2DC8
X-ray crystal structure analysis of bovine spleen cathepsin B-CA059 complex
Summary for 2DC8
Entry DOI | 10.2210/pdb2dc8/pdb |
Related | 1ITO 1QDQ 2DC6 2DC7 2DC9 2DCA 2DCB 2DCC 2DCD |
Descriptor | CATHEPSIN B, PHOSPHATE ION, N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCINE, ... (5 entities in total) |
Functional Keywords | cathepsin b, cysteine protease, ca059, hydrolase, ec 3.4.22.1 |
Biological source | Bos taurus (cattle) |
Total number of polymer chains | 1 |
Total formula weight | 28379.38 |
Authors | Watanabe, D. (deposition date: 2005-12-31, release date: 2006-01-24, Last modification date: 2023-10-25) |
Primary citation | Watanabe, D.,Yamamoto, A.,Matsumoto, K.,Murata, M.,Kitamura, K.,Tomoo, K.,Ishida, T. Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes To be Published, |
Experimental method | X-RAY DIFFRACTION (1.94 Å) |
Structure validation
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