PDB: 149 resultsInfo pagesStatus searchChemie searchBIRD

---

5UMK	Crystal structure of H62Y mutant of human macrophage migration inhibitory factor Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... Authors: Pantouris, G, Lolis, E. Deposit date: 2017-01-27 Release date: 2018-02-07 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel. Cell Chem Biol, 27, 2020
5UMJ	Crystal structure of H62A mutant of human macrophage migration inhibitory factor Descriptor: ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, SULFATE ION Authors: Pantouris, G, Lolis, E. Deposit date: 2017-01-27 Release date: 2018-02-07 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel. Cell Chem Biol, 27, 2020
5UZY	Crystal structure of N97A mutant of human macrophage migration inhibitory factor Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... Authors: Pantouris, G, Lolis, E. Deposit date: 2017-02-27 Release date: 2018-02-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74. Angew. Chem. Int. Ed. Engl., 57, 2018
5V70	Crystal structure of N102A mutant of human macrophage migration inhibitory factor Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... Authors: Pantouris, G, Lolis, E. Deposit date: 2017-03-17 Release date: 2018-03-21 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.94 Å) Cite: Crystal structure of N102A mutant of human macrophage migration inhibitory factor To Be Published
5V73	Crystal structure of N110A mutant of human macrophage migration inhibitory factor Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... Authors: Pantouris, G, Lolis, E. Deposit date: 2017-03-17 Release date: 2018-03-21 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Crystal structure of N110A mutant of human macrophage migration inhibitory factor To Be Published
6CBG	Macrophage Migration Inhibitory Factor in Complex with a Pyrazole Inhibitor (5) Descriptor: 3-(1H-pyrazol-4-yl)benzoic acid, GLYCEROL, Macrophage migration inhibitory factor, ... Authors: Robertson, M.J, Krimmer, S.G, Jorgensen, W.L. Deposit date: 2018-02-02 Release date: 2018-04-04 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2 Å) Cite: Optimization of Pyrazoles as Phenol Surrogates to Yield Potent Inhibitors of Macrophage Migration Inhibitory Factor. ChemMedChem, 13, 2018
6CBH	Macrophage Migration Inhibitory Factor in Complex with a Pyrazole Inhibitor (8m) Descriptor: 5-(3-fluoro-1H-pyrazol-4-yl)-2-[(naphthalen-2-yl)oxy]benzoic acid, GLYCEROL, ISOPROPYL ALCOHOL, ... Authors: Robertson, M.J, Krimmer, S.G, Jorgensen, W.L. Deposit date: 2018-02-02 Release date: 2018-04-04 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Optimization of Pyrazoles as Phenol Surrogates to Yield Potent Inhibitors of Macrophage Migration Inhibitory Factor. ChemMedChem, 13, 2018
6CBF	Macrophage Migration Inhibitory Factor in Complex with a Pyrazole Inhibitor (6a) Descriptor: 2-phenoxy-5-(1H-pyrazol-4-yl)benzoic acid, Macrophage migration inhibitory factor, SULFATE ION Authors: Robertson, M.J, Krimmer, S.G, Jorgensen, W.L. Deposit date: 2018-02-02 Release date: 2018-04-04 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Optimization of Pyrazoles as Phenol Surrogates to Yield Potent Inhibitors of Macrophage Migration Inhibitory Factor. ChemMedChem, 13, 2018
6CB5	Macrophage Migration Inhibitory Factor in complex with a Pyrazole Inhibitor (8g) Descriptor: 2-[(naphthalen-2-yl)oxy]-5-(1H-pyrazol-4-yl)benzoic acid, Macrophage migration inhibitory factor, SULFATE ION Authors: Krimmer, S.G, Robertson, M.J, Jorgensen, W.L. Deposit date: 2018-02-02 Release date: 2018-04-04 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Optimization of Pyrazoles as Phenol Surrogates to Yield Potent Inhibitors of Macrophage Migration Inhibitory Factor. ChemMedChem, 13, 2018
6CUQ	Crystal structure of Macrophage migration inhibitory factor-like protein (EhMIF) from Entamoeba histolytica Descriptor: 1,2-ETHANEDIOL, Macrophage migration inhibitory factor-like protein Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-03-26 Release date: 2018-04-11 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Crystal structure of Macrophage migration inhibitory factor-like protein (EhMIF) from Entamoeba histolytica to be published
6FVE	Macrophage Migration Inhibitory Factor (MIF) with Covalently Bound FITC Descriptor: 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-5-[(E)-(sulfanylmethylidene)amino]benzoic acid, Macrophage migration inhibitory factor, SULFATE ION Authors: Samygina, V.R, Bourenkov, G, Sokolov, A.V. Deposit date: 2018-03-02 Release date: 2018-06-06 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.41 Å) Cite: Structural Study of the Complex Formed by Ceruloplasmin and Macrophage Migration Inhibitory Factor. Biochemistry Mosc., 83, 2018
6FVH	Macrophage Migration Inhibitory Factor (MIF) with Covalently Bound PITC Descriptor: Macrophage migration inhibitory factor, N-phenylthioformamide, SULFATE ION Authors: Samygina, V.R, Bourenkov, G, Sokolov, A.V. Deposit date: 2018-03-02 Release date: 2018-06-06 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structural Study of the Complex Formed by Ceruloplasmin and Macrophage Migration Inhibitory Factor. Biochemistry Mosc., 83, 2018
6BG7	Crystal structure of G107A mutant of human macrophage migration inhibitory factor Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... Authors: Pantouris, G, Lolis, E. Deposit date: 2017-10-27 Release date: 2018-06-06 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.54 Å) Cite: Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74. Angew. Chem. Int. Ed. Engl., 57, 2018
