8BPA
| Cryo-EM structure of the human SIN3B histone deacetylase complex at 3.7 Angstrom | 分子名称: | CALCIUM ION, Histone deacetylase 2, Isoform 2 of Paired amphipathic helix protein Sin3b, ... | 著者 | Wan, M.S.M, Muhammad, R, Koliopolous, M.G, Alfieri, C. | 登録日 | 2022-11-16 | 公開日 | 2023-05-10 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex. Nat Commun, 14, 2023
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8BPB
| Cryo-EM structure of the human SIN3B histone deacetylase core complex at 2.8 Angstrom | 分子名称: | ACETATE ION, CALCIUM ION, Histone deacetylase 2, ... | 著者 | Wan, M.S.M, Muhammad, R, Koliopolous, M.G, Alfieri, C. | 登録日 | 2022-11-16 | 公開日 | 2023-05-10 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex. Nat Commun, 14, 2023
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8BPC
| Cryo-EM structure of the human SIN3B histone deacetylase core complex with SAHA at 2.8 Angstrom | 分子名称: | CALCIUM ION, Histone deacetylase 2, Isoform 2 of Paired amphipathic helix protein Sin3b, ... | 著者 | Wan, M.S.M, Muhammad, R, Koliopolous, M.G, Alfieri, C. | 登録日 | 2022-11-16 | 公開日 | 2023-05-10 | 最終更新日 | 2023-05-17 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex. Nat Commun, 14, 2023
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8C60
| Cryo-EM structure of the human SIN3B full-length complex at 3.4 Angstrom resolution | 分子名称: | CALCIUM ION, Histone deacetylase 2, Isoform 2 of Paired amphipathic helix protein Sin3b, ... | 著者 | Alfieri, C, Wan, S.M, Muhammad, R. | 登録日 | 2023-01-10 | 公開日 | 2023-05-10 | 最終更新日 | 2023-05-17 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex. Nat Commun, 14, 2023
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8CJ7
| HDAC6 selective degraded (difluoromethyl)-1,3,4-oxadiazole substrate inhibitor | 分子名称: | 6-[(5-pyridin-2-yl-1,2$l^{4},3,4-tetrazacyclopenta-1,3-dien-2-yl)methyl]pyridine-3-carbohydrazide, Histone deacetylase 6, IODIDE ION, ... | 著者 | Sandmark, J, Ek, M, Ripa, L. | 登録日 | 2023-02-12 | 公開日 | 2023-10-18 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Selective and Bioavailable HDAC6 2-(Difluoromethyl)-1,3,4-oxadiazole Substrate Inhibitors and Modeling of Their Bioactivation Mechanism. J.Med.Chem., 66, 2023
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8D98
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8D99
| Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with fluorinated inhibitor 7 | 分子名称: | 2,3,6-trifluoro-N-hydroxybenzamide, Hdac6 protein, POTASSIUM ION, ... | 著者 | Watson, P.R, Christianson, D.W. | 登録日 | 2022-06-09 | 公開日 | 2022-09-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Aromatic Ring Fluorination Patterns Modulate Inhibitory Potency of Fluorophenylhydroxamates Complexed with Histone Deacetylase 6. Biochemistry, 61, 2022
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8D9A
| Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with fluorinated inhibitor 8 | 分子名称: | 2,3,5-trifluoro-N-hydroxybenzamide, Hdac6 protein, POTASSIUM ION, ... | 著者 | Watson, P.R, Christianson, D.W. | 登録日 | 2022-06-09 | 公開日 | 2022-09-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Aromatic Ring Fluorination Patterns Modulate Inhibitory Potency of Fluorophenylhydroxamates Complexed with Histone Deacetylase 6. Biochemistry, 61, 2022
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8D9B
| Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with fluorinated inhibitor 9 | 分子名称: | 2,3,5,6-tetrafluoro-N-hydroxybenzamide, Hdac6 protein, POTASSIUM ION, ... | 著者 | Watson, P.R, Christianson, D.W. | 登録日 | 2022-06-09 | 公開日 | 2022-09-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Aromatic Ring Fluorination Patterns Modulate Inhibitory Potency of Fluorophenylhydroxamates Complexed with Histone Deacetylase 6. Biochemistry, 61, 2022
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8D9C
| Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with fluorinated inhibitor 10 | 分子名称: | 2,3,4,5,6-pentafluoro-N-hydroxybenzamide, Hdac6 protein, POTASSIUM ION, ... | 著者 | Watson, P.R, Christianson, D.W. | 登録日 | 2022-06-09 | 公開日 | 2022-09-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Aromatic Ring Fluorination Patterns Modulate Inhibitory Potency of Fluorophenylhydroxamates Complexed with Histone Deacetylase 6. Biochemistry, 61, 2022
