5O97
Crystal structure of human BRD4(1) bromodomain in complex with JRMBR4106
Summary for 5O97
Entry DOI | 10.2210/pdb5o97/pdb |
Descriptor | Bromodomain-containing protein 4, (5~{Z})-4-azanyl-5-[(3-methoxy-4-oxidanyl-phenyl)methylidene]-1,3-thiazol-2-one, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | brd4 bromodomain 1(brp4(1)), inhibitor, dna binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 15411.72 |
Authors | Zhu, J.,Marchand, J.R.,Caflisch, A. (deposition date: 2017-06-15, release date: 2018-06-27, Last modification date: 2024-01-17) |
Primary citation | Zhu, J.,Marchand, J.R.,Caflisch, A. Crystal structure of human BRD4(1) bromodomain in complex with JRMBR4106 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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