7CM4

Crystal Structure of COVID-19 virus spike receptor-binding domain complexed with a neutralizing antibody CT-P59

Summary for 7CM4

• Entry DOI: 10.2210/pdb7cm4/pdb
• Descriptor: Spike glycoprotein, IgG heavy chain, IgG light chain, ... (7 entities in total)
• Functional Keywords: sars-cov-2, spike, receptor binding domain, rbd, igg, fab, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 3
• Total formula weight: 99973.25

Authors

Kim, Y.G.,Jeong, J.H.,Bae, J.S.,Lee, J. (deposition date: 2020-07-24, release date: 2021-01-20, Last modification date: 2023-11-29)

• Primary citation: Kim, C.,Ryu, D.K.,Lee, J.,Kim, Y.I.,Seo, J.M.,Kim, Y.G.,Jeong, J.H.,Kim, M.,Kim, J.I.,Kim, P.,Bae, J.S.,Shim, E.Y.,Lee, M.S.,Kim, M.S.,Noh, H.,Park, G.S.,Park, J.S.,Son, D.,An, Y.,Lee, J.N.,Kwon, K.S.,Lee, J.Y.,Lee, H.,Yang, J.S.,Kim, K.C.,Kim, S.S.,Woo, H.M.,Kim, J.W.,Park, M.S.,Yu, K.M.,Kim, S.M.,Kim, E.H.,Park, S.J.,Jeong, S.T.,Yu, C.H.,Song, Y.,Gu, S.H.,Oh, H.,Koo, B.S.,Hong, J.J.,Ryu, C.M.,Park, W.B.,Oh, M.D.,Choi, Y.K.,Lee, S.Y.; A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike protein.; Nat Commun, 12:288-288, 2021; PubMed: 33436577; DOI: 10.1038/s41467-020-20602-5

Experimental method

X-RAY DIFFRACTION (2.71 Å)