1LWW
Borohydride-trapped hOgg1 Intermediate Structure Co-Crystallized with 8-bromoguanine
Summary for 1LWW
Entry DOI | 10.2210/pdb1lww/pdb |
Related | 1EBM 1FN7 1HU0 1LWV 1LWY |
Descriptor | 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 8-OXOGUANINE DNA GLYCOSYLASE, ... (6 entities in total) |
Functional Keywords | dna repair, dna glycosylase, protein/dna, borohydride, covalent trapping, product-assisted catalysis, reaction intermediate, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus, nucleoplasm. Isoform 1A: Nucleus. Isoform 2A: Mitochondrion: O15527 |
Total number of polymer chains | 3 |
Total formula weight | 45698.14 |
Authors | Fromme, J.C.,Bruner, S.D.,Yang, W.,Karplus, M.,Verdine, G.L. (deposition date: 2002-06-03, release date: 2003-02-25, Last modification date: 2011-07-13) |
Primary citation | Fromme, J.C.,Bruner, S.D.,Yang, W.,Karplus, M.,Verdine, G.L. Product-Assisted Catalysis in Base Excision DNA Repair Nat.Struct.Biol., 10:204-211, 2003 Cited by PubMed: 12592398DOI: 10.1038/nsb902 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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