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2NOH

Structure of catalytically inactive Q315A human 8-oxoguanine glycosylase complexed to 8-oxoguanine DNA

Summary for 2NOH
Entry DOI10.2210/pdb2noh/pdb
Related1EBM 1KO9 2NOB 2NOE 2NOF 2NOI 2NOL 2NOZ
Descriptor5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*GP*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', N-glycosylase/DNA lyase, ... (5 entities in total)
Functional Keywordsn-glycosylase/dna lyase, dna repair, 8-oxoguanine, hydrolase, lyase-dna complex, lyase/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus, nucleoplasm . Isoform 1A: Nucleus. Isoform 2A: Mitochondrion: O15527
Total number of polymer chains3
Total formula weight45760.36
Authors
Radom, C.T.,Banerjee, A.,Verdine, G.L. (deposition date: 2006-10-25, release date: 2006-11-21, Last modification date: 2023-12-27)
Primary citationRadom, C.T.,Banerjee, A.,Verdine, G.L.
Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.
J.Biol.Chem., 282:9182-9194, 2007
Cited by
PubMed: 17114185
DOI: 10.1074/jbc.M608989200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.01 Å)
Structure validation

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