PDB: 257 件ウェブページステータス検索Chemie searchBIRD

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7M6L	High resolution structure of the membrane embedded skeletal muscle ryanodine receptor 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ... 著者 Melville, Z, Kim, K, Clarke, O.B, Marks, A.R. 登録日 2021-03-25 公開日 2021-08-18 最終更新日 2022-01-19 実験手法 ELECTRON MICROSCOPY (3.98 Å) 主引用文献 High-resolution structure of the membrane-embedded skeletal muscle ryanodine receptor. Structure, 30, 2022
7NSB	Supramolecular assembly module of yeast Chelator-GID SR4 E3 ubiquitin ligase 分子名称: Glucose-induced degradation protein 7, Glucose-induced degradation protein 8, Vacuolar import and degradation protein 30 著者 Chrustowicz, J, Sherpa, D, Prabu, J.R, Schulman, B.A. 登録日 2021-03-05 公開日 2021-05-05 最終更新日 2021-06-16 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme. Mol.Cell, 81, 2021
7NSC	Substrate receptor scaffolding module of human CTLH E3 ubiquitin ligase 分子名称: Glucose-induced degradation protein 4 homolog, Glucose-induced degradation protein 8 homolog, Isoform 2 of Armadillo repeat-containing protein 8, ... 著者 Chrustowicz, J, Sherpa, D, Prabu, J.R, Schulman, B.A. 登録日 2021-03-05 公開日 2021-05-05 最終更新日 2021-06-16 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme. Mol.Cell, 81, 2021
6UMA	Crystal structure of the TRIM7 B30.2 domain at 1.6 angstrom resolution 分子名称: E3 ubiquitin-protein ligase TRIM7, GLYCEROL, MALONATE ION 著者 Munoz Sosa, C.J, Carrizo, M.E. 登録日 2019-10-09 公開日 2021-04-14 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure and mutational analysis of the human TRIM7 B30.2 domain provide insights into the molecular basis of its binding to glycogenin-1. J.Biol.Chem., 296, 2021
6UMB	Crystal structure of TRIM7 B30.2 domain at 1.8 angstrom resolution 分子名称: BETA-MERCAPTOETHANOL, E3 ubiquitin-protein ligase TRIM7, MALONATE ION 著者 Munoz Sosa, C.J, Carrizo, M.E. 登録日 2019-10-09 公開日 2021-04-14 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure and mutational analysis of the human TRIM7 B30.2 domain provide insights into the molecular basis of its binding to glycogenin-1. J.Biol.Chem., 296, 2021
6W5N	Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class05) 分子名称: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... 著者 Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U. 登録日 2020-03-13 公開日 2021-03-31 最終更新日 2022-10-12 実験手法 ELECTRON MICROSCOPY (6 Å) 主引用文献 Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin. Nat Commun, 12, 2021
6W5M	Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class02) 分子名称: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... 著者 Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U. 登録日 2020-03-13 公開日 2021-03-31 最終更新日 2022-10-12 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin. Nat Commun, 12, 2021
6W5I	Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class01) 分子名称: DNA (147-MER), Histone H2A, Histone H2B 1.1, ... 著者 Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U. 登録日 2020-03-13 公開日 2021-03-31 最終更新日 2022-10-12 実験手法 ELECTRON MICROSCOPY (6.9 Å) 主引用文献 Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin. Nat Commun, 12, 2021
6SJH	Structure of the PRY-SPRY domain of human Trim16L/Trim70 分子名称: Tripartite motif-containing protein 16-like protein 著者 Mikkelsen, J.H, Andersen, C.B.F. 登録日 2019-08-13 公開日 2021-02-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of the PRY-SPRY domain of human Trim16L/Trim70 To Be Published
6LT9	The crystal structure of diamondback moth ryanodine receptor SPRY1 domain 分子名称: GLYCEROL, Ryanodine receptor 1, SODIUM ION 著者 Zhou, Y, Lin, L, Yuchi, Z. 登録日 2020-01-22 公開日 2021-01-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 The crystal structure of diamondback moth ryanodine receptor SPRY1 domain To Be Published
7B2S	Crystal structure of SPRY domain of TRIM9 分子名称: E3 ubiquitin-protein ligase TRIM9, SULFATE ION 著者 Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2020-11-27 公開日 2021-01-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of SPRY domain of TRIM9 To Be Published
7JL3	Cryo-EM structure of RIG-I:dsRNA filament in complex with RIPLET PrySpry domain (trimer) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ... 著者 Kato, K, Ahmad, S, Hur, S. 登録日 2020-07-29 公開日 2020-12-09 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases. Mol.Cell, 81, 2021
7JL0	Cryo-EM structure of MDA5-dsRNA in complex with TRIM65 PSpry domain (Monomer) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, MAGNESIUM ION, ... 著者 Kato, K, Ahmad, S, Hur, S. 登録日 2020-07-29 公開日 2020-12-09 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases. Mol.Cell, 81, 2021
