7AAP
Nsp7-Nsp8-Nsp12 SARS-CoV2 RNA-dependent RNA polymerase in complex with template:primer dsRNA and favipiravir-RTP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Non-structural protein 12 | polymer | 967 | 110521.9 | 1 | UniProt (P0DTD1) Pfam (PF06478) Pfam (PF00680) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | Non-structural protein 12 |
| 2 | B, D (B, D) | Non-structural protein 8 | polymer | 198 | 21903.0 | 2 | UniProt (P0DTD1) Pfam (PF08717) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | Non-structural protein 8 |
| 3 | C (C) | Non-structural protein 7 | polymer | 83 | 9248.8 | 1 | UniProt (P0DTD1) Pfam (PF08716) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | Non-structural protein 7 |
| 4 | E (P) | RNA (5'-R(P*UP*UP*AP*AP*GP*UP*UP*AP*U)-3') | polymer | 24 | 7696.6 | 1 | Severe acute respiratory syndrome coronavirus 2 | ||
| 5 | F (T) | RNA (5'-R(P*UP*UP*CP*AP*UP*AP*AP*CP*UP*UP*AP*A)-3') | polymer | 30 | 9418.6 | 1 | Severe acute respiratory syndrome coronavirus 2 | ||
| 6 | G, H (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 7 | I, J, L (A, P) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 8 | K (A) | PYROPHOSPHATE 2- | non-polymer | 176.0 | 1 | Chemie (POP) | |||
| 9 | M (T) | [[(2~{R},3~{S},4~{R},5~{R})-5-(3-aminocarbonyl-5-fluoranyl-2-oxidanylidene-pyrazin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | non-polymer | 529.2 | 1 | Chemie (GE6) |
Sequence modifications
A: 1 - 932 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Glu 933 | - | expression tag |
| Asn 934 | - | expression tag |
| Leu 935 | - | expression tag |
| Tyr 936 | - | expression tag |
| Phe 937 | - | expression tag |
| Gln 938 | - | expression tag |
| Ser 939 | - | expression tag |
| Trp 940 | - | expression tag |
| Ser 941 | - | expression tag |
| His 942 | - | expression tag |
| Pro 943 | - | expression tag |
| Gln 944 | - | expression tag |
| Phe 945 | - | expression tag |
| Glu 946 | - | expression tag |
| Lys 947 | - | expression tag |
| Gly 948 | - | expression tag |
| Gly 949 | - | expression tag |
| Gly 950 | - | expression tag |
| Ser 951 | - | expression tag |
| Gly 952 | - | expression tag |
| Gly 953 | - | expression tag |
| Gly 954 | - | expression tag |
| Ser 955 | - | expression tag |
| Gly 956 | - | expression tag |
| Gly 957 | - | expression tag |
| Gly 958 | - | expression tag |
| Ser 959 | - | expression tag |
| Trp 960 | - | expression tag |
| Ser 961 | - | expression tag |
| His 962 | - | expression tag |
| Pro 963 | - | expression tag |
| Gln 964 | - | expression tag |
| Phe 965 | - | expression tag |
| Glu 966 | - | expression tag |
| Lys 967 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 180692.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 908.8 | |
| All* | Total formula weight | 181600.8 |
