8TE6
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8TE5
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8RPB
| Structure of S79 Fab in complex with IgV domain of human PD-L1 | Descriptor: | CHLORIDE ION, GLYCEROL, Programmed cell death 1 ligand 1, ... | Authors: | Svensson, A, Kelpsas, V, Laursen, M, Rose, N. | Deposit date: | 2024-01-15 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.794 Å) | Cite: | Structural analysis of light chain-driven bispecific antibodies targeting CD47 and PD-L1. Mabs, 16, 2024
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8JBA
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8U0Y
| Bacterial protein cpx | Descriptor: | Fluorescent protein, PHYCOUROBILIN, Receptor A, ... | Authors: | Gully, B.S, Rossjohn, J. | Deposit date: | 2023-08-29 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Bacterial protein cpx To Be Published
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8U31
| Crystal structure of PD-1 in complex with a Fab | Descriptor: | Fab heavy chain, Fab light chain, GLYCEROL, ... | Authors: | Sun, D, Masureel, M. | Deposit date: | 2023-09-07 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability. Mabs, 16, 2024
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8U32
| Crystal structure of PD-1 in complex with a Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ... | Authors: | Sun, D, Masureel, M. | Deposit date: | 2023-09-07 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability. Mabs, 16, 2024
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8JEL
| Crystal structure of TIGIT in complexed with Ociperlimab, crystal form I | Descriptor: | T-cell immunoreceptor with Ig and ITIM domains, antibody heavy chain, antibody light chain | Authors: | Sun, J, Zhang, X.X, Song, J. | Deposit date: | 2023-05-16 | Release date: | 2024-02-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab. Structure, 32, 2024
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8JEO
| Crystal structure of TIGIT in complexed with Tiragolumab | Descriptor: | T-cell immunoreceptor with Ig and ITIM domains, antibody heavy chain, antibody light chain | Authors: | Sun, J, Zhang, X.X, Song, J. | Deposit date: | 2023-05-16 | Release date: | 2024-02-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab. Structure, 32, 2024
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8JEN
| Crystal structure of TIGIT in complexed with Ociperlimab, crystal form II | Descriptor: | T-cell immunoreceptor with Ig and ITIM domains, antibody heavy chain, antibody light chain | Authors: | Sun, J, Zhang, X.X, Song, J. | Deposit date: | 2023-05-16 | Release date: | 2024-02-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab. Structure, 32, 2024
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5GGS
| PD-1 in complex with pembrolizumab Fab | Descriptor: | Programmed cell death protein 1, heavy chain, light chain | Authors: | Heo, Y.S. | Deposit date: | 2016-06-16 | Release date: | 2016-11-09 | Last modified: | 2016-11-16 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGV
| CTLA-4 in complex with tremelimumab Fab | Descriptor: | Cytotoxic T-lymphocyte protein 4, heavy chain, light chain | Authors: | Heo, Y.S. | Deposit date: | 2016-06-16 | Release date: | 2016-11-09 | Last modified: | 2016-11-16 | Method: | X-RAY DIFFRACTION (1.998 Å) | Cite: | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGT
| PD-L1 in complex with BMS-936559 Fab | Descriptor: | IGK@ protein, IgG H chain, Programmed cell death 1 ligand 1 | Authors: | Heo, Y.S. | Deposit date: | 2016-06-16 | Release date: | 2016-11-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGR
| PD-1 in complex with nivolumab Fab | Descriptor: | Programmed cell death protein 1, heavy chain, light chain | Authors: | Heo, Y.S. | Deposit date: | 2016-06-16 | Release date: | 2016-11-09 | Last modified: | 2016-11-16 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5IMO
| Nanobody targeting mouse Vsig4 in Spacegroup P3221 | Descriptor: | Nanobody, Protein Vsig4 | Authors: | Wen, Y, Zheng, F. | Deposit date: | 2016-03-06 | Release date: | 2017-01-11 | Last modified: | 2017-07-05 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity Immunobiology, 222, 2017
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5HDO
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5IR3
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5IMM
| Nanobody targeting mouse Vsig4 in Spacegroup P212121 | Descriptor: | Nanobody, Protein Vsig4 | Authors: | Wen, Y, Zheng, F. | Deposit date: | 2016-03-06 | Release date: | 2017-01-11 | Last modified: | 2017-07-05 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity Immunobiology, 222, 2017
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1VFA
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1WZ1
| Crystal structure of the Fv fragment complexed with dansyl-lysine | Descriptor: | Ig heavy chain, Ig light chain, N~6~-{[5-(DIMETHYLAMINO)-1-NAPHTHYL]SULFONYL}-L-LYSINE | Authors: | Nakasako, M, Oka, T, Mashumo, M, Takahashi, H, Shimada, I, Yamaguchi, Y, Kato, K, Arata, Y. | Deposit date: | 2005-02-21 | Release date: | 2006-01-31 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Conformational dynamics of complementarity-determining region H3 of an anti-dansyl Fv fragment in the presence of its hapten J.Mol.Biol., 351, 2005
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1WTL
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1VES
| Structure of New Antigen Receptor variable domain from sharks | Descriptor: | New Antigen Receptor variable domain | Authors: | Streltsov, V.A. | Deposit date: | 2004-04-05 | Release date: | 2004-08-24 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Structural evidence for evolution of shark Ig new antigen receptor variable domain antibodies from a cell-surface receptor Proc.Natl.Acad.Sci.USA, 101, 2004
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1VER
| Structure of New Antigen Receptor variable domain from sharks | Descriptor: | New Antigen Receptor variable domain | Authors: | Streltsov, V.A. | Deposit date: | 2004-04-05 | Release date: | 2004-08-24 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.82 Å) | Cite: | Structural evidence for evolution of shark Ig new antigen receptor variable domain antibodies from a cell-surface receptor Proc.Natl.Acad.Sci.USA, 101, 2004
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1Z9M
| Crystal Structure of Nectin-like molecule-1 protein Domain 1 | Descriptor: | GAPA225 | Authors: | Dong, X, Xu, F, Gong, Y, Gao, J, Lin, P, Chen, T, Peng, Y, Qiang, B, Yuan, J, Peng, X, Rao, Z. | Deposit date: | 2005-04-03 | Release date: | 2006-02-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of the V Domain of Human Nectin-like Molecule-1/Syncam3/Tsll1/Igsf4b, a Neural Tissue-specific Immunoglobulin-like Cell-Cell Adhesion Molecule J.Biol.Chem., 281, 2006
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1XT5
| Crystal Structure of VCBP3, domain 1, from Branchiostoma floridae | Descriptor: | SULFATE ION, variable region-containing chitin-binding protein 3 | Authors: | Hernandez Prada, J.A, Haire, R.N, Cannon, J.P, Allaire, M, Jakoncic, J, Stojanoff, V, Litman, G.W, Ostrov, D.A. | Deposit date: | 2004-10-21 | Release date: | 2005-10-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Ancient evolutionary origin of diversified variable regions demonstrated by crystal structures of an immune-type receptor in amphioxus. Nat.Immunol., 7, 2006
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