5VSK
| Structure of DUB complex | 分子名称: | 7-chloro-3-({4-hydroxy-1-[(3S)-3-phenylbutanoyl]piperidin-4-yl}methyl)quinazolin-4(3H)-one, Ubiquitin carboxyl-terminal hydrolase 7, ZINC ION | 著者 | Seo, H.-Y, Dhe-Paganon, S. | 登録日 | 2017-05-11 | 公開日 | 2017-12-20 | 最終更新日 | 2018-01-03 | 実験手法 | X-RAY DIFFRACTION (3.33 Å) | 主引用文献 | Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7. Cell Chem Biol, 24, 2017
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1W6V
| Solution structure of the DUSP domain of hUSP15 | 分子名称: | UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15 | 著者 | De Jong, R.D, Ab, E, Diercks, T, Truffault, V, Daniels, M, Kaptein, R, Folkers, G.E. | 登録日 | 2004-08-24 | 公開日 | 2006-01-12 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the Human Ubiquitin-Specific Protease 15 Dusp Domain. J.Biol.Chem., 281, 2006
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5NGE
| Crystal structure of USP7 in complex with the non-covalent inhibitor, FT671 | 分子名称: | 5-[[1-[(3~{S})-4,4-bis(fluoranyl)-3-(3-fluoranylpyrazol-1-yl)butanoyl]-4-oxidanyl-piperidin-4-yl]methyl]-1-(4-fluorophenyl)pyrazolo[3,4-d]pyrimidin-4-one, Ubiquitin carboxyl-terminal hydrolase 7 | 著者 | Turnbull, A.P, Krajewski, W.W, Ioannidis, S, Kessler, B.M, Komander, D. | 登録日 | 2017-03-17 | 公開日 | 2017-10-18 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Molecular basis of USP7 inhibition by selective small-molecule inhibitors. Nature, 550, 2017
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5NGF
| Crystal structure of USP7 in complex with the covalent inhibitor, FT827 | 分子名称: | 1,2-ETHANEDIOL, Ubiquitin carboxyl-terminal hydrolase 7, ~{N}-[2-[4-[4-[(1-methyl-4-oxidanylidene-pyrazolo[3,4-d]pyrimidin-5-yl)methyl]-4-oxidanyl-piperidin-1-yl]carbonylphenyl]phenyl]ethanesulfonamide | 著者 | Krajewski, W.W, Turnbull, A.P, Ioannidis, S, Kessler, B.M, Komander, D. | 登録日 | 2017-03-17 | 公開日 | 2017-10-18 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Molecular basis of USP7 inhibition by selective small-molecule inhibitors. Nature, 550, 2017
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5CHV
| Crystal structure of USP18-ISG15 complex | 分子名称: | CHLORIDE ION, SULFATE ION, Ubiquitin-like protein ISG15, ... | 著者 | Fritz, G, Basters, A. | 登録日 | 2015-07-10 | 公開日 | 2016-09-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.005 Å) | 主引用文献 | Structural basis of the specificity of USP18 toward ISG15. Nat. Struct. Mol. Biol., 24, 2017
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5CHT
| Crystal structure of USP18 | 分子名称: | Ubl carboxyl-terminal hydrolase 18, ZINC ION | 著者 | Fritz, G, Basters, A. | 登録日 | 2015-07-10 | 公開日 | 2016-06-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis of the specificity of USP18 toward ISG15. Nat. Struct. Mol. Biol., 24, 2017
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5K1A
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5K1C
| Crystal structure of the UAF1/WDR20/USP12 complex | 分子名称: | PHOSPHATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE, Ubiquitin carboxyl-terminal hydrolase 12, ... | 著者 | Li, H, D'Andrea, A.D, Zheng, N. | 登録日 | 2016-05-18 | 公開日 | 2016-07-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20. Mol.Cell, 63, 2016
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5K16
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5K1B
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6GHA
| USP15 catalytic domain structure | 分子名称: | Ubiquitin carboxyl-terminal hydrolase 15,Ubiquitin carboxyl-terminal hydrolase 15, ZINC ION | 著者 | Ward, S.J, Gratton, H.E, Caulton, S.G, Emsley, J, Dreveny, I. | 登録日 | 2018-05-06 | 公開日 | 2018-09-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | The structure of the deubiquitinase USP15 reveals a misaligned catalytic triad and an open ubiquitin-binding channel. J. Biol. Chem., 293, 2018
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6GH9
