5GGQ

Crystal structure of Nivolumab Fab fragment

Summary for 5GGQ

Entry DOI	10.2210/pdb5ggq/pdb
Related	5GGR 5GGS 5GGT 5GGU 5GGV
Descriptor	nivolumab light chain, nivolumab heavy chain (3 entities in total)
Functional Keywords	therapeutic antibody, immune system
Biological source	Homo sapiens More
Total number of polymer chains	2
Total formula weight	47671.07
Authors	Heo, Y.S. (deposition date: 2016-06-16, release date: 2016-11-09, Last modification date: 2016-11-16)
Primary citation	Lee, J.Y.,Lee, H.T.,Shin, W.,Chae, J.,Choi, J.,Kim, S.H.,Lim, H.,Won Heo, T.,Park, K.Y.,Lee, Y.J.,Ryu, S.E.,Son, J.Y.,Lee, J.U.,Heo, Y.S. Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7:13354-13354, 2016 Cited by PubMed: 27796306 DOI: 10.1038/ncomms13354 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation