2DC7

X-ray crystal structure analysis of bovine spleen cathepsin B-CA042 complex

Summary for 2DC7

• Entry DOI: 10.2210/pdb2dc7/pdb
• Related: 1ITO 1QDQ 2DC6 2DC8 2DC9 2DCA 2DCB 2DCC 2DCD
• Descriptor: CATHEPSIN B, PHOSPHATE ION, N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-THREONYL-L-ISOLEUCINE, ... (5 entities in total)
• Functional Keywords: cathepsin b, cysteine protease, ca042, hydrolase, ec 3.4.22.1
• Biological source: Bos taurus (cattle)
• Total number of polymer chains: 1
• Total formula weight: 28480.49

Authors

Watanabe, D. (deposition date: 2005-12-31, release date: 2006-01-24, Last modification date: 2023-10-25)

• Primary citation: Watanabe, D.,Yamamoto, A.,Matsumoto, K.,Murata, M.,Kitamura, K.,Tomoo, K.,Ishida, T.; Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes; To be Published,

Experimental method

X-RAY DIFFRACTION (1.94 Å)