PDB: 65 件ウェブページステータス検索Chemie searchBIRD

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7UTJ	Cryogenic electron microscopy 3D map of F-actin bound by human dimeric alpha-catenin 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Rangarajan, E.S, Smith, E.W, Izard, T. 登録日 2022-04-27 公開日 2023-03-08 最終更新日 2023-03-29 実験手法 ELECTRON MICROSCOPY (2.77 Å) 主引用文献 Distinct inter-domain interactions of dimeric versus monomeric alpha-catenin link cell junctions to filaments. Commun Biol, 6, 2023
7KTU	Cryogenic electron microscopy model of full-length human metavinculin H1'-parallel conformation 1 分子名称: metavinculin 著者 Izard, T, Rangarajan, E.S. 登録日 2020-11-24 公開日 2021-01-27 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.15 Å) 主引用文献 The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain. Int J Mol Sci, 22, 2021
7KTV	Cryogenic electron microscopy model of full-length human metavinculin H1' kinked conformation 分子名称: metavinculin 著者 Izard, T, Rangarajan, E.S. 登録日 2020-11-24 公開日 2021-01-27 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain. Int J Mol Sci, 22, 2021
7KTT	Cryogenic electron microscopy model of full-length human metavinculin 分子名称: metavinculin 著者 Izard, T, Rangarajan, E.S. 登録日 2020-11-24 公開日 2021-01-27 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.17 Å) 主引用文献 The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain. Int J Mol Sci, 22, 2021
7KTW	Cryogenic electron microscopy model of full-length human metavinculin H1'-parallel conformation 2 分子名称: metavinculin 著者 Izard, T, Rangarajan, E.S. 登録日 2020-11-24 公開日 2021-01-27 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.27 Å) 主引用文献 The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain. Int J Mol Sci, 22, 2021
6UPV	Alpha-E-catenin ABD-F-actin complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Mei, L, Alushin, G.M. 登録日 2019-10-18 公開日 2020-09-30 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Molecular mechanism for direct actin force-sensing by alpha-catenin. Elife, 9, 2020
6UPW	Metavinculin ABD-F-actin complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Mei, L, Alushin, G.M. 登録日 2019-10-18 公開日 2020-09-30 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Molecular mechanism for direct actin force-sensing by alpha-catenin. Elife, 9, 2020
6O3E	mouse aE-catenin 82-883 分子名称: Catenin alpha-1 著者 Pokutta, S, Weis, W.I. 登録日 2019-02-26 公開日 2019-11-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.001 Å) 主引用文献 Binding partner- and force-promoted changes in alpha E-catenin conformation probed by native cysteine labeling. Sci Rep, 9, 2019
6NR7	Rerefinement of chicken vinculin 分子名称: (1R,2R,3S,4R,5R,6S)-4-{[(S)-[(2S)-2,3-dihydroxypropoxy](hydroxy)phosphoryl]oxy}-3,5,6-trihydroxycyclohexane-1,2-diyl bis[dihydrogen (phosphate)], PHOSPHATE ION, SULFATE ION, ... 著者 Stec, B. 登録日 2019-01-23 公開日 2020-01-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Refined model of chicken vinculin suggests the mechanism of activation by helical super-bundle unfurling To be published
6DUW	Crystal structure of the alpha-N-catenin actin-binding domain H1 mutant 分子名称: Catenin alpha-2 著者 Ishiyama, N, Ikura, M. 登録日 2018-06-22 公開日 2018-12-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Force-dependent allostery of the alpha-catenin actin-binding domain controls adherens junction dynamics and functions. Nat Commun, 9, 2018
6DUY	Crystal structure of the alpha-N-catenin actin-binding domain H1 mutant 分子名称: Catenin alpha-2 著者 Ishiyama, N, Ikura, M. 登録日 2018-06-22 公開日 2018-12-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Force-dependent allostery of the alpha-catenin actin-binding domain controls adherens junction dynamics and functions. Nat Commun, 9, 2018
6FUY	Crystal structure of human full-length vinculin-T12-A974K (residues 1-1066) 分子名称: CALCIUM ION, Vinculin 著者 Chorev, D.S, Volberg, T, Livne, A, Eisenstein, M, Martins, B, Kam, Z, Jockusch, B.M, Medalia, O, Sharon, M, Geiger, B. 登録日 2018-02-28 公開日 2018-03-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Conformational states during vinculin unlocking differentially regulate focal adhesion properties. Sci Rep, 8, 2018
