PDB: 1932 件ウェブページステータス検索Chemie searchBIRD

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1S49	Crystal Structure of RNA-dependent RNA polymerase construct 1 (residues 71-679) from bovine viral diarrhea virus complexed with GTP 分子名称: GUANOSINE-5'-TRIPHOSPHATE, RNA-dependent RNA polymerase 著者 Choi, K.H, Groarke, J.M, Young, D.C, Kuhn, R.J, Smith, J.L, Pevear, D.C, Rossmann, M.G. 登録日 2004-01-15 公開日 2004-04-06 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation. Proc.Natl.Acad.Sci.Usa, 101, 2004
4LQ9	Crystal structure of human norovirus RNA-dependent RNA-polymerase in complex with NAF2 分子名称: MAGNESIUM ION, RNA-dependent RNA-polymerase, naphthalene-1,5-disulfonic acid 著者 Milani, M, Tarantino, D, Mastrangelo, E, Croci, R. 登録日 2013-07-17 公開日 2014-02-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Naphthalene-sulfonate inhibitors of human norovirus RNA-dependent RNA-polymerase. Antiviral Res., 102, 2014
4LQ3	Crystal structure of human norovirus RNA-dependent RNA-polymerase bound to the inhibitor PPNDS 分子名称: 3-[(E)-{4-formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]pyridin-2-yl}diazenyl]-7-nitronaphthalene-1,5-disulfonic acid, 5'-R(P*GP*G)-3', MAGNESIUM ION, ... 著者 Milani, M, Tarantino, D, Mastrangelo, E, Croci, R. 登録日 2013-07-17 公開日 2014-02-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Naphthalene-sulfonate inhibitors of human norovirus RNA-dependent RNA-polymerase. Antiviral Res., 102, 2014
4WFZ	Coxsackievirus B3 3Dpol RNA Dependent RNA Polymerase - NaCl Crystal Form 分子名称: RNA-directed RNA polymerase, SODIUM ION 著者 Peersen, O.B, McDonald, S.M. 登録日 2014-09-17 公開日 2014-10-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.803 Å) 主引用文献 Structure-Function Relationships Underlying the Replication Fidelity of Viral RNA-Dependent RNA Polymerases. J.Virol., 89, 2015
4WFX	Coxsackievirus B3 Polymerase - F232L Mutant - NaCl Crystal Form 分子名称: RNA-directed RNA polymerase, SODIUM ION 著者 Peersen, O.B, McDonald, S.M. 登録日 2014-09-17 公開日 2014-10-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.808 Å) 主引用文献 Structure-Function Relationships Underlying the Replication Fidelity of Viral RNA-Dependent RNA Polymerases. J.Virol., 89, 2015
2CKW	The 2.3 A resolution structure of the Sapporo virus RNA dependant RNA polymerase. 分子名称: RNA-DIRECTED RNA POLYMERASE 著者 Fullerton, S.W.B, Tucker, P.A, Rohayem, J, Coutard, B, Gebhardt, J, Gorbalenya, A, Canard, B. 登録日 2006-04-24 公開日 2006-11-29 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and Functional Characterization of Sapovirus RNA-Dependent RNA Polymerase. J.Virol., 81, 2007
2JL9	Structural explanation for the role of Mn in the activity of phi6 RNA- dependent RNA polymerase 分子名称: RNA-DIRECTED RNA POLYMERASE 著者 Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M. 登録日 2008-09-05 公開日 2008-11-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase. Nucleic Acids Res., 36, 2008
2IJF	Crystal Structure of the Poliovirus RNA-Dependent RNA Polymerase Fidelity Mutant 3Dpol G64S 分子名称: RNA-directed RNA polymerase 著者 Marcotte, L.L, Gohara, D.G, Filman, D.J, Hogle, J.M. 登録日 2006-09-29 公開日 2007-02-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of poliovirus 3CD: virally-encoded protease and precursor to the RNA-dependent RNA polymerase. J.Virol., 81, 2007
