1EBM
CRYSTAL STRUCTURE OF THE HUMAN 8-OXOGUANINE GLYCOSYLASE (HOGG1) BOUND TO A SUBSTRATE OLIGONUCLEOTIDE
Summary for 1EBM
Entry DOI | 10.2210/pdb1ebm/pdb |
Descriptor | DNA (5'-D(*GP*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3'), 8-OXOGUANINE DNA GLYCOSYLASE, ... (5 entities in total) |
Functional Keywords | dna repair, dna glycosylase, protein/dna, lyase-dna complex, lyase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus, nucleoplasm. Isoform 1A: Nucleus. Isoform 2A: Mitochondrion: O15527 |
Total number of polymer chains | 3 |
Total formula weight | 44884.29 |
Authors | Bruner, S.D.,Norman, D.P.,Verdine, G.L. (deposition date: 2000-01-24, release date: 2000-03-20, Last modification date: 2024-02-07) |
Primary citation | Bruner, S.D.,Norman, D.P.,Verdine, G.L. Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA. Nature, 403:859-866, 2000 Cited by PubMed: 10706276DOI: 10.1038/35002510 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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