6FQ4	Structure of Chlamydial virulence factor TarP and vinculin head domain 分子名称: TarP-VBS1, Vinculin 著者 Whitewood, A.J, Singh, A.K, Brown, D.G, Goult, B.T. 登録日 2018-02-13 公開日 2018-05-09 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Chlamydial virulence factor TarP mimics talin to disrupt the talin-vinculin complex. FEBS Lett., 592, 2018
6BFI	Vinculin homolog in a sponge (phylum Porifera) reveals vertebrate-like cell adhesions involved in early multicellular evolution 分子名称: VIN1 著者 Weis, W.I, Chodaparambil, J.V. 登録日 2017-10-26 公開日 2018-06-13 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Analysis of a vinculin homolog in a sponge (phylum Porifera) reveals that vertebrate-like cell adhesions emerged early in animal evolution. J. Biol. Chem., 293, 2018
5Y04	Crystal Structure of the complex between the vinculin D1 domain and alphaE-catenin 分子名称: Catenin alpha-1, Vinculin 著者 Hirano, Y, Hakoshima, T. 登録日 2017-07-14 公開日 2018-03-28 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 The force-sensing device region of alpha-catenin is an intrinsically disordered segment in the absence of intramolecular stabilization of the autoinhibitory form Genes Cells, 23, 2018
5XFL	Crystal structure of the force-sensing device region of alpha N-catenin 分子名称: Catenin alpha-2 著者 Hirano, Y, Hakoshima, T. 登録日 2017-04-10 公開日 2018-03-28 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 The force-sensing device region of alpha-catenin is an intrinsically disordered segment in the absence of intramolecular stabilization of the autoinhibitory form Genes Cells, 23, 2018
5XA5	Crystal structure of HMP-1-HMP-2 complex 分子名称: Alpha-catenin-like protein hmp-1, Beta-catenin-like protein hmp-2 著者 Shao, X, Kang, H, Weis, W.I, Hardin, J, Choi, H.J. 登録日 2017-03-11 公開日 2017-08-30 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Cell-cell adhesion in metazoans relies on evolutionarily conserved features of the alpha-catenin· beta-catenin-binding interface. J.Biol.Chem., 292, 2017
5H5M	Crystal structure of HMP-1 M domain 分子名称: Alpha-catenin-like protein hmp-1 著者 Kang, H, Bang, I, Weis, W.I, Choi, H.J. 登録日 2016-11-08 公開日 2017-03-29 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural and functional characterization of Caenorhabditis elegans alpha-catenin reveals constitutive binding to beta-catenin and F-actin J. Biol. Chem., 292, 2017
5L0F	Human metavinculin quadruple mutant (residues 959-1134) 分子名称: GLYCEROL, Vinculin 著者 Chinthalapudi, K, Izard, T. 登録日 2016-07-27 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization. Proc.Natl.Acad.Sci.USA, 113, 2016
5L0G	Human metavinculin MVt Q971R, R975D, T978R mutant (residues 959-1134) in complex with PIP2 分子名称: Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate 著者 Chinthalapudi, K, Izard, T. 登録日 2016-07-27 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization. Proc.Natl.Acad.Sci.USA, 113, 2016
5L0D	Human Metavinculin(residues 959-1130) in complex with PIP2 分子名称: Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate 著者 Chinthalapudi, K, Izard, T. 登録日 2016-07-27 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization. Proc.Natl.Acad.Sci.USA, 113, 2016
5L0H	Human metavinculin MVt cardiomyopathy-associated mutant R975W (residues 959-1134) in complex with PIP2 分子名称: DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, Vinculin, ... 著者 Chinthalapudi, K, Izard, T. 登録日 2016-07-27 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization. Proc.Natl.Acad.Sci.USA, 113, 2016
5L0I	Human metavinculin MVt R975W cardiomyopathy-associated mutant (residues 959-1134) 分子名称: GLYCEROL, SODIUM ION, Vinculin 著者 Chinthalapudi, K, Izard, T. 登録日 2016-07-27 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization. Proc.Natl.Acad.Sci.USA, 113, 2016
5L0C	Human metavinculin (residues 959-1134) in complex with PIP2 分子名称: PHOSPHATE ION, Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate 著者 Chinthalapudi, K, Izard, T. 登録日 2016-07-27 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization. Proc.Natl.Acad.Sci.USA, 113, 2016
5L0J	Human vinculin R903Q, D907R, R910T mutant(residues 891-1066) 分子名称: Vinculin 著者 Chinthalapudi, K, Izard, T. 登録日 2016-07-27 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization. Proc.Natl.Acad.Sci.USA, 113, 2016

 

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