PDB: 338 件ウェブページステータス検索Chemie searchBIRD

---

6PWW	Cryo-EM structure of MLL1 in complex with RbBP5 and WDR5 bound to the nucleosome 分子名称: DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... 著者 Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U. 登録日 2019-07-23 公開日 2019-12-18 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Cryo-EM structure of the human MLL1 core complex bound to the nucleosome. Nat Commun, 10, 2019
7AT8	Histone H3 recognition by nucleosome-bound PRC2 subunit EZH2. 分子名称: Histone H2A, Histone H2B 1.1, Histone H3.2, ... 著者 Finogenova, K, Benda, C, Schaefer, I.B, Poepsel, S, Strauss, M, Mueller, J. 登録日 2020-10-29 公開日 2020-12-09 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structural basis for PRC2 decoding of active histone methylation marks H3K36me2/3. Elife, 9, 2020
6KIZ	Cryo-EM structure of human MLL1-NCP complex, binding mode2 分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ... 著者 Huang, J, Xue, H, Yao, T. 登録日 2019-07-20 公開日 2019-09-11 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
5HQ2	Structural model of Set8 histone H4 Lys20 methyltransferase bound to nucleosome core particle 分子名称: DNA (149-MER), Guanine nucleotide exchange factor SRM1, Histone H2A, ... 著者 Tavarekere, G, McGinty, R.K, Tan, S. 登録日 2016-01-21 公開日 2016-03-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (4.5 Å) 主引用文献 Multivalent Interactions by the Set8 Histone Methyltransferase With Its Nucleosome Substrate. J.Mol.Biol., 428, 2016
6W5M	Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class02) 分子名称: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... 著者 Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U. 登録日 2020-03-13 公開日 2021-03-31 最終更新日 2022-10-12 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin. Nat Commun, 12, 2021
7KTP	PRC2:EZH1_B from a dimeric PRC2 bound to a nucleosome 分子名称: Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH1, Polycomb protein EED, ... 著者 Grau, D.J, Armache, K.J. 登録日 2020-11-24 公開日 2021-02-03 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction. Nat Commun, 12, 2021
6W5N	Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class05) 分子名称: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... 著者 Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U. 登録日 2020-03-13 公開日 2021-03-31 最終更新日 2022-10-12 実験手法 ELECTRON MICROSCOPY (6 Å) 主引用文献 Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin. Nat Commun, 12, 2021
6PWV	Cryo-EM structure of MLL1 core complex bound to the nucleosome 分子名称: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... 著者 Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U. 登録日 2019-07-23 公開日 2019-12-18 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (6.2 Å) 主引用文献 Cryo-EM structure of the human MLL1 core complex bound to the nucleosome. Nat Commun, 10, 2019
6W5I	Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class01) 分子名称: DNA (147-MER), Histone H2A, Histone H2B 1.1, ... 著者 Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U. 登録日 2020-03-13 公開日 2021-03-31 最終更新日 2022-10-12 実験手法 ELECTRON MICROSCOPY (6.9 Å) 主引用文献 Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin. Nat Commun, 12, 2021
7MBM	Cryo-EM structure of MLL1-NCP (H3K4M) complex, mode01 分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ... 著者 Park, S.H, Ayoub, A, Lee, Y.T, Dou, Y, Cho, U. 登録日 2021-04-01 公開日 2021-12-29 最終更新日 2022-01-19 実験手法 ELECTRON MICROSCOPY 主引用文献 Regulation of MLL1 Methyltransferase Activity in Two Distinct Nucleosome Binding Modes. Biochemistry, 61, 2022
7MBN	Cryo-EM structure of MLL1-NCP (H3K4M) complex, mode02 分子名称: DNA (146-MER), Histone H2A, Histone H2B 1.1, ... 著者 Park, S.H, Ayoub, A, Lee, Y.T, Dou, Y, Cho, U. 登録日 2021-04-01 公開日 2021-12-29 最終更新日 2022-01-19 実験手法 ELECTRON MICROSCOPY 主引用文献 Regulation of MLL1 Methyltransferase Activity in Two Distinct Nucleosome Binding Modes. Biochemistry, 61, 2022
1N3J	Structure and Substrate of a Histone H3 Lysine Methyltransferase from Paramecium Bursaria Chlorella Virus 1 分子名称: Histone H3 Lysine Methyltransferase 著者 Manzur, K.L, Farooq, A, Zeng, L, Plotnikova, O, Sachchidanand, Koch, A.W, Zhou, M.-M. 登録日 2002-10-28 公開日 2003-01-28 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 A dimeric viral SET domain methyltransferase specific to Lys27 of histone H3. Nat.Struct.Biol., 10, 2003
2G46	structure of vSET in complex with meK27 H3 Pept. and cofactor product SAH 分子名称: PBCV-1 histone H3-Lys 27 methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, meK27 H3 Peptide 著者 Qian, C.M, Zheng, L, Zhou, M.M. 登録日 2006-02-21 公開日 2006-12-05 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Structural insights of the specificity and catalysis of a viral histone H3 lysine 27 methyltransferase. J.Mol.Biol., 359, 2006

<7891011121314