PDB: 30548 resultsInfo pagesStatus searchChemie searchBIRD

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8WIC	Cryo- EM structure of Mycobacterium smegmatis 50S ribosomal subunit (body 1) of 70S ribosome, E- tRNA and RafH. Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... Authors: Kumar, N, Sharma, S, Kaushal, P.S. Deposit date: 2023-09-24 Release date: 2024-02-28 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
8WI9	Cryo- EM structure of Mycobacterium smegmatis 30S ribosomal subunit (body 2) of 70S ribosome, bS1 and RafH. Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... Authors: Kumar, N, Sharma, S, Kaushal, P.S. Deposit date: 2023-09-24 Release date: 2024-02-28 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
8WI8	Cryo- EM structure of Mycobacterium smegmatis 50S ribosomal subunit (body 1) of 70S ribosome, bS1 and RafH. Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... Authors: Kumar, N, Sharma, S, Kaushal, P.S. Deposit date: 2023-09-24 Release date: 2024-02-28 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
8WIB	Cryo- EM structure of Mycobacterium smegmatis 70S ribosome, E- tRNA and RafH. Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Kumar, N, Sharma, S, Kaushal, P.S. Deposit date: 2023-09-24 Release date: 2024-02-28 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
8QMO	Cryo-EM structure of the benzo[a]pyrene-bound Hsp90-XAP2-AHR complex Descriptor: ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ... Authors: Kwong, H.S, Grandvuillemin, L, Sirounian, S, Ancelin, A, Lai-Kee-Him, J, Carivenc, C, Lancey, C, Ragan, T.J, Hesketh, E.L, Bourguet, W, Gruszczyk, J. Deposit date: 2023-09-24 Release date: 2024-01-10 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (2.76 Å) Cite: Structural Insights into the Activation of Human Aryl Hydrocarbon Receptor by the Environmental Contaminant Benzo[a]pyrene and Structurally Related Compounds. J.Mol.Biol., 436, 2024
8WHX	Cryo- EM structure of Mycobacterium smegmatis 70S ribosome and RafH. Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Kumar, N, Sharma, S, Kaushal, P.S. Deposit date: 2023-09-23 Release date: 2024-02-28 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
8WHY	Cryo- EM structure of Mycobacterium smegmatis 50S ribosomal subunit (body 1) of 70S ribosome and RafH. Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... Authors: Kumar, N, Sharma, S, Kaushal, P.S. Deposit date: 2023-09-23 Release date: 2024-02-28 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
8QMI	Crystal structure of RNA G2C4 repeats - native model Descriptor: MAGNESIUM ION, RNA (5'-R(*GP*GP*CP*CP*CP*C)-3') Authors: Blaszczyk, L, Kiliszek, A. Deposit date: 2023-09-22 Release date: 2024-05-01 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Antisense RNA C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms a triplex-like structure and binds small synthetic ligand. Nucleic Acids Res., 2024
8QMH	Crystal structure of RNA G2C4 repeats in complex with small synthetic molecule ANP77 Descriptor: 3-(7-azanyl-1,8-naphthyridin-2-yl)-2-[(7-azanyl-1,8-naphthyridin-2-yl)methyl]-~{N}-(3-azanylpropyl)propanamide, CHLORIDE ION, RNA (5'-R(*GP*GP*CP*CP*CP*C)-3') Authors: Kiliszek, A, Ryczek, M, Blaszczyk, L. Deposit date: 2023-09-22 Release date: 2024-05-01 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.1 Å) Cite: Antisense RNA C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms a triplex-like structure and binds small synthetic ligand. Nucleic Acids Res., 2024
8QMA	Structure of the plastid-encoded RNA polymerase complex (PEP) from Sinapis alba Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: do Prado, P.F.V, Ahrens, F.M, Pfannschmidt, T, Hillen, H.S. Deposit date: 2023-09-21 Release date: 2024-03-06 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structure of the multi-subunit chloroplast RNA polymerase. Mol.Cell, 84, 2024
8WG5	Cryo-EM structure of USP16 bound to H2AK119Ub nucleosome Descriptor: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... Authors: Ai, H.S, He, Z.Z, Deng, Z.H, Liu, L. Deposit date: 2023-09-20 Release date: 2023-12-27 Method: ELECTRON MICROSCOPY (3.05 Å) Cite: Cryo-EM structure of USP16 bound to H2AK119Ub nucleosome To Be Published
8QLO	CryoEM structure of the apo SPARTA (BabAgo/TIR-APAZ) complex Descriptor: Short prokaryotic Argonaute, Toll/interleukin-1 receptor domain-containing protein Authors: Finocchio, G, Koopal, B, Potocnik, A, Heijstek, C, Jinek, M, Swarts, D. Deposit date: 2023-09-20 Release date: 2024-01-31 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.57 Å) Cite: Target DNA-dependent activation mechanism of the prokaryotic immune system SPARTA. Nucleic Acids Res., 52, 2024
8QLP	CryoEM structure of the RNA/DNA bound SPARTA (BabAgo/TIR-APAZ) tetrameric complex Descriptor: DNA (5'-D(*AP*CP*TP*AP*AP*TP*AP*GP*AP*TP*TP*AP*GP*AP*GP*CP*CP*GP*TP*C)-3'), MAGNESIUM ION, RNA (5'-R(*AP*UP*GP*AP*CP*GP*GP*CP*UP*CP*UP*AP*AP*UP*CP*UP*AP*UP*UP*AP*GP*U)-3'), ... Authors: Finocchio, G, Koopal, B, Potocnik, A, Heijstek, C, Jinek, M, Swarts, D. Deposit date: 2023-09-20 Release date: 2024-01-31 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.14 Å) Cite: Target DNA-dependent activation mechanism of the prokaryotic immune system SPARTA. Nucleic Acids Res., 52, 2024