2EC0	RNA-dependent RNA polymerase of foot-and-mouth disease virus in complex with a template-primer RNA and ATP 分子名称: 5'-R(*GP*GP*GP*CP*CP*CP*A)-3', 5'-R(P*AP*UP*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... 著者 Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. 登録日 2007-02-09 公開日 2007-06-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Sequential structures provide insights into the fidelity of RNA replication Proc.Natl.Acad.Sci.Usa, 104, 2007
2D7S	Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with VPg protein 分子名称: RNA-dependent RNA polymerase, VPg1 protein 著者 Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. 登録日 2005-11-29 公開日 2006-03-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structure of a protein primer-polymerase complex in the initiation of genome replication Embo J., 25, 2006
7W84	CryoEM structure of apo form ZmRDR2 at 3.4 Angstroms resolution 分子名称: RNA-dependent RNA polymerase 著者 Du, X, Yang, Z, Du, J. 登録日 2021-12-07 公開日 2022-06-08 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure of plant RNA-DEPENDENT RNA POLYMERASE 2, an enzyme involved in small interfering RNA production. Plant Cell, 34, 2022
7W88	CryoEM structure of open form ZmRDR2 at 3.5 Angstroms resolution 分子名称: RNA-dependent RNA polymerase 著者 Du, X, Yang, Z, Du, J. 登録日 2021-12-07 公開日 2022-06-08 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of plant RNA-DEPENDENT RNA POLYMERASE 2, an enzyme involved in small interfering RNA production. Plant Cell, 34, 2022
7W82	Crystal structure of maize RDR2 分子名称: RNA-dependent RNA polymerase 著者 Du, X, Yang, Z, Du, J. 登録日 2021-12-07 公開日 2022-06-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of plant RNA-DEPENDENT RNA POLYMERASE 2, an enzyme involved in small interfering RNA production. Plant Cell, 34, 2022
1CSJ	CRYSTAL STRUCTURE OF THE RNA-DEPENDENT RNA POLYMERASE OF HEPATITIS C VIRUS 分子名称: HEPATITIS C VIRUS RNA POLYMERASE (NS5B) 著者 Bressanelli, S, Tomei, L, Roussel, A, Incitti, I, Vitale, R.L, Mathieu, M, De Francesco, R, Rey, F.A. 登録日 1999-08-18 公開日 1999-11-08 最終更新日 2013-02-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus. Proc.Natl.Acad.Sci.USA, 96, 1999
4WFY	Coxsackievirus B3 Polymerase - F232L Mutant - AmSO4 Crystal Form 分子名称: GLYCEROL, RNA-directed RNA polymerase, SULFATE ION 著者 Peersen, O.B, McDonald, S.M. 登録日 2014-09-17 公開日 2014-10-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Structure-Function Relationships Underlying the Replication Fidelity of Viral RNA-Dependent RNA Polymerases. J.Virol., 89, 2015
7AAP	Nsp7-Nsp8-Nsp12 SARS-CoV2 RNA-dependent RNA polymerase in complex with template:primer dsRNA and favipiravir-RTP 分子名称: MAGNESIUM ION, Non-structural protein 12, Non-structural protein 7, ... 著者 Naydenova, K, Muir, K.W, Wu, L.F, Zhang, Z, Coscia, F, Peet, M, Castro-Hartman, P, Qian, P, Sader, K, Dent, K, Kimanius, D, Sutherland, J.D, Lowe, J, Barford, D, Russo, C.J. 登録日 2020-09-04 公開日 2020-09-23 最終更新日 2023-04-19 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP. Proc.Natl.Acad.Sci.USA, 118, 2021
8FPJ	Co-structure of the Human Metapneunomovirus RNA-dependent RNA polymerase with MRK-1 分子名称: 4-(2-aminopropan-2-yl)-N'-[4-(cyclopropyloxy)-3-methoxybenzoyl]-6-(4-fluorophenyl)pyridine-2-carbohydrazide, Phosphoprotein, RNA-directed RNA polymerase L 著者 Fischmann, T.O. 登録日 2023-01-04 公開日 2023-06-14 最終更新日 2023-07-05 実験手法 ELECTRON MICROSCOPY (2.74 Å) 主引用文献 Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases. Commun Biol, 6, 2023