| USP15 catalytic domain in complex with small molecule | 分子名称: | 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, DIMETHYL SULFOXIDE, Ubiquitin carboxyl-terminal hydrolase 15, ... | 著者 | Ward, S.J, Gratton, H.E, Caulton, S.G, Emsley, J, Dreveny, I. | 登録日 | 2018-05-06 | 公開日 | 2018-09-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | The structure of the deubiquitinase USP15 reveals a misaligned catalytic triad and an open ubiquitin-binding channel. J. Biol. Chem., 293, 2018
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5GVI
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5CVL
| WDR48 (UAF-1), residues 2-580 | 分子名称: | GOLD ION, PHOSPHATE ION, WD repeat-containing protein 48 | 著者 | HARRIS, S.F, YIN, J. | 登録日 | 2015-07-27 | 公開日 | 2015-10-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46. Structure, 23, 2015
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8OYP
| Crystal structure of Ubiquitin specific protease 11 (USP11) in complex with a substrate mimetic | 分子名称: | CADMIUM ION, CHLORIDE ION, GLYCEROL, ... | 著者 | Maurer, S.K, Caulton, S.G, Ward, S.J, Emsley, J, Dreveny, I. | 登録日 | 2023-05-05 | 公開日 | 2023-10-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Ubiquitin-specific protease 11 structure in complex with an engineered substrate mimetic reveals a molecular feature for deubiquitination selectivity. J.Biol.Chem., 299, 2023
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6KAC
| Cryo-EM structure of the C2S2-type PSII-LHCII supercomplex from Chlamydomonas reihardtii | 分子名称: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | 著者 | Sheng, X, Li, A.J, Song, D.F, Liu, Z.F. | 登録日 | 2019-06-21 | 公開日 | 2019-10-23 | 最終更新日 | 2019-12-25 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural insight into light harvesting for photosystem II in green algae. Nat.Plants, 5, 2019
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4MSX
| Crystal structure of an essential yeast splicing factor | 分子名称: | ACETATE ION, Pre-mRNA-splicing factor SAD1, ZINC ION | 著者 | Hadjivassiliou, H, Guthrie, C, Rosenberg, O.S. | 登録日 | 2013-09-18 | 公開日 | 2014-04-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | The crystal structure of S. cerevisiae Sad1, a catalytically inactive deubiquitinase that is broadly required for pre-mRNA splicing. Rna, 20, 2014
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5QYE
| PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry E12a | 分子名称: | (2R)-6-amino-3-methyl-2,3-dihydro-1,3-benzoxazol-2-ol, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ... | 著者 | Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. | 登録日 | 2020-02-12 | 公開日 | 2020-06-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
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8SY2
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8SY3
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1R0N
| Crystal Structure of Heterodimeric Ecdsyone receptor DNA binding complex | 分子名称: | Ecdsyone Response Element, Ecdysone Response Element, Ecdysone receptor, ... | 著者 | Devarakonda, S, Harp, J.M, Kim, Y, Ozyhar, A, Rastinejad, F. | 登録日 | 2003-09-22 | 公開日 | 2003-10-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of the heterodimeric Ecdysone Receptor DNA-binding complex Embo J., 22, 2003
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4WA6
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8XPN
| The Crystal Structure of USP8 from Biortus. | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ubiquitin carboxyl-terminal hydrolase 8, ... | 著者 | Wang, F, Cheng, W, Yuan, Z, Lin, D, Wang, J. | 登録日 | 2024-01-04 | 公開日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The Crystal Structure of USP8 from Biortus. To Be Published
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4W4U
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1NB8
| Structure of the catalytic domain of USP7 (HAUSP) | 分子名称: | Ubiquitin carboxyl-terminal hydrolase 7 | 著者 | Hu, M, Li, P, Li, M, Li, W, Yao, T, Wu, J.-W, Gu, W, Cohen, R.E, Shi, Y. | 登録日 | 2002-12-02 | 公開日 | 2003-01-07 | 最終更新日 | 2018-04-04 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde Cell(Cambridge,Mass.), 111, 2002
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