5MC7
 
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2HF6
 | | Solution structure of human zeta-COP | | 分子名称: | Coatomer subunit zeta-1 | | 著者 | Yu, W, Jin, C, Xia, B. | | 登録日 | 2006-06-23 | | 公開日 | 2007-06-12 | | 最終更新日 | 2011-11-30 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of human zeta-COP: direct evidences for structural similarity between COP I and clathrin-adaptor coats
J.Mol.Biol., 386, 2009
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5MU7
 | | Crystal Structure of the beta/delta-COPI Core Complex | | 分子名称: | Coatomer subunit beta, Coatomer subunit delta-like protein | | 著者 | Kopp, J, Aderhold, P, Wieland, F, Sinning, I. | | 登録日 | 2017-01-12 | | 公開日 | 2017-06-28 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
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4UQI
 | | AP2 controls clathrin polymerization with a membrane-activated switch | | 分子名称: | AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA, AP-2 COMPLEX SUBUNIT MU, ... | | 著者 | Kelly, B.T, Graham, S.C, Liska, N, Dannhauser, P.N, Hoening, S, Ungewickell, E.J, Owen, D.J. | | 登録日 | 2014-06-23 | | 公開日 | 2014-07-30 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Clathrin Adaptors. Ap2 Controls Clathrin Polymerization with a Membrane-Activated Switch.
Science, 345, 2014
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8T1O
 | | AP2 bound to MSP2N2 nanodisc with Tgn38 cargo peptide; composite map | | 分子名称: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | | 著者 | Baker, R.W, Cannon, K.S, Reta, S. | | 登録日 | 2023-06-02 | | 公開日 | 2023-07-12 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Lipid nanodiscs as a template for high-resolution cryo-EM structures of peripheral membrane proteins.
J.Struct.Biol., 215, 2023
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6URI
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3TJZ
 | | Crystal Structure of Arf1 Bound to the gamma/zeta-COP Core Complex | | 分子名称: | ADP-ribosylation factor 1, Coatomer subunit gamma, Coatomer subunit zeta-1, ... | | 著者 | Goldberg, J, Yu, X, Breitman, M. | | 登録日 | 2011-08-25 | | 公開日 | 2012-02-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | A structure-based mechanism for arf1-dependent recruitment of coatomer to membranes.
Cell(Cambridge,Mass.), 148, 2012
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4HMY
 | | Structural basis for recruitment and activation of the AP-1 clathrin adaptor complex by Arf1 | | 分子名称: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | 著者 | Ren, X, Farias, G.G, Canagarajah, B.J, Bonifacino, J.S, Hurley, J.H. | | 登録日 | 2012-10-18 | | 公開日 | 2013-03-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (7 Å) | | 主引用文献 | Structural Basis for Recruitment and Activation of the AP-1 Clathrin Adaptor Complex by Arf1.
Cell(Cambridge,Mass.), 152, 2013
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7Z5C
 | | Chimera of AP2 with FCHO2 linker domain as a fusion on Cmu2 subunit | | 分子名称: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | | 著者 | Kane Dickson, V, Qu, K, Owen, D.J, Briggs, J.A, Zaccai, N.R. | | 登録日 | 2022-03-09 | | 公開日 | 2022-05-11 | | 実験手法 | ELECTRON MICROSCOPY (4.16 Å) | | 主引用文献 | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
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7UX3
 | | Asymmetric unit of AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes | | 分子名称: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | 著者 | Hooy, R.M, Hurley, J.H. | | 登録日 | 2022-05-04 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (9.6 Å) | | 主引用文献 | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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2BP5
 | | MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH NON-CANONICAL INTERNALIZATION PEPTIDE VEDYEQGLSG | | 分子名称: | CLATHRIN COAT ASSEMBLY PROTEIN AP50, P2X PURINOCEPTOR 4 | | 著者 | Royle, S.J, Evans, P.R, Owen, D.J, Murrell-Lagnado, R.D. | | 登録日 | 2005-04-18 | | 公開日 | 2005-07-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Non-Canonical Yxxg-Phi Endocytic Motifs: Recognition by Ap2 and Preferential Utilization in P2X4 Receptors.