8U8J	Co-crystal structure of phosphorylated ERK2 in complex with ERK1/2 inhibitor #16 Descriptor: (4M)-4-{(4R)-3-[(2S)-2-methylbutyl][1,2,4]triazolo[4,3-a]pyridin-7-yl}-N-(1-methyl-1H-pyrazol-5-yl)pyrimidin-2-amine, Mitogen-activated protein kinase 1 Authors: Anderson, J.W, Vigers, G.P. Deposit date: 2023-09-18 Release date: 2024-03-27 Last modified: 2024-04-10 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Conformation selection by ATP-competitive inhibitors and allosteric communication in ERK2. Elife, 12, 2024
8U8K	Co-crystal structure of phosphorylated ERK2 in complex with ERK1/2 inhibitor #8 Descriptor: (4M)-4-{(4S)-3-[(2-chloropyridin-3-yl)methyl][1,2,4]triazolo[4,3-a]pyridin-7-yl}-N-(oxan-4-yl)pyrimidin-2-amine, Mitogen-activated protein kinase 1 Authors: Anderson, J.W, Vigers, G.P. Deposit date: 2023-09-18 Release date: 2024-03-27 Last modified: 2024-04-10 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Conformation selection by ATP-competitive inhibitors and allosteric communication in ERK2. Elife, 12, 2024
8U8O	Human retinal variant phosphomimetic IMPDH1(546)-S477D filament bound by ATP, IMP, and NAD+, octamer-centered Descriptor: ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 1, ... Authors: Calise, S.J, Kollman, J.M. Deposit date: 2023-09-18 Release date: 2024-01-31 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly. J.Cell Biol., 223, 2024
8U8Y	Human retinal variant phosphomimetic IMPDH1(546)-S477D filament bound by ATP, IMP, and NAD+, interface-centered Descriptor: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Calise, S.J, Kollman, J.M. Deposit date: 2023-09-18 Release date: 2024-01-31 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (2.1 Å) Cite: Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly. J.Cell Biol., 223, 2024
8U7M	Human retinal variant phosphomimetic IMPDH1(595)-S477D free octamer bound by GTP, ATP, IMP, and NAD+ Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... Authors: Calise, S.J, Kollman, J.M. Deposit date: 2023-09-15 Release date: 2024-01-31 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly. J.Cell Biol., 223, 2024
8U7V	Human retinal variant phosphomimetic IMPDH1(546)-S477D filament bound by GTP, ATP, IMP, and NAD+, interface-centered Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... Authors: Calise, S.J, Kollman, J.M. Deposit date: 2023-09-15 Release date: 2024-01-31 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly. J.Cell Biol., 223, 2024
8U7Q	Human retinal variant phosphomimetic IMPDH1(546)-S477D filament bound by GTP, ATP, IMP, and NAD+, octamer-centered Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... Authors: Calise, S.J, Kollman, J.M. Deposit date: 2023-09-15 Release date: 2024-01-31 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly. J.Cell Biol., 223, 2024
8WD5	Crystal structure of farnesyl diphosphate synthase FPPS1 from silkworm, Bombyx mori Descriptor: Farnesyl pyrophosphate synthase, GLYCEROL Authors: Guo, P.C, Fang, H. Deposit date: 2023-09-14 Release date: 2024-05-22 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural Insights into the Substrate Binding of Farnesyl Diphosphate Synthase FPPS1 from Silkworm, Bombyx mori. J.Agric.Food Chem., 72, 2024
8QKB	Crystal structure of human cathepsin L in complex with the vinyl sulfone inhibitor K777 Descriptor: 1,2-ETHANEDIOL, Cathepsin L, DI(HYDROXYETHYL)ETHER, ... Authors: Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. Deposit date: 2023-09-14 Release date: 2023-09-27 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors. J.Med.Chem., 67, 2024
8WCS	Cryo-EM structure of Cas13h1-crRNA binary complex Descriptor: 66-nt crRNA, Cas13h1, MAGNESIUM ION Authors: Zhang, C. Deposit date: 2023-09-13 Release date: 2024-05-22 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Molecular mechanism for target RNA recognition and cleavage of Cas13h. Nucleic Acids Res., 2024
8U60	Structure of Mango II variant2 aptamer bound to T01-6A Descriptor: 2-[(~{E})-[6-(4-methoxyphenyl)-1-methyl-quinolin-4-ylidene]methyl]-3-methyl-1,3-benzothiazole, POTASSIUM ION, RNA Mango II variant 2 aptamer Authors: Passalacqua, L.F.M, Ferre-D'Amare, A.R. Deposit date: 2023-09-13 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structure of Mango II variant2 aptamer bound to T01-6A To Be Published
8U5Z	Structure of Mango II variant aptamer bound to T01-7M-B Descriptor: 2-[(E)-(1,7-dimethylquinolin-4(1H)-ylidene)methyl]-3-{2,16-dioxo-20-[(3aR,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-6,9,12-trioxa-3,15-diazaicosan-1-yl}-1,3-benzothiazol-3-ium, Mango II variant, POTASSIUM ION, ... Authors: Passalacqua, L.F.M, Ferre-D'Amare, A.R. Deposit date: 2023-09-13 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of Mango II variant aptamer bound to T01-7M-B To Be Published

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