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1O0E
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BU of 1o0e by Molmil
1.9 Angstrom Crystal Structure of a plant cysteine protease Ervatamin C
分子名称: Ervatamin C, THIOSULFATE
著者Thakurta, P.G, Chakrabarti, C, Biswas, S, Dattagupta, J.K.
登録日2003-02-21
公開日2004-03-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis of the Unusual Stability and Substrate Specificity of Ervatamin C, a Plant Cysteine Protease from Ervatamia coronaria
Biochemistry, 43, 2004
1QDQ
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BU of 1qdq by Molmil
X-RAY CRYSTAL STRUCTURE OF BOVINE CATHEPSIN B-CA074 COMPLEX
分子名称: CATHEPSIN B, [PROPYLAMINO-3-HYDROXY-BUTAN-1,4-DIONYL]-ISOLEUCYL-PROLINE
著者Yamamoto, A.
登録日1999-07-10
公開日2000-07-10
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Substrate specificity of bovine cathepsin B and its inhibition by CA074, based on crystal structure refinement of the complex.
J.Biochem.(Tokyo), 127, 2000
1Q6K
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BU of 1q6k by Molmil
Cathepsin K complexed with t-butyl(1S)-1-cyclohexyl-2-oxoethylcarbamate
分子名称: Cathepsin K, SULFATE ION, TERT-BUTYL(1S)-1-CYCLOHEXYL-2-OXOETHYLCARBAMATE
著者Catalano, J.G, Deaton, D.N, Furfine, E.S, Hassell, A.M, McFadyen, R.B, Miller, A.B, Miller, L.R, Shewchuk, L.M, Willard, D.H, Wright, L.L.
登録日2003-08-13
公開日2004-03-16
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Exploration of the P1 SAR of aldehyde cathepsin K inhibitors
Bioorg.Med.Chem.Lett., 14, 2004
1PIP
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BU of 1pip by Molmil
CRYSTAL STRUCTURE OF PAPAIN-SUCCINYL-GLN-VAL-VAL-ALA-ALA-P-NITROANILIDE COMPLEX AT 1.7 ANGSTROMS RESOLUTION: NONCOVALENT BINDING MODE OF A COMMON SEQUENCE OF ENDOGENOUS THIOL PROTEASE INHIBITORS
分子名称: Papain, SUCCINYL-GLN-VAL-VAL-ALA-ALA-P-NITROANILIDE
著者Yamamoto, A, Tomoo, K, Doi, M, Ohishi, H, Inoue, M, Ishida, T, Yamamoto, D, Tsuboi, S, Okamoto, H, Okada, Y.
登録日1992-10-03
公開日1993-10-31
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of papain-succinyl-Gln-Val-Val-Ala-Ala-p-nitroanilide complex at 1.7-A resolution: noncovalent binding mode of a common sequence of endogenous thiol protease inhibitors.
Biochemistry, 31, 1992
1PPD
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BU of 1ppd by Molmil
RESTRAINED LEAST-SQUARES REFINEMENT OF THE SULFHYDRYL PROTEASE PAPAIN TO 2.0 ANGSTROMS
分子名称: 2-HYDROXYETHYL-THIOPAPAIN, BETA-MERCAPTOETHANOL
著者Jansonius, J.N.
登録日1984-11-06
公開日1985-01-02
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Restrained Least-Squares Refinement of the Sulfhydryl Protease Papain to 2.0 Angstroms
Acta Crystallogr.,Sect.A, 40, 1984
1POP
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BU of 1pop by Molmil
X-RAY CRYSTALLOGRAPHIC STRUCTURE OF A PAPAIN-LEUPEPTIN COMPLEX
分子名称: LEUPEPTIN, METHANOL, PAPAIN
著者Schroder, E, Crawford, C.
登録日1993-06-24
公開日1993-10-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-ray crystallographic structure of a papain-leupeptin complex.
FEBS Lett., 315, 1993
2DC6
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BU of 2dc6 by Molmil
X-ray crystal structure analysis of bovine spleen cathepsin B-CA073 complex
分子名称: BENZYL N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE, GLYCEROL, PHOSPHATE ION, ...
著者Watanabe, D.
登録日2005-12-28
公開日2006-01-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes
To be Published
2DC7
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BU of 2dc7 by Molmil
X-ray crystal structure analysis of bovine spleen cathepsin B-CA042 complex
分子名称: CATHEPSIN B, GLYCEROL, N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-THREONYL-L-ISOLEUCINE, ...
