8SMH
Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGGAAGTGGG)
Summary for 8SMH
Entry DOI | 10.2210/pdb8smh/pdb |
Descriptor | DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1, ... (5 entities in total) |
Functional Keywords | transcription factor, protein-dna complex, ets family, ets, pu.1, transcription-dna complex, transcription |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 3 |
Total formula weight | 22311.05 |
Authors | Terrell, J.R.,Poon, G.M.K. (deposition date: 2023-04-26, release date: 2023-11-29, Last modification date: 2024-01-17) |
Primary citation | Vernon, T.N.,Terrell, J.R.,Albrecht, A.V.,Germann, M.W.,Wilson, W.D.,Poon, G.M.K. Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors. Structure, 32:83-96.e4, 2024 Cited by PubMed: 38042148DOI: 10.1016/j.str.2023.11.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.37 Å) |
Structure validation
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