6BG6	Crystal structure of S111A mutant of human macrophage migration inhibitory factor Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... Authors: Pantouris, G, Lolis, E. Deposit date: 2017-10-27 Release date: 2018-06-06 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.52 Å) Cite: Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74. Angew. Chem. Int. Ed. Engl., 57, 2018
6C5F	Human D-Dopachrome tautomerase (D-DT)/ macrophage migration inhibitory factor 2 (MIF2) complexed with the selective inhibitor 4-CPPC Descriptor: 4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid, D-dopachrome decarboxylase Authors: Pantouris, G, Lolis, E.J. Deposit date: 2018-01-16 Release date: 2018-06-13 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structural Plasticity in the C-Terminal Region of Macrophage Migration Inhibitory Factor-2 Is Associated with an Induced Fit Mechanism for a Selective Inhibitor. Biochemistry, 57, 2018
5XEJ	Crystal Structure of Macrophage Migration Inhibitory Factor bound to MTX Descriptor: (2~{R})-2-[[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-methyl-amino]phenyl]carbonylamino]pentanedioic acid, Macrophage migration inhibitory factor, SULFATE ION Authors: Takimoto-Kamimura, M, Fukushima, K. Deposit date: 2017-04-05 Release date: 2018-07-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of macrophage migration inhibitory factor in complex with methotrexate. Acta Crystallogr D Struct Biol, 77, 2021
6ICE	Crystal structure of Hamster MIF Descriptor: Macrophage migration inhibitory factor Authors: Sundaram, R, Vasudevan, D. Deposit date: 2018-09-05 Release date: 2019-09-11 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Macrophage migration inhibitory factor of Syrian golden hamster shares structural and functional similarity with human counterpart and promotes pancreatic cancer. Sci Rep, 9, 2019
6PEG	MIF with a allosteric inhibitor Descriptor: 4-amino-5-hydroxy-6-[(E)-(3-{[3-(2-methylpropanoyl)pyrazolo[1,5-a]pyridin-2-yl]methyl}phenyl)diazenyl]naphthalene-1,3-disulfonic acid, ACETATE ION, GLYCEROL, ... Authors: Asojo, O.A. Deposit date: 2019-06-20 Release date: 2019-11-27 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2 Å) Cite: Inhibition of Macrophage Migration Inhibitory Factor by a Chimera of Two Allosteric Binders. Acs Med.Chem.Lett., 11, 2020
6OYB	Crystal structure of H62G mutant of human macrophage migration inhibitory factor Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... Authors: Pantouris, G, Lolis, E. Deposit date: 2019-05-14 Release date: 2020-04-22 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel. Cell Chem Biol, 27, 2020
6OY8	Crystal structure of Y99G mutant of human macrophage migration inhibitory factor Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... Authors: Pantouris, G, Lolis, E. Deposit date: 2019-05-14 Release date: 2020-04-22 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel. Cell Chem Biol, 27, 2020
6OYG	Crystal structure of H62F mutant of human macrophage migration inhibitory factor Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... Authors: Pantouris, G, Lolis, E. Deposit date: 2019-05-14 Release date: 2020-04-22 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel. Cell Chem Biol, 27, 2020
6OYE	Crystal structure of Y99F mutant of human macrophage migration inhibitory factor Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... Authors: Pantouris, G, Lolis, E. Deposit date: 2019-05-14 Release date: 2020-04-29 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel. Cell Chem Biol, 27, 2020
6LR3	Structural and functional insights into macrophage migration inhibitory factor from Oncomelania hupensis, the intermediate host of Schistosoma japonicum Descriptor: Macrophage migration inhibitory factor, SULFATE ION Authors: Su, Z.M, Tian, X.Y, Li, H.J, Wei, Z.M, Chen, L.F, Ren, H.X, Peng, W.F, Tang, C.T. Deposit date: 2020-01-15 Release date: 2020-07-22 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Structural and functional insights into macrophage migration inhibitory factor from Oncomelania hupensis, the intermediate host of Schistosoma japonicum. Biochem.J., 477, 2020
6LKV	Structural and functional insights into macrophage migration inhibitory factor from Oncomelania hupensis, the intermediate host of Schistosoma japonicum Descriptor: CHLORIDE ION, Macrophage migration inhibitory factor, SULFATE ION Authors: Su, Z.M, Tian, X.Y, Li, H.J, Wei, Z.M, Chen, L.F, Ren, H.X, Peng, W.F, Tang, C.T. Deposit date: 2019-12-20 Release date: 2020-07-22 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural and functional insights into macrophage migration inhibitory factor from Oncomelania hupensis, the intermediate host of Schistosoma japonicum. Biochem.J., 477, 2020
6LKW	Structural and functional insights into macrophage migration inhibitory factor from Oncomelania hupensis, the intermediate host of Schistosoma japonicum Descriptor: CHLORIDE ION, Macrophage migration inhibitory factor Authors: Su, Z.M, Tian, X.Y, Li, H.J, Wei, Z.M, Chen, L.F, Ren, H.X, Peng, W.F, Tang, C.T. Deposit date: 2019-12-20 Release date: 2020-07-22 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural and functional insights into macrophage migration inhibitory factor from Oncomelania hupensis, the intermediate host of Schistosoma japonicum. Biochem.J., 477, 2020

<123456>