PDB: 54 resultsInfo pagesStatus searchChemie searchBIRD

---

1HU0	CRYSTAL STRUCTURE OF AN HOGG1-DNA BOROHYDRIDE TRAPPED INTERMEDIATE COMPLEX Descriptor: 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 8-OXOGUANINE, ... Authors: Fromme, J.C, Bruner, S.D, Yang, W, Karplus, M, Verdine, G.L. Deposit date: 2001-01-03 Release date: 2003-02-25 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Product-Assisted Catalysis in base-excision DNA Repair Nat.Struct.Biol., 10, 2003
3I0X	Crystal structure of Clostridium acetobutylicum 8-oxoguanine glycosylase/lyase in complex with dsDNA containing adenine opposite to 8-oxoG Descriptor: 5'-D(*AP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*AP*TP*GP*GP*A)-3', 8-oxoguanine-DNA-glycosylase, ... Authors: Faucher, F, Doublie, S. Deposit date: 2009-06-25 Release date: 2009-09-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural basis for the lack of opposite base specificity of Clostridium acetobutylicum 8-oxoguanine DNA glycosylase. Dna Repair, 8, 2009
3I0W	Crystal structure of Clostridium acetobutylicum 8-oxoguanine glycosylase/lyase in complex with dsDNA containing cytosine opposite to 8-oxoG Descriptor: 1,2-ETHANEDIOL, 5'-D(*AP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*A)-3', ... Authors: Faucher, F, Doublie, S. Deposit date: 2009-06-25 Release date: 2009-09-29 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Structural basis for the lack of opposite base specificity of Clostridium acetobutylicum 8-oxoguanine DNA glycosylase. Dna Repair, 8, 2009
3IH7	Crystal structure of catalytically active human 8-oxoguanine glycosylase distally crosslinked to guanine-containing DNA Descriptor: 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3', 5'-D(AP*TP*CP*TP*GP*GP*AP*CP*CP*TP*GP*CP*A)-3', N-glycosylase/DNA lyase Authors: Verdine, G.L, Crenshaw, C.M, Oo, K.S, Kutchukian, P.S. Deposit date: 2009-07-29 Release date: 2010-11-03 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.1 Å) Cite: A Catalytic Checkpoint in Base Excision by the Human 8-Oxoguanine DNA Glycosylase hOGG1 To be Published
3KTU	Structure of human 8-oxoGuanine Glycosylase 1 bound to fluorninated oxoG-containing DNA Descriptor: CALCIUM ION, DNA (5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*CP*AP*(FDG)P*GP*TP*CP*TP*AP*C)-3'), ... Authors: Verdine, G.L, Lee, S.M. Deposit date: 2009-11-26 Release date: 2010-07-14 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural investigation of hOGG1 bound to a fluorinated oxoG analog to be published
1YQM	Catalytically inactive human 8-oxoguanine glycosylase crosslinked to 7-deazaguanine containing DNA Descriptor: 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*CP*AP*(7GU)P*GP*TP*CP*TP*AP*C)-3', CALCIUM ION, ... Authors: Banerjee, A, Yang, W, Karplus, M, Verdine, G.L. Deposit date: 2005-02-02 Release date: 2005-04-05 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature, 434, 2005
1YQK	Human 8-oxoguanine glycosylase crosslinked with guanine containing DNA Descriptor: 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*G)-3', 5'-D(P*CP*AP*GP*GP*TP*CP*TP*AP*C)-3', CALCIUM ION, ... Authors: Banerjee, A, Yang, W, Karplus, M, Verdine, G.L. Deposit date: 2005-02-01 Release date: 2005-04-05 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature, 434, 2005
1YQR	Catalytically inactive human 8-oxoguanine glycosylase crosslinked to oxoG containing DNA Descriptor: 5'-D(P*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3', CALCIUM ION, ... Authors: Banerjee, A, Yang, W, Karplus, M, Verdine, G.L. Deposit date: 2005-02-02 Release date: 2005-04-05 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.43 Å) Cite: Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature, 434, 2005
1YQL	Catalytically inactive hOGG1 crosslinked with 7-deaza-8-azaguanine containing DNA Descriptor: 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*CP*AP*(PPW)P*GP*TP*CP*TP*AP*C)-3', CALCIUM ION, ... Authors: Banerjee, A, Yang, W, Karplus, M, Verdine, G.L. Deposit date: 2005-02-02 Release date: 2005-04-05 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature, 434, 2005
7ZC7	Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH012941 Descriptor: 2-[4-(3,5-dimethylpyrazol-1-yl)phenyl]-~{N}-(4,5,6,7-tetrahydro-1,2-benzoxazol-3-yl)ethanamide, N-glycosylase/DNA lyase, NICKEL (II) ION Authors: Davies, J.R, Scaletti, E, Stenmark, P. Deposit date: 2022-03-25 Release date: 2023-07-05 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH012941 To Be Published
7Z5R	Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH012035 Descriptor: (7~{R})-~{N}-(4,5,6,7-tetrahydro-1,2-benzoxazol-3-yl)bicyclo[4.2.0]octa-1,3,5-triene-7-carboxamide, N-glycosylase/DNA lyase, NICKEL (II) ION Authors: Davies, J.R, Scaletti, E, Stenmark, P. Deposit date: 2022-03-09 Release date: 2023-03-22 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH012035 To Be Published
7Z3Y	Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH013545 Descriptor: 2-[4-(3,5-dimethylpyrazol-1-yl)-2,6-bis(fluoranyl)phenyl]-~{N}-(4,5,6,7-tetrahydro-1,2-benzoxazol-3-yl)ethanamide, GLYCEROL, N-glycosylase/DNA lyase, ... Authors: Scaletti, E.R, Stenmark, P. Deposit date: 2022-03-02 Release date: 2023-03-22 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH013545 To Be Published
