiens (human) | Platelet membrane glycoprotein IIIa, GPIIIa |
3 | E, H, J, K, L... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 7 | In PDB GlyTouCan (G42666HT) | |||
4 | F | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G48068RF) | |||
5 | G | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G62182OO) | |||
6 | I | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G75436UI) | |||
7 | C, D, A, B | CALCIUM ION | non-polymer | 40.1 | 14 | Chemie (CA) | |||
8 | C, D, A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
9 | C, A | IMIDAZOLE | non-polymer | 69.1 | 6 | Chemie (IMD) | |||
10 | D, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
11 | water | water | 18.0 | 678 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 958 (UniProt: Q17R67)
B, D: 1 - 690 (UniProt: P05106)
PDB | External Database | Details |
---|---|---|
Cys 959 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Cys 688 | Pro 714 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 361555.3 | |
Branched | Number of molecules | 10 |
Total formula weight | 5216.9 | |
Non-Polymers* | Number of molecules | 27 |
Total formula weight | 2130.3 | |
All* | Total formula weight | 368902.4 |