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2DCC

X-ray crystal structure analysis of bovine spleen cathepsin B-CA077 complex

Summary for 2DCC
Entry DOI10.2210/pdb2dcc/pdb
Related1ITO 1QDQ 2DC6 2DC7 2DC8 2DC9 2DCA 2DCB 2DCD
DescriptorCATHEPSIN B, PHOSPHATE ION, BENZYL N-({(2S,3S)-3-[(BENZYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE, ... (5 entities in total)
Functional Keywordscathepsin b, cysteine protease, ca077, hydrolase, ec 3.4.22.1
Biological sourceBos taurus (cattle)
Total number of polymer chains1
Total formula weight28627.71
Authors
Watanabe, D. (deposition date: 2006-01-01, release date: 2006-01-24, Last modification date: 2023-10-25)
Primary citationWatanabe, D.,Yamamoto, A.,Matsumoto, K.,Murata, M.,Kitamura, K.,Tomoo, K.,Ishida, T.
Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes
To be Published,
Experimental method
X-RAY DIFFRACTION (1.93 Å)
Structure validation

217705

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