7Z5B	Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH013546 Descriptor: 2-[4-(2,4-dimethyl-1~{H}-imidazol-5-yl)phenyl]-~{N}-(4,5,6,7-tetrahydro-1,2-benzoxazol-3-yl)ethanamide, N-glycosylase/DNA lyase, NICKEL (II) ION Authors: Scaletti, E, Stenmark, P. Deposit date: 2022-03-08 Release date: 2023-03-22 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH013546 To Be Published
7ZG3	Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH011228 Descriptor: N-glycosylase/DNA lyase, NICKEL (II) ION, ~{N}-[(1~{S})-1,2,2-trimethylcyclopropyl]pyrrolo[1,2-c]pyrimidine-3-carboxamide Authors: Davies, J.R, Scaletti, E, Stenmark, P. Deposit date: 2022-04-01 Release date: 2023-08-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH011228 To Be Published
2NOH	Structure of catalytically inactive Q315A human 8-oxoguanine glycosylase complexed to 8-oxoguanine DNA Descriptor: 5'-D(*GP*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... Authors: Radom, C.T, Banerjee, A, Verdine, G.L. Deposit date: 2006-10-25 Release date: 2006-11-21 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations. J.Biol.Chem., 282, 2007
2NOZ	Structure of Q315F human 8-oxoguanine glycosylase distal crosslink to 8-oxoguanine DNA Descriptor: 5'-D(*G*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*G*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... Authors: Radom, C.T, Banerjee, A, Verdine, G.L. Deposit date: 2006-10-26 Release date: 2006-11-21 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.43 Å) Cite: Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations. J.Biol.Chem., 282, 2007
2NOI	Structure of G42A human 8-oxoguanine glycosylase crosslinked to undamaged G-containing DNA Descriptor: 5'-D(*GP*CP*GP*TP*C*CP*AP*GP*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... Authors: Radom, C.T, Banerjee, A, Verdine, G.L. Deposit date: 2006-10-25 Release date: 2006-11-21 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations. J.Biol.Chem., 282, 2007
2NOF	Structure of Q315F human 8-oxoguanine glycosylase proximal crosslink to 8-oxoguanine DNA Descriptor: 5'-D(*GP*CP*GP*TP*C*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... Authors: Radom, C.T, Banerjee, A, Verdine, G.L. Deposit date: 2006-10-25 Release date: 2006-11-21 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations. J.Biol.Chem., 282, 2007
2NOB	Structure of catalytically inactive H270A human 8-oxoguanine glycosylase crosslinked to 8-oxoguanine DNA Descriptor: 5'-D(*G*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*T*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... Authors: Radom, C.T, Banerjee, A, Verdine, G.L. Deposit date: 2006-10-25 Release date: 2006-11-21 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations. J.Biol.Chem., 282, 2007
2NOE	Structure of catalytically inactive G42A human 8-oxoguanine glycosylase complexed to 8-oxoguanine DNA Descriptor: 5'-D(*G*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*G*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... Authors: Radom, C.T, Banerjee, A, Verdine, G.L. Deposit date: 2006-10-25 Release date: 2006-11-21 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations. J.Biol.Chem., 282, 2007
1KO9	Native Structure of the Human 8-oxoguanine DNA Glycosylase hOGG1 Descriptor: 8-oxoguanine DNA glycosylase, SULFATE ION Authors: Bjoras, M, Seeberg, E, Luna, L, Pearl, L.H, Barrett, T.E. Deposit date: 2001-12-20 Release date: 2002-01-09 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Reciprocal "flipping" underlies substrate recognition and catalytic activation by the human 8-oxo-guanine DNA glycosylase. J.Mol.Biol., 317, 2002
1LWW	Borohydride-trapped hOgg1 Intermediate Structure Co-Crystallized with 8-bromoguanine Descriptor: 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 8-BROMOGUANINE, ... Authors: Fromme, J.C, Bruner, S.D, Yang, W, Karplus, M, Verdine, G.L. Deposit date: 2002-06-03 Release date: 2003-02-25 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Product-Assisted Catalysis in Base Excision DNA Repair Nat.Struct.Biol., 10, 2003
1M3H	Crystal Structure of Hogg1 D268E Mutant with Product Oligonucleotide Descriptor: 5'-D(P*GP*CP*GP*TP*CP*CP*AP*(DDX))-3', 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(P*GP*TP*CP*TP*AP*CP*C)-3', ... Authors: Chung, S.J, Verdine, G.L. Deposit date: 2002-06-27 Release date: 2004-04-20 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structures of End Products Resulting from Lesion Processing by a DNA Glycosylase/Lyase Chem.Biol., 11, 2004
1LWV	Borohydride-trapped hOgg1 Intermediate Structure Co-Crystallized with 8-aminoguanine Descriptor: 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 8-AMINOGUANINE, ... Authors: Fromme, J.C, Bruner, S.D, Yang, W, Karplus, M, Verdine, G.L. Deposit date: 2002-06-03 Release date: 2003-02-25 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Product-Assisted Catalysis in Base Excision DNA Repair Nat.Struct.Biol., 10, 2003
1LWY	hOgg1 Borohydride-Trapped Intermediate without 8-oxoguanine Descriptor: 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 8-OXOGUANINE DNA GLYCOSYLASE Authors: Fromme, J.C, Bruner, S.D, Yang, W, Karplus, M, Verdine, G.L. Deposit date: 2002-06-03 Release date: 2003-02-25 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Product-Assisted Catalysis in Base Excision DNA Repair Nat.Struct.Biol., 10, 2003

<123>