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7Z5R

Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH012035

Summary for 7Z5R
Entry DOI10.2210/pdb7z5r/pdb
DescriptorN-glycosylase/DNA lyase, (7~{R})-~{N}-(4,5,6,7-tetrahydro-1,2-benzoxazol-3-yl)bicyclo[4.2.0]octa-1,3,5-triene-7-carboxamide, NICKEL (II) ION, ... (4 entities in total)
Functional Keywordsogg1, glycosylase, inhibitor, dna binding protein
Biological sourceMus musculus (house mouse)
Total number of polymer chains3
Total formula weight108313.58
Authors
Davies, J.R.,Scaletti, E.,Stenmark, P. (deposition date: 2022-03-09, release date: 2023-03-22, Last modification date: 2024-02-07)
Primary citationDavies, J.R.,Scaletti, E.,Stenmark, P.
Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH012035
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

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