7AAP

Nsp7-Nsp8-Nsp12 SARS-CoV2 RNA-dependent RNA polymerase in complex with template:primer dsRNA and favipiravir-RTP

Summary for 7AAP

• Entry DOI: 10.2210/pdb7aap/pdb
• EMDB information: 11692
• Descriptor: Non-structural protein 12, Non-structural protein 8, Non-structural protein 7, ... (9 entities in total)
• Functional Keywords: rna-dependent rna polymerase, favipiravir, sars-cov2, ncovid19, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 6
• Total formula weight: 181600.83

Authors

Naydenova, K.,Muir, K.W.,Wu, L.F.,Zhang, Z.,Coscia, F.,Peet, M.,Castro-Hartman, P.,Qian, P.,Sader, K.,Dent, K.,Kimanius, D.,Sutherland, J.D.,Lowe, J.,Barford, D.,Russo, C.J. (deposition date: 2020-09-04, release date: 2020-09-23, Last modification date: 2023-04-19)

• Primary citation: Naydenova, K.,Muir, K.W.,Wu, L.F.,Zhang, Z.,Coscia, F.,Peet, M.J.,Castro-Hartmann, P.,Qian, P.,Sader, K.,Dent, K.,Kimanius, D.,Sutherland, J.D.,Lowe, J.,Barford, D.,Russo, C.J.; Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP.; Proc.Natl.Acad.Sci.USA, 118:-, 2021; PubMed: 33526596; DOI: 10.1073/pnas.2021946118

Experimental method

ELECTRON MICROSCOPY (2.5 Å)