1XR7
Crystal structure of RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 16
Replaces: 1TE9Summary for 1XR7
Entry DOI | 10.2210/pdb1xr7/pdb |
Related | 1TE8 1TE9 1TEB 1XR5 1XR6 |
Descriptor | Genome polyprotein (2 entities in total) |
Functional Keywords | rna-dependent rna polymerase, transferase |
Biological source | Human rhinovirus 16 |
Cellular location | Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): Q82122 |
Total number of polymer chains | 2 |
Total formula weight | 104572.00 |
Authors | Love, R.A.,Maegley, K.A.,Yu, X.,Ferre, R.A.,Lingardo, L.K.,Diehl, W.,Parge, H.E.,Dragovich, P.S.,Fuhrman, S.A. (deposition date: 2004-10-13, release date: 2004-10-26, Last modification date: 2024-02-14) |
Primary citation | Love, R.A.,Maegley, K.A.,Yu, X.,Ferre, R.A.,Lingardo, L.K.,Diehl, W.,Parge, H.E.,Dragovich, P.S.,Fuhrman, S.A. The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual-Function Target for Common Cold Antiviral Therapy Structure, 12:1533-1544, 2004 Cited by PubMed: 15296746DOI: 10.1016/j.str.2004.05.024 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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