3EVB
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3EVD
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3EVG
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3FX7
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6BVK
| Ras:SOS:Ras in complex with a small molecule activator | 分子名称: | FORMIC ACID, GLYCEROL, GTPase HRas, ... | 著者 | Phan, J, Abbott, J, Fesik, S.W. | 登録日 | 2017-12-13 | 公開日 | 2018-10-24 | 最終更新日 | 2019-05-01 | 実験手法 | X-RAY DIFFRACTION (1.799 Å) | 主引用文献 | Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling. J. Med. Chem., 61, 2018
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8HNO
| Archaeal transcription factor Wild type | 分子名称: | Archaeal transcription regulator | 著者 | Bae, D.W, Cha, S.S. | 登録日 | 2022-12-08 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | An archaeal transcription factor EnfR with a novel 'eighth note' fold controls hydrogen production of a hyperthermophilic archaeon Thermococcus onnurineus NA1. Nucleic Acids Res., 51, 2023
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8HNP
| Archaeal transcription factor Mutant | 分子名称: | Archaeal transcription regulator | 著者 | Bae, D.W, Cha, S.S. | 登録日 | 2022-12-08 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.39 Å) | 主引用文献 | An archaeal transcription factor EnfR with a novel 'eighth note' fold controls hydrogen production of a hyperthermophilic archaeon Thermococcus onnurineus NA1. Nucleic Acids Res., 51, 2023
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5E1T
| Crystal structure of TRAF1 TRAF domain | 分子名称: | TNF receptor-associated factor 1 | 著者 | Park, H.H, Kim, C.M. | 登録日 | 2015-09-30 | 公開日 | 2016-12-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of TRAF1 TRAF domain and its implications in the TRAF1-mediated intracellular signaling pathway Sci Rep, 6, 2016
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5EY0
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5EY1
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5GGU
| Crystal structure of tremelimumab Fab | 分子名称: | heavy chain, light chain | 著者 | Heo, Y.S. | 登録日 | 2016-06-16 | 公開日 | 2016-11-09 | 最終更新日 | 2016-11-16 | 実験手法 | X-RAY DIFFRACTION (2.292 Å) | 主引用文献 | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGS
| PD-1 in complex with pembrolizumab Fab | 分子名称: | Programmed cell death protein 1, heavy chain, light chain | 著者 | Heo, Y.S. | 登録日 | 2016-06-16 | 公開日 | 2016-11-09 | 最終更新日 | 2016-11-16 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGV
| CTLA-4 in complex with tremelimumab Fab | 分子名称: | Cytotoxic T-lymphocyte protein 4, heavy chain, light chain | 著者 | Heo, Y.S. | 登録日 | 2016-06-16 | 公開日 | 2016-11-09 | 最終更新日 | 2016-11-16 | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | 主引用文献 | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGT
| PD-L1 in complex with BMS-936559 Fab | 分子名称: | IGK@ protein, IgG H chain, Programmed cell death 1 ligand 1 | 著者 | Heo, Y.S. | 登録日 | 2016-06-16 | 公開日 | 2016-11-09 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GLG
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5GJN
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5GGR
| PD-1 in complex with nivolumab Fab | 分子名称: | Programmed cell death protein 1, heavy chain, light chain | 著者 | Heo, Y.S. | 登録日 | 2016-06-16 | 公開日 | 2016-11-09 | 最終更新日 | 2016-11-16 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GJM
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5GGQ
| Crystal structure of Nivolumab Fab fragment | 分子名称: | nivolumab heavy chain, nivolumab light chain | 著者 | Heo, Y.S. | 登録日 | 2016-06-16 | 公開日 | 2016-11-09 | 最終更新日 | 2016-11-16 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GJP
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5G1D
| The complex structure of syntenin-1 PDZ domain with c-terminal extension | 分子名称: | SYNDECAN-4, SYNTENIN-1 | 著者 | Lee, I, Kim, H, Yun, J.H, Lee, W. | 登録日 | 2016-03-25 | 公開日 | 2016-11-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | New Structural Insight of C-Terminal Region of Syntenin-1, Enhancing the Molecular Dimerization and Inhibitory Function Related on Syndecan-4 Signaling. Sci.Rep., 6, 2016
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5G1E
| The complex structure of syntenin-1 PDZ domain with c-terminal extension | 分子名称: | SYNTENIN-1 | 著者 | Lee, I, Kim, H, Yun, J.H, Lee, W. | 登録日 | 2016-03-25 | 公開日 | 2016-11-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | New Structural Insight of C-Terminal Region of Syntenin-1, Enhancing the Molecular Dimerization and Inhibitory Function Related on Syndecan-4 Signaling. Sci.Rep., 6, 2016
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7CM4
| Crystal Structure of COVID-19 virus spike receptor-binding domain complexed with a neutralizing antibody CT-P59 | 分子名称: | 1,2-ETHANEDIOL, IgG heavy chain, IgG light chain, ... | 著者 | Kim, Y.G, Jeong, J.H, Bae, J.S, Lee, J. | 登録日 | 2020-07-24 | 公開日 | 2021-01-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike protein. Nat Commun, 12, 2021
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7CAZ
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7CAW
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