8BPC
Cryo-EM structure of the human SIN3B histone deacetylase core complex with SAHA at 2.8 Angstrom
Summary for 8BPC
| Entry DOI | 10.2210/pdb8bpc/pdb |
| EMDB information | 16147 16148 16149 |
| Descriptor | Isoform 2 of Paired amphipathic helix protein Sin3b, Histone deacetylase 2, PHD finger protein 12, ... (7 entities in total) |
| Functional Keywords | hdac, chromatin, cell cycle, transcription, gene regulation |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 3 |
| Total formula weight | 226788.05 |
| Authors | Wan, M.S.M.,Muhammad, R.,Koliopolous, M.G.,Alfieri, C. (deposition date: 2022-11-16, release date: 2023-05-10, Last modification date: 2023-05-17) |
| Primary citation | Wan, M.S.M.,Muhammad, R.,Koliopoulos, M.G.,Roumeliotis, T.I.,Choudhary, J.S.,Alfieri, C. Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex. Nat Commun, 14:2556-2556, 2023 Cited by PubMed: 37137925DOI: 10.1038/s41467-023-38276-0 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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