1ITO

Crystal Structure Analysis of Bovine Spleen Cathepsin B-E64c complex

Summary for 1ITO

• Entry DOI: 10.2210/pdb1ito/pdb
• Related: 1DQD
• Descriptor: Cathepsin B, N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-2-METHYL-BUTANE (3 entities in total)
• Functional Keywords: cathepsin b, cysteine protease, e64c, hydrolase
• Biological source: Bos taurus (cattle)
• Cellular location: Lysosome : P07688
• Total number of polymer chains: 1
• Total formula weight: 28235.43

Authors

Yamamoto, A.,Tomoo, T.,Matsugi, K.,Hara, T.,In, Y.,Murata, M.,Kitamura, K.,Ishida, T. (deposition date: 2002-01-19, release date: 2003-01-19, Last modification date: 2023-10-25)

• Primary citation: Yamamoto, A.,Tomoo, T.,Matsugi, K.,Hara, T.,In, Y.,Murata, M.,Kitamura, K.,Ishida, T.; Structural basis for development of cathepsin B-specific noncovalent-type inhibitor: crystal structure of cathepsin B-E64c complex; BIOCHIM.BIOPHYS.ACTA, 1597:244-251, 2002; PubMed: 12044902; DOI: 10.1016/S0167-4838(02)00284-4

Experimental method

X-RAY DIFFRACTION (2.286 Å)