8RU2

Structure of the F-actin barbed end bound by formin mDia1

Summary for 8RU2

• Entry DOI: 10.2210/pdb8ru2/pdb
• Related: 8RTT 8RTY 8RU0
• EMDB information: 19496 19497 19499 19501 19503
• Descriptor: Actin, cytoplasmic 1, N-terminally processed, Methylated-DNA--protein-cysteine methyltransferase,Protein diaphanous homolog 1, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: actin, formin, cdc12, profilin, actin assembly, structural protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 299190.30

Authors

Oosterheert, W.,Boiero Sanders, M.,Funk, J.,Prumbaum, D.,Raunser, S.,Bieling, P. (deposition date: 2024-01-29, release date: 2024-04-10, Last modification date: 2024-04-24)

• Primary citation: Oosterheert, W.,Boiero Sanders, M.,Funk, J.,Prumbaum, D.,Raunser, S.,Bieling, P.; Molecular mechanism of actin filament elongation by formins.; Science, 384:eadn9560-eadn9560, 2024; PubMed: 38603491; DOI: 10.1126/science.adn9560

Experimental method

ELECTRON MICROSCOPY (3.49 Å)