PDB: 1448 件ウェブページステータス検索Chemie searchBIRD

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4Q5E	Shigella Effector Kinase OspG bound to E2-Ub UbcH7-Ub Conjugate 分子名称: Polyubiquitin, Protein kinase OspG, Ubiquitin-conjugating enzyme E2 L3 著者 Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2014-04-16 公開日 2014-07-02 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (1.869 Å) 主引用文献 Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG. Structure, 22, 2014
4MM3	Crystal structure of SARS-CoV papain-like protease PLpro in complex with ubiquitin aldehyde 分子名称: Papain-like proteinase, Ubiquitin, ZINC ION 著者 Mesecar, A.D, Ratia, K. 登録日 2013-09-08 公開日 2014-07-02 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.752 Å) 主引用文献 Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating activity of SARS-CoV papain-like protease. Plos Pathog., 10, 2014
4V8P	T.thermophila 60S ribosomal subunit in complex with initiation factor 6. 分子名称: 26S RRNA, 5.8S RRNA, 5S RRNA, ... 著者 Klinge, S, Voigts-Hoffmann, F, Leibundgut, M, Arpagaus, S, Ban, N. 登録日 2011-09-14 公開日 2014-07-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.52 Å) 主引用文献 Crystal Structure of the Eukaryotic 60S Ribosomal Subunit in Complex with Initiation Factor 6. Science, 334, 2011
4V8Z	Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex 分子名称: 18S RIBOSOMAL RNA, 25S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN S0-A, ... 著者 Fernandez, I.S, Bai, X.C, Hussain, T, Kelley, A.C, Lorsch, J.R, Ramakrishnan, V, Scheres, S.H.W. 登録日 2013-07-20 公開日 2014-07-09 最終更新日 2023-03-01 実験手法 ELECTRON MICROSCOPY (6.6 Å) 主引用文献 Molecular architecture of a eukaryotic translational initiation complex. Science, 342, 2013
4V88	The structure of the eukaryotic ribosome at 3.0 A resolution. 分子名称: 18S RIBOSOMAL RNA, 18S rRNA, 25S rRNA, ... 著者 Ben-Shem, A, Garreau de Loubresse, N, Melnikov, S, Jenner, L, Yusupova, G, Yusupov, M. 登録日 2011-10-11 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structure of the eukaryotic ribosome at 3.0 angstrom resolution. Science, 334, 2011
4V8M	High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome 分子名称: 18S RRNA OF THE SMALL RIBOSOMAL SUBUNIT, 40S RIBOSOMAL PROTEIN S10, PUTATIVE, ... 著者 Hashem, Y, des Georges, A, Fu, J, Buss, S.N, Jossinet, F, Jobe, A, Zhang, Q, Liao, H.Y, Grassucci, R.A, Bajaj, C, Westhof, E, Madison-Antenucci, S, Frank, J. 登録日 2012-12-09 公開日 2014-07-09 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (5.57 Å) 主引用文献 High-Resolution Cryo-Electron Microscopy Structure of the Trypanosoma Brucei Ribosome. Nature, 494, 2013
4V8Y	Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex 分子名称: 18S RIBOSOMAL RNA, 25S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN S0-A, ... 著者 Fernandez, I.S, Bai, X.C, Hussain, T, Kelley, A.C, Lorsch, J.R, Ramakrishnan, V, Scheres, S.H.W. 登録日 2013-07-20 公開日 2014-07-09 最終更新日 2023-03-01 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Molecular architecture of a eukaryotic translational initiation complex. Science, 342, 2013
4V8T	Cryo-EM Structure of the 60S Ribosomal Subunit in Complex with Arx1 and Rei1 分子名称: 25S RIBOSOMAL RNA, 5.8S RIBOSOMAL RNA, 5S RIBOSOMAL RNA, ... 著者 Greber, B.J, Boehringer, D, Montellese, C, Ban, N. 登録日 2012-08-07 公開日 2014-07-09 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (8.1 Å) 主引用文献 Cryo-Em Structures of Arx1 and Maturation Factors Rei1 and Jjj1 Bound to the 60S Ribosomal Subunit Nat.Struct.Mol.Biol., 19, 2012
3J79	Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, large subunit 分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Wong, W, Bai, X.C, Brown, A, Fernandez, I.S, Hanssen, E, Condron, M, Tan, Y.H, Baum, J, Scheres, S.H.W. 登録日 2014-06-02 公開日 2014-07-16 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine. Elife, 3, 2014