7JL1	Cryo-EM structure of RIG-I:dsRNA in complex with RIPLET PrySpry domain (monomer) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ... 著者 Kato, K, Ahmad, S, Hur, S. 登録日 2020-07-29 公開日 2020-12-09 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases. Mol.Cell, 81, 2021
7JL4	Crystal structure of TRIM65 PSpry domain 分子名称: GLYCEROL, Tripartite motif-containing protein 65 著者 Kato, K, Ahmad, S, Hur, S. 登録日 2020-07-29 公開日 2020-12-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases. Mol.Cell, 81, 2021
7JL2	Cryo-EM structure of MDA5-dsRNA filament in complex with TRIM65 PSpry domain (Trimer) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, MAGNESIUM ION, ... 著者 Kato, K, Ahmad, S, Hur, S. 登録日 2020-07-29 公開日 2020-12-09 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases. Mol.Cell, 81, 2021
7CCB	Crystal structure of the SPRY domain-containing protein 7 (SPRY7) 分子名称: SPRY domain-containing protein 7 著者 Yang, J, Kuang, Z. 登録日 2020-06-16 公開日 2020-10-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Crystal structure of the SPRY domain-containing protein 7 reveals unique structural features. Biochem.Biophys.Res.Commun., 531, 2020
6M2W	Structure of RyR1 (Ca2+/Caffeine/ATP/CaM1234/CHL) 分子名称: 5-bromanyl-N-[4-chloranyl-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloranylpyridin-2-yl)pyrazole-3-carboxamide, ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, ... 著者 Ma, R, Haji-Ghassemi, O, Ma, D, Lin, L, Samurkas, A, Van Petegem, F, Yuchi, Z. 登録日 2020-03-01 公開日 2020-09-02 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis for diamide modulation of ryanodine receptor. Nat.Chem.Biol., 16, 2020
7CF9	Structure of RyR1 (Ca2+/CHL) 分子名称: 5-bromanyl-N-[4-chloranyl-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloranylpyridin-2-yl)pyrazole-3-carboxamide, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... 著者 Ma, R, Haji-Ghassemi, O, Ma, D, Lin, L, Samurkas, A, Van Petegem, F, Yuchi, Z. 登録日 2020-06-24 公開日 2020-09-02 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Structural basis for diamide modulation of ryanodine receptor. Nat.Chem.Biol., 16, 2020
6WOV	Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 wild type in complex with FKBP12.6 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION 著者 Iyer, K.A, Hu, Y, Nayak, A.R, Kurebayashi, N, Murayama, T, Samso, M. 登録日 2020-04-25 公開日 2020-08-05 最終更新日 2022-08-03 実験手法 ELECTRON MICROSCOPY (5.1 Å) 主引用文献 Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM. Sci Adv, 6, 2020
6WOU	Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 mutant R176Q in complex with FKBP12.6 in nanodisc 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION 著者 Iyer, K.A, Hu, Y, Kurebayashi, N, Murayama, T, Samso, M. 登録日 2020-04-25 公開日 2020-08-05 最終更新日 2022-08-03 実験手法 ELECTRON MICROSCOPY (3.27 Å) 主引用文献 Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM. Sci Adv, 6, 2020
6WOT	Cryo-EM structure of recombinant rabbit Ryanodine Receptor type 1 mutant R164C in complex with FKBP12.6 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION 著者 Iyer, K.A, Hu, Y, Kurebayashi, N, Murayama, T, Samso, M. 登録日 2020-04-25 公開日 2020-08-05 最終更新日 2022-08-03 実験手法 ELECTRON MICROSCOPY (3.54 Å) 主引用文献 Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM. Sci Adv, 6, 2020
7BRE	The crystal structure of MLL2 in complex with ASH2L and RBBP5 分子名称: Histone-lysine N-methyltransferase 2B, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Li, Y, Zhao, L, Chen, Y. 登録日 2020-03-28 公開日 2020-07-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.803 Å) 主引用文献 Crystal Structure of MLL2 Complex Guides the Identification of a Methylation Site on P53 Catalyzed by KMT2 Family Methyltransferases. Structure, 28, 2020
6KIM	Crystal structure of diamondback moth ryanodine receptor SPRY2 domain 分子名称: GLYCEROL, Ryanodine receptor 著者 Zhou, Y, Lin, L, Yuchi, Z. 登録日 2019-07-19 公開日 2020-07-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.057 Å) 主引用文献 Crystal structure of diamondback moth ryanodine receptor SPRY2 domain To Be Published
6KEY	Structural basis for the regulation of inducible nitric oxide synthase (iNOS) by the SPRY domain-containing SOCS box protein 2 (SPSB2) 分子名称: Nitric oxide synthase, inducible, SPRY domain-containing SOCS box protein 2 著者 Li, K, Kuang, Z. 登録日 2019-07-05 公開日 2020-07-01 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 Structural basis for the regulation of inducible nitric oxide synthase by the SPRY domain-containing SOCS box protein SPSB2, an E3 ubiquitin ligase. Nitric Oxide, 113-114, 2021

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