7CM4

Crystal Structure of COVID-19 virus spike receptor-binding domain complexed with a neutralizing antibody CT-P59

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Spike glycoprotein	polymer	226	25634.8	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	S glycoprotein,E2,Peplomer protein
2	H	IgG heavy chain	polymer	458	50547.1	1		Homo sapiens
3	L	IgG light chain	polymer	216	22655.0	1		Homo sapiens
4	B	alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		894.8	1	In PDB GlyTouCan (G17392HI)
5	H, L	NICKEL (II) ION	non-polymer		58.7	2	Chemie (NI)
6	L	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
7		water	water		18.0	65	Chemie (HOH)

Sequence modifications

A: 319 - 536 (UniProt: P0DTC2)

PDB	External Database	Details
His 537	-	expression tag
His 538	-	expression tag
His 539	-	expression tag
His 540	-	expression tag
His 541	-	expression tag
His 542	-	expression tag
His 543	-	expression tag
His 544	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	98836.9
Branched	Number of molecules	1
	Total formula weight	894.8
Non-Polymers*	Number of molecules	4
	Total formula weight	241.5
All*	Total formula weight	99973.3

*Water molecules are not included.