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7MBM

Cryo-EM structure of MLL1-NCP (H3K4M) complex, mode01

Summary for 7MBM
Entry DOI10.2210/pdb7mbm/pdb
EMDB information23738
DescriptorRetinoblastoma-binding protein 5, DNA (145-MER), WD repeat-containing protein 5, ... (10 entities in total)
Functional Keywordsmll1-ncp, h3k4 methylation, transferase, transferase-dna binding protein-dna complex, transferase/dna binding protein/dna
Biological sourceHomo sapiens (Human)
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Total number of polymer chains14
Total formula weight377637.05
Authors
Park, S.H.,Ayoub, A.,Lee, Y.T.,Dou, Y.,Cho, U. (deposition date: 2021-04-01, release date: 2021-12-29, Last modification date: 2022-01-19)
Primary citationAyoub, A.,Park, S.H.,Lee, Y.T.,Cho, U.S.,Dou, Y.
Regulation of MLL1 Methyltransferase Activity in Two Distinct Nucleosome Binding Modes.
Biochemistry, 61:1-9, 2022
Cited by
PubMed: 34928138
DOI: 10.1021/acs.biochem.1c00603
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY
Structure validation

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