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8EQI
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8G1Z
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8G20
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8GA8
| Structure of the yeast (HDAC) Rpd3L complex | 分子名称: | Histone deacetylase RPD3, Transcriptional regulatory protein DEP1, Transcriptional regulatory protein PHO23, ... | 著者 | Patel, A.B, Radhakrishnan, I, He, Y. | 登録日 | 2023-02-22 | 公開日 | 2023-07-12 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structure of the Saccharomyces cerevisiae Rpd3L histone deacetylase complex. Nat Commun, 14, 2023
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8GD4
| Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with DMFO Inhibitor 6 | 分子名称: | 2-(benzylamino)-N'-(difluoroacetyl)pyrimidine-5-carbohydrazide, Hdac6 protein, POTASSIUM ION, ... | 著者 | Watson, P.R, Craigin, A.D, Christianson, D.W. | 登録日 | 2023-03-03 | 公開日 | 2023-10-04 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Difluoromethyl-1,3,4-oxadiazoles Are Selective, Mechanism-Based, and Essentially Irreversible Inhibitors of Histone Deacetylase 6 . J.Med.Chem., 66, 2023
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8HPO
| Cryo-EM structure of a SIN3/HDAC complex from budding yeast | 分子名称: | Histone deacetylase RPD3, PHOSPHOTHREONINE, POTASSIUM ION, ... | 著者 | Guo, Z, Zhan, X, Wang, C. | 登録日 | 2022-12-12 | 公開日 | 2023-05-03 | 最終更新日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structure of a SIN3-HDAC complex from budding yeast. Nat.Struct.Mol.Biol., 30, 2023
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8HXX
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8HXY
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8HY0
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8I02
| Cryo-EM structure of the SIN3S complex from S. pombe | 分子名称: | Chromatin modification-related protein eaf3, Cph1, Histone deacetylase clr6, ... | 著者 | Wang, C, Guo, Z, Zhan, X. | 登録日 | 2023-01-10 | 公開日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Two assembly modes for SIN3 histone deacetylase complexes. Cell Discov, 9, 2023
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8I03
| Cryo-EM structure of the SIN3L complex from S. pombe | 分子名称: | Chromatin modification-related protein png2, Histone deacetylase clr6, POTASSIUM ION, ... | 著者 | Wang, C, Guo, Z, Zhan, X. | 登録日 | 2023-01-10 | 公開日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Two assembly modes for SIN3 histone deacetylase complexes. Cell Discov, 9, 2023
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8IFG
| Cryo-EM structure of the Clr6S (Clr6-HDAC) complex from S. pombe | 分子名称: | Chromatin modification-related protein eaf3, Cph1, Cph2, ... | 著者 | Zhang, H.Q, Wang, X, Wang, Y.N, Liu, S.M, Zhang, Y, Xu, K, Ji, L.T, Kornberg, R.D. | 登録日 | 2023-02-17 | 公開日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Class I histone deacetylase complex: Structure and functional correlates. Proc Natl Acad Sci U S A, 120, 2023
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8IHN
| Cryo-EM structure of the Rpd3S core complex | 分子名称: | CALCIUM ION, Chromatin modification-related protein EAF3, Histone H3, ... | 著者 | Zhang, Y, Gang, C. | 登録日 | 2023-02-23 | 公開日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | 主引用文献 | Structural basis for nucleosome binding and catalysis by the yeast Rpd3S/HDAC holoenzyme. Cell Res., 33, 2023
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8IHT
| Rpd3S bound to the nucleosome | 分子名称: | CALCIUM ION, Chromatin modification-related protein EAF3, DNA (164-MER), ... | 著者 | Zhang, Y, Gang, C. | 登録日 | 2023-02-23 | 公開日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | 主引用文献 | Structural basis for nucleosome binding and catalysis by the yeast Rpd3S/HDAC holoenzyme. Cell Res., 33, 2023
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8JHO
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