著者Watanabe, D.
登録日2005-12-31
公開日2006-01-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes
To be Published
2DCC
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BU of 2dcc by Molmil
X-ray crystal structure analysis of bovine spleen cathepsin B-CA077 complex
分子名称: BENZYL N-({(2S,3S)-3-[(BENZYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE, CATHEPSIN B, GLYCEROL, ...
著者Watanabe, D.
登録日2006-01-01
公開日2006-01-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes
To be Published
2DCD
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BU of 2dcd by Molmil
X-ray crystal structure analysis of bovine spleen cathepsin B-CA078 complex
分子名称: CATHEPSIN B, GLYCEROL, N-({(2S,3S)-3-[(BENZYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINE, ...
著者Watanabe, D.
登録日2006-01-01
公開日2006-01-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes
To be Published
2DCB
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BU of 2dcb by Molmil
X-ray crystal structure analysis of bovine spleen cathepsin B-CA076 complex
分子名称: CATHEPSIN B, GLYCEROL, N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ISOLEUCINE, ...
著者Watanabe, D.
登録日2006-01-01
公開日2006-01-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes
To be Published
2DCA
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BU of 2dca by Molmil
X-ray crystal structure analysis of bovine spleen cathepsin B-CA075 complex
分子名称: CATHEPSIN B, GLYCEROL, N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ALANINE, ...
著者Watanabe, D.
登録日2006-01-01
公開日2006-01-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes
To be Published
2DC9
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BU of 2dc9 by Molmil
X-ray crystal structure analysis of bovine spleen cathepsin B-CA074Me complex
分子名称: CATHEPSIN B, GLYCEROL, METHYL N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE, ...
著者Watanabe, D.
登録日2005-12-31
公開日2006-01-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes
To be Published
2DC8
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BU of 2dc8 by Molmil
X-ray crystal structure analysis of bovine spleen cathepsin B-CA059 complex
分子名称: CATHEPSIN B, GLYCEROL, N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCINE, ...
著者Watanabe, D.
登録日2005-12-31
公開日2006-01-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes
To be Published
2AIM
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BU of 2aim by Molmil
CRUZAIN INHIBITED WITH BENZOYL-ARGININE-ALANINE-FLUOROMETHYLKETONE
分子名称: BENZOYL-ARGININE-ALANINE-FLUORO-METHYL KETONE, CRUZAIN
著者Gillmor, S.A, Fletterick, R.J.
登録日1997-04-21
公開日1997-10-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural determinants of specificity in the cysteine protease cruzain.
Protein Sci., 6, 1997
2BDL
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BU of 2bdl by Molmil
Cathepsin K complexed with a pyrrolidine ketoamide-based inhibitor
分子名称: (3S)-1-{[(3,5-DIMETHYLISOXAZOL-4-YL)AMINO]CARBONYL}-4,4-DIMETHYLPYRROLIDIN-3-YL{(1S)-1-[1-HYDROXY-2-OXO-2-{[(1R)-1-PHENYLETHYL]AMINO}ETHYL]PENTYL}CARBAMATE, Cathepsin K
著者Shewchuk, L.M.
登録日2005-10-20
公開日2006-03-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Novel, potent P2-P3 pyrrolidine derivatives of ketoamide-based cathepsin K inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
2BDZ
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BU of 2bdz by Molmil
Mexicain from Jacaratia mexicana
分子名称: Mexicain, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE
著者Gavira, J.A, Oliver-Salvador, M.C, Gonzalez-Ramirez, L.A, Soriano-Garcia, M, Garcia-Ruiz, J.M.
登録日2005-10-21
公開日2006-10-03
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallographic structure of Mexicain from Jacaratia mexicana
To be Published
2AS8
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BU of 2as8 by Molmil
Crystal structure of mature and fully active Der p 1 allergen
分子名称: MAGNESIUM ION, Major mite fecal allergen Der p 1
著者de Halleux, S, Stura, E, VanderElst, L, Carlier, V, Jacquemin, M, Saint-Remy, J.-M.