J.Cell.Sci, 118, 2005
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1W63
 | | AP1 clathrin adaptor core | | 分子名称: | ADAPTER-RELATED PROTEIN COMPLEX 1 BETA 1 SUBUNIT, ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT, ADAPTER-RELATED PROTEIN COMPLEX 1 SIGMA 1A SUBUNIT, ... | | 著者 | Heldwein, E, Macia, E, Wang, J, Yin, H.L, Kirchhausen, T, Harrison, S.C. | | 登録日 | 2004-08-12 | | 公開日 | 2004-09-21 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Crystal Structure of the Clathrin Adaptor Protein 1 Core
Proc.Natl.Acad.Sci.USA, 101, 2004
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5FPI
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6QH6
 | | AP2 clathrin adaptor core with two cargo peptides in open+ conformation | | 分子名称: | AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | | 著者 | Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R. | | 登録日 | 2019-01-15 | | 公開日 | 2019-09-04 | | 最終更新日 | 2022-12-07 | | 実験手法 | X-RAY DIFFRACTION (5 Å) | | 主引用文献 | Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
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6QH7
 | | AP2 clathrin adaptor mu2T156-phosphorylated core with two cargo peptides in open+ conformation | | 分子名称: | ADAPTOR-RELATED PROTEIN COMPLEX 2, MU 2 SUBUNIT, C-TERMINAL DOMAIN, ... | | 著者 | Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R. | | 登録日 | 2019-01-15 | | 公開日 | 2019-09-04 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
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2VGL
 | | AP2 CLATHRIN ADAPTOR CORE | | 分子名称: | ADAPTOR PROTEIN COMPLEX AP-2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA-1, ... | | 著者 | Owen, D.J, Collins, B.M, McCoy, A.J, Evans, P.R. | | 登録日 | 2007-11-14 | | 公開日 | 2007-12-25 | | 最終更新日 | 2020-10-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Molecular Architecture and Functional Model of the Endocytic Ap2 Complex
Cell(Cambridge,Mass.), 109, 2002
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2XA7
 | | AP2 clathrin adaptor core in active complex with cargo peptides | | 分子名称: | ADAPTOR-RELATED PROTEIN COMPLEX 2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA, ... | | 著者 | Jackson, L.P, Kelly, B.T, McCoy, A.J, Evans, P.R, Owen, D.J. | | 登録日 | 2010-03-29 | | 公開日 | 2010-07-21 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | A Large Scale Conformational Change Couples Membrane Recruitment to Cargo Binding in the Ap2 Clathrin Adaptor Complex
Cell(Cambridge,Mass.), 141, 2010
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4NEE
 | | crystal structure of AP-2 alpha/simga2 complex bound to HIV-1 Nef | | 分子名称: | AP-2 complex subunit alpha-2, AP-2 complex subunit sigma, Protein Nef | | 著者 | Hurley, J.H, Bonifacino, J.S, Ren, X, Park, S.Y. | | 登録日 | 2013-10-29 | | 公開日 | 2014-01-29 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.8841 Å) | | 主引用文献 | How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4.
Elife, 3, 2014
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4P6Z
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6CM9
 | | Structure of the cargo bound AP-1:Arf1:tetherin-Nef closed trimer monomeric subunit | | 分子名称: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | 著者 | Morris, K.L, Buffalo, C.Z, Ren, X, Hurley, J.H. | | 登録日 | 2018-03-03 | | 公開日 | 2018-08-08 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | | 主引用文献 | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
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6CRI
 | | Structure of the cargo bound AP-1:Arf1:tetherin-Nef stable closed trimer | | 分子名称: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | 著者 | Morris, K.L, Buffalo, C.Z, Hurley, J.H. | | 登録日 | 2018-03-18 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | | 主引用文献 | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
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6D84
 | | Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer | | 分子名称: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | 著者 | Buffalo, C.Z, Morris, K.L, Hurley, J.H. | | 登録日 | 2018-04-25 | | 公開日 | 2018-08-08 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (6.72 Å) | | 主引用文献 | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
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6YAF
 | | AP2 on a membrane containing tyrosine-based cargo peptide | | 分子名称: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | | 著者 | Kovtun, O, Kane Dickson, V, Kelly, B.T, Owen, D, Briggs, J.A.G. | | 登録日 | 2020-03-12 | | 公開日 | 2020-07-29 | | 最終更新日 | 2020-08-19 | | 実験手法 | ELECTRON MICROSCOPY (9.1 Å) | | 主引用文献 | Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles.
Sci Adv, 6, 2020
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6DFF
 | | Structure of the cargo bound AP-1:Arf1:tetherin-Nef monomer | | 分子名称: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | 著者 | Morris, K.L, Buffalo, C.Z, Ren, X, Hurley, J.H. | | 登録日 | 2018-05-14 | | 公開日 | 2018-08-08 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
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6D83
 | | Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer monomeric subunit | | 分子名称: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | 著者 | Buffalo, C.Z, Morris, K.L, Hurley, J.H. | | 登録日 | 2018-04-25 | | 公開日 | 2018-08-08 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.27 Å) | | 主引用文献 | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
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