PDB: 8258 resultsInfo pagesStatus searchChemie searchBIRD

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8SN1	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 6) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SN0	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 5) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SMZ	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (Class 4) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SMY	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 3) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SMX	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 2) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SMW	Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 1) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-04-26 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SMJ	Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGGAATGGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1 Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2023-04-26 Release date: 2023-11-29 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.39 Å) Cite: Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors. Structure, 32, 2024
8SMH	Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGGAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2023-04-26 Release date: 2023-11-29 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.37 Å) Cite: Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors. Structure, 32, 2024
8SKS	human liver mitochondrial Superoxide dismutase [Mn] Descriptor: MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial Authors: Zhang, Z, Tringides, M. Deposit date: 2023-04-20 Release date: 2024-02-21 Method: ELECTRON MICROSCOPY (2.91 Å) Cite: High-Resolution Structural Proteomics of Mitochondria Using the 'Build and Retrieve' Methodology. Mol.Cell Proteomics, 22, 2023
8SJD	Cryo-EM structure of the Hermes transposase bound to two right-ends of its DNA transposon. Descriptor: DNA (46-MER), DNA (55-MER), DNA (8-MER), ... Authors: Lannes, L, Dyda, F. Deposit date: 2023-04-17 Release date: 2023-08-02 Method: ELECTRON MICROSCOPY (5.1 Å) Cite: Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding. Nat Commun, 14, 2023
8SH2	KLHDC2 in complex with EloB and EloC Descriptor: Elongin-B, Elongin-C, Kelch domain-containing protein 2 Authors: Digianantonio, K.M, Bekes, M. Deposit date: 2023-04-13 Release date: 2024-01-03 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.74 Å) Cite: Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules. Nat.Struct.Mol.Biol., 31, 2024
8SD0	Cryo-EM structure of RIG-I in complex with p3SLR14 Descriptor: Antiviral innate immune response receptor RIG-I, ZINC ION, p3SLR14 Authors: Wang, W, Pyle, A.M. Deposit date: 2023-04-06 Release date: 2024-03-13 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Cryo-EM structure of RIG-I in complex with p3SLR14 To Be Published
8SCZ	Cryo-EM structure of 14aa-GS RIG-I in complex with p3SLR30 Descriptor: Antiviral innate immune response receptor RIG-I, ZINC ION, p3SLR30 Authors: Wang, W, Pyle, A.M. Deposit date: 2023-04-06 Release date: 2024-03-13 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Cryo-EM structure of 14aa-GS RIG-I in complex with p3SLR30 To Be Published
8SCB	Terminating ribosome with SRI-41315 Descriptor: (2S,4aS)-2-cyclobutyl-10-methyl-3-phenyl-2,10-dihydropyrimido[4,5-b]quinoline-4,5(3H,4aH)-dione, 18S_rRNA, 28S_rRNA, ... Authors: Yip, M.C.J, Coelho, J.P.L, Oltion, K, Tauton, J, Shao, S. Deposit date: 2023-04-05 Release date: 2023-12-27 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Structure and consequences of eRF1 glued to the ribosomal decoding center To Be Published
8S5N	RNA polymerase II core initially transcribing complex with an ordered RNA of 12 nt Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. Deposit date: 2024-02-24 Release date: 2024-04-10 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
8S55	RNA polymerase II early elongation complex bound to TFIIE and TFIIF - state a (composite structure) Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. Deposit date: 2024-02-22 Release date: 2024-04-17 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
8S54	RNA polymerase II early elongation complex bound to TFIIE and TFIIF - state b (composite structure) Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Zhan, Y, Grabber, F, Oberbeckmann, E, Dienemann, C, Cramer, P. Deposit date: 2024-02-22 Release date: 2024-04-17 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
8S52	RNA polymerase II core initially transcribing complex with an ordered RNA of 10 nt Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. Deposit date: 2024-02-22 Release date: 2024-04-17 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
8S51	RNA polymerase II core initially transcribing complex with an ordered RNA of 8 nt Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. Deposit date: 2024-02-22 Release date: 2024-04-17 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
8RX0	(NEDD8)-CRL2VHL-MZ1-Brd4BD2-Ub(G76S, K48C)-UBE2R1(C93K, S138C, C191S, C223S)-Ub Descriptor: (2~{S},4~{R})-1-[(2~{S})-2-[2-[2-[2-[2-[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]ethanoylamino]ethoxy]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-2,3-dihydro-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Cullin-2, Elongin-B, ... Authors: Crowe, C, Nakasone, M.A. Deposit date: 2024-02-05 Release date: 2024-03-06 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: (NEDD8)-CRL2VHL-MZ1-Brd4BD2-Ub(G76S, K48C)-UBE2R1(C93K, S138C, C191S, C223S)-Ub To Be Published
8RWZ	Open non-crosslinked structure Brd4BD2-MZ1-(NEDD8)-CRL2VHL Descriptor: (2~{S},4~{R})-1-[(2~{S})-2-[2-[2-[2-[2-[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]ethanoylamino]ethoxy]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-2,3-dihydro-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Bromodomain-containing protein 4, Cullin-2, ... Authors: Ciulli, A, Crowe, C, Nakacone, M.A. Deposit date: 2024-02-05 Release date: 2024-03-06 Method: ELECTRON MICROSCOPY (4 Å) Cite: Open non-crosslinked structure Brd4BD2-MZ1-(NEDD8)-CRL2VHL To Be Published
8RU2	Structure of the F-actin barbed end bound by formin mDia1 Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... Authors: Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. Deposit date: 2024-01-29 Release date: 2024-04-10 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.49 Å) Cite: Molecular mechanism of actin filament elongation by formins. Science, 384, 2024
8RTY	Structure of the F-actin barbed end bound by Cdc12 and profilin (ring complex) at a resolution of 6.3 Angstrom Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... Authors: Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. Deposit date: 2024-01-29 Release date: 2024-04-10 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (6.25 Å) Cite: Molecular mechanism of actin filament elongation by formins. Science, 384, 2024
8RTT	Structure of the formin Cdc12 bound to the barbed end of phalloidin-stabilized F-actin. Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... Authors: Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. Deposit date: 2024-01-29 Release date: 2024-04-10 Method: ELECTRON MICROSCOPY (3.56 Å) Cite: Mechanism of formin-mediated processive elongation of actin filaments revealed by cryo-EM To Be Published
8RRR	Alpha-synuclein amyloid fibril Descriptor: Alpha-synuclein Authors: Saibil, H.R, Monistrol, J. Deposit date: 2024-01-23 Release date: 2024-02-28 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Stepwise recruitment of Hsc70 by DNAJB1 produces ordered arrays primed for bursts of amyloid fibre disassembly Biorxiv, 2024

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