登録日2005-08-23
公開日2005-12-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Three-dimensional structure and IgE-binding properties of mature fully active Der p 1, a clinically relevant major allergen
J.Allergy Clin.Immunol., 117, 2006
2AUX
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BU of 2aux by Molmil
Cathepsin K complexed with a semicarbazone inhibitor
分子名称: (1R)-2-METHYL-1-(PHENYLMETHYL)PROPYL[(1S)-1-FORMYLPENTYL]CARBAMATE, Cathepsin K
著者Adkison, K.K, Barrett, D.G, Deaton, D.N, Gampe, R.T, Hassell, A.M, Long, S.T, McFadyen, R.B, Miller, A.B, Miller, L.R, Shewchuk, L.M.
登録日2005-08-29
公開日2006-08-08
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Semicarbazone-based inhibitors of cathepsin K, are they prodrugs for aldehyde inhibitors?
Bioorg.Med.Chem.Lett., 16, 2006
2B1M
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BU of 2b1m by Molmil
Crystal structure of a papain-fold protein without the catalytic cysteine from seeds of Pachyrhizus erosus
分子名称: DI(HYDROXYETHYL)ETHER, SPE31, TETRAETHYLENE GLYCOL, ...
著者Zhang, M, Wei, Z, Chang, S.
登録日2005-09-16
公開日2006-10-03
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a papain-fold protein without the catalytic residue: a novel member in the cysteine proteinase family
J.Mol.Biol., 358, 2006
2AUZ
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BU of 2auz by Molmil
Cathepsin K complexed with a semicarbazone inhibitor
分子名称: 1-(PHENYLMETHYL)CYCLOPENTYL[(1S)-1-FORMYLPENTYL]CARBAMATE, Cathepsin K, SULFATE ION
著者Adkison, K.K, Barrett, D.G, Deaton, D.N, Gampe, R.T, Hassell, A.M, Long, S.T, McFadyen, R.B, Miller, A.B, Miller, L.R, Shewchuk, L.M.
登録日2005-08-29
公開日2006-08-08
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Semicarbazone-based inhibitors of cathepsin K, are they prodrugs for aldehyde inhibitors?
Bioorg.Med.Chem.Lett., 16, 2006
2F7D
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BU of 2f7d by Molmil
A mutant rabbit cathepsin K with a nitrile inhibitor
分子名称: (1R,2R)-N-(2-AMINOETHYL)-2-{[(4-METHOXYPHENYL)SULFONYL]METHYL}CYCLOHEXANECARBOXAMIDE, Cathepsin K
著者Somoza, J.R.
登録日2005-11-30
公開日2006-03-07
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Beta-substituted cyclohexanecarboxamide: a nonpeptidic framework for the design of potent inhibitors of cathepsin K.
J.Med.Chem., 49, 2006
2F1G
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BU of 2f1g by Molmil
Cathepsin S in complex with non-covalent 2-(Benzoxazol-2-ylamino)-acetamide
分子名称: Cathepsin S, GLYCEROL, N~2~-1,3-BENZOXAZOL-2-YL-3-CYCLOHEXYL-N-{2-[(4-METHOXYPHENYL)AMINO]ETHYL}-L-ALANINAMIDE
著者Spraggon, G, Hornsby, M, Lesley, S.A, Tully, D.C, Harris, J.L, Karenewsky, D.S, Kulathila, R, Clark, K.
登録日2005-11-14
公開日2006-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Synthesis and evaluation of arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Part 3: Heterocyclic P3.
Bioorg.Med.Chem.Lett., 16, 2006
5QC3
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BU of 5qc3 by Molmil
Crystal structure of human Cathepsin-S with bound ligand
分子名称: 1-{3-[3-{[2-(4-fluoropiperidin-1-yl)ethyl]sulfanyl}-4-(trifluoromethyl)phenyl]-1-[(2S)-2-hydroxy-3-(piperidin-1-yl)propyl]-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl}-2-hydroxyethan-1-one, Cathepsin S
著者Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K.
登録日2017-08-04
公開日2017-12-20
最終更新日2021-11-17
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Crystal structure of human Cathepsin-S with bound ligand
To be published
5QCJ
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Crystal structure of human Cathepsin-S with bound ligand
分子名称: 5-hydroxy-3-{1-[(2S)-2-hydroxy-3-{5-(methylsulfonyl)-3-[4-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-1-yl}propyl]piperidin-4-yl}-1H-pyrrolo[3,2-c]pyridin-5-ium, Cathepsin S, SULFATE ION
著者Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K.
登録日2017-08-04
公開日2017-12-20
最終更新日2021-11-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of human Cathepsin-S with bound ligand
To be published

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