5GGU

Crystal structure of tremelimumab Fab

Summary for 5GGU

Entry DOI	10.2210/pdb5ggu/pdb
Related	5GGQ 5GGR 5GGS 5GGT 5GGV
Descriptor	heavy chain, light chain (3 entities in total)
Functional Keywords	antibody, immune system
Biological source	Homo sapiens More
Total number of polymer chains	4
Total formula weight	98715.86
Authors	Heo, Y.S. (deposition date: 2016-06-16, release date: 2016-11-09, Last modification date: 2016-11-16)
Primary citation	Lee, J.Y.,Lee, H.T.,Shin, W.,Chae, J.,Choi, J.,Kim, S.H.,Lim, H.,Won Heo, T.,Park, K.Y.,Lee, Y.J.,Ryu, S.E.,Son, J.Y.,Lee, J.U.,Heo, Y.S. Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7:13354-13354, 2016 Cited by PubMed: 27796306 DOI: 10.1038/ncomms13354 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.292 Å)

Structure validation