5GGT

PD-L1 in complex with BMS-936559 Fab

Summary for 5GGT

• Entry DOI: 10.2210/pdb5ggt/pdb
• Related: 5GGQ 5GGR 5GGS 5GGU 5GGV
• Descriptor: Programmed cell death 1 ligand 1, IgG H chain, IGK@ protein (3 entities in total)
• Functional Keywords: antibody, immune system
• Biological source: Homo sapiens (Human); More
• Cellular location: Isoform 1: Cell membrane ; Single-pass type I membrane protein . Isoform 2: Endomembrane system ; Single-pass type I membrane protein : Q9NZQ7
• Total number of polymer chains: 3
• Total formula weight: 61728.31

Authors

Heo, Y.S. (deposition date: 2016-06-16, release date: 2016-11-09, Last modification date: 2024-03-20)

• Primary citation: Lee, J.Y.,Lee, H.T.,Shin, W.,Chae, J.,Choi, J.,Kim, S.H.,Lim, H.,Won Heo, T.,Park, K.Y.,Lee, Y.J.,Ryu, S.E.,Son, J.Y.,Lee, J.U.,Heo, Y.S.; Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy; Nat Commun, 7:13354-13354, 2016; PubMed: 27796306; DOI: 10.1038/ncomms13354

Experimental method

X-RAY DIFFRACTION (2.8 Å)