8FPI	Co-structure of the Respiratory Syncytial Virus RNA-dependent RNA polymerase with MRK-1 分子名称: 4-(2-aminopropan-2-yl)-N'-[4-(cyclopropyloxy)-3-methoxybenzoyl]-6-(4-fluorophenyl)pyridine-2-carbohydrazide, Phosphoprotein, RNA-directed RNA polymerase L 著者 Fischmann, T.O. 登録日 2023-01-04 公開日 2023-06-14 最終更新日 2023-07-05 実験手法 ELECTRON MICROSCOPY (2.39 Å) 主引用文献 Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases. Commun Biol, 6, 2023
4GZK	Structure and interactions of the RNA-dependent RNA polymerase from bacteriophage phi12 分子名称: FORMIC ACID, MAGNESIUM ION, RNA-dependent RNA polymerase P2 著者 Ren, Z, Franklin, M, Ghose, R. 登録日 2012-09-06 公開日 2013-07-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Structure of the RNA-directed RNA Polymerase from the cystovirus 12. Proteins, 81, 2013
2JLF	STRUCTURAL EXPLANATION FOR THE ROLE OF MN IN THE ACTIVITY OF PHI6 RNA- DEPENDENT RNA POLYMERASE 分子名称: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE 著者 Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M. 登録日 2008-09-08 公開日 2008-11-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase. Nucleic Acids Res., 36, 2008
1XR6	Crystal Structure of RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 1B 分子名称: Genome polyprotein, POTASSIUM ION 著者 Love, R.A, Maegley, K.A, Yu, X, Ferre, R.A, Lingardo, L.K, Diehl, W, Parge, H.E, Dragovich, P.S, Fuhrman, S.A. 登録日 2004-10-13 公開日 2004-10-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual-Function Target for Common Cold Antiviral Therapy Structure, 12, 2004
1XR7	Crystal structure of RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 16 分子名称: Genome polyprotein 著者 Love, R.A, Maegley, K.A, Yu, X, Ferre, R.A, Lingardo, L.K, Diehl, W, Parge, H.E, Dragovich, P.S, Fuhrman, S.A. 登録日 2004-10-13 公開日 2004-10-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual-Function Target for Common Cold Antiviral Therapy Structure, 12, 2004
1XR5	Crystal Structure of the RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 14 分子名称: Genome polyprotein, SAMARIUM (III) ION 著者 Love, R.A, Maegley, K.A, Yu, X, Ferre, R.A, Lingardo, L.K, Diehl, W, Parge, H.E, Dragovich, P.S, Fuhrman, S.A. 登録日 2004-10-13 公開日 2004-10-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual-Function Target for Common Cold Antiviral Therapy Structure, 12, 2004
7BV1	Cryo-EM structure of the apo nsp12-nsp7-nsp8 complex 分子名称: Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase, ... 著者 Yin, W, Mao, C, Luan, X, Shen, D, Shen, Q, Su, H, Wang, X, Zhou, F, Zhao, W, Gao, M, Chang, S, Xie, Y.C, Tian, G, Jiang, H.W, Tao, S.C, Shen, J, Jiang, Y, Jiang, H, Xu, Y, Zhang, S, Zhang, Y, Xu, H.E. 登録日 2020-04-09 公開日 2020-04-22 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. Science, 368, 2020
7BV2	The nsp12-nsp7-nsp8 complex bound to the template-primer RNA and triphosphate form of Remdesivir(RTP) 分子名称: MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ... 著者 Yin, W, Mao, C, Luan, X, Shen, D, Shen, Q, Su, H, Wang, X, Zhou, F, Zhao, W, Gao, M, Chang, S, Xie, Y.C, Tian, G, Jiang, H.W, Tao, S.C, Shen, J, Jiang, Y, Jiang, H, Xu, Y, Zhang, S, Zhang, Y, Xu, H.E. 登録日 2020-04-09 公開日 2020-04-22 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. Science, 368, 2020

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