4PYU	The conserved ubiquitin-like protein hub1 plays a critical role in splicing in human cells 分子名称: U4/U6.U5 tri-snRNP-associated protein 1, Ubiquitin-like protein 5 著者 Ammon, T, Mishra, S.K, Kowalska, K, Popowicz, G.M, Holak, T.A, Jentsch, S. 登録日 2014-03-28 公開日 2014-07-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The conserved ubiquitin-like protein Hub1 plays a critical role in splicing in human cells. J Mol Cell Biol, 6, 2014
4P4H	Caught-in-action signaling complex of RIG-I 2CARD domain and MAVS CARD domain 分子名称: Mitochondrial antiviral-signaling protein, Probable ATP-dependent RNA helicase DDX58, Ubiquitin-60S ribosomal protein L40 著者 Wu, B, Hur, S. 登録日 2014-03-12 公開日 2014-07-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Molecular Imprinting as a Signal-Activation Mechanism of the Viral RNA Sensor RIG-I. Mol.Cell, 55, 2014
3J78	Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class I - non-rotated ribosome with 2 tRNAs) 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... 著者 Svidritskiy, E, Brilot, A.F, Koh, C.S, Grigorieff, N, Korostelev, A.A. 登録日 2014-05-29 公開日 2014-08-06 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (6.3 Å) 主引用文献 Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations. Structure, 22, 2014
3J77	Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class II - rotated ribosome with 1 tRNA) 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... 著者 Svidritskiy, E, Brilot, A.F, Koh, C.S, Grigorieff, N, Korostelev, A.A. 登録日 2014-05-29 公開日 2014-08-06 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (6.2 Å) 主引用文献 Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations. Structure, 22, 2014
4UN2	Crystal structure of the UBA domain of Dsk2 in complex with Ubiquitin 分子名称: UBIQUITIN, UBIQUITIN DOMAIN-CONTAINING PROTEIN DSK2 著者 Michielssens, S, Peters, J.H, Ban, D, Pratihar, S, Seeliger, D, Sharma, M, Giller, K, Sabo, T.M, Becker, S, Lee, D, Griesinger, C, de Groot, B.L. 登録日 2014-05-23 公開日 2014-08-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 A Designed Conformational Shift to Control Protein Binding Specificity. Angew.Chem.Int.Ed.Engl., 53, 2014
2MBE	Backbone 1H and 15N Chemical Shift Assignments for the first domain of FAT10 分子名称: Ubiquitin D 著者 Wang, W, Lim, L, Qin, H. 登録日 2013-07-30 公開日 2014-08-27 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Disruption of FAT10-MAD2 binding inhibits tumor progression. Proc.Natl.Acad.Sci.USA, 111, 2014
3J7P	Structure of the 80S mammalian ribosome bound to eEF2 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... 著者 Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. 登録日 2014-08-01 公開日 2014-09-03 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution. Cell(Cambridge,Mass.), 157, 2014
3J7R	Structure of the translating mammalian ribosome-Sec61 complex 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... 著者 Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. 登録日 2014-08-01 公開日 2014-09-03 最終更新日 2019-10-30 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution. Cell(Cambridge,Mass.), 157, 2014
3J7O	Structure of the mammalian 60S ribosomal subunit 分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. 登録日 2014-08-01 公開日 2014-09-03 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution. Cell(Cambridge,Mass.), 157, 2014
3J7Q	Structure of the idle mammalian ribosome-Sec61 complex 分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. 登録日 2014-08-01 公開日 2014-09-03 最終更新日 2019-10-30 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution. Cell(Cambridge,Mass.), 157, 2014
4W9G	pVHL:EloB:EloC in complex with (2S,4R)-1-(3,3-dimethylbutanoyl)-4-hydroxy-N-(3-methyl-4-(thiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (ligand 6) 分子名称: (4R)-1-(3,3-dimethylbutanoyl)-4-hydroxy-N-[3-methyl-4-(1,3-thiazol-5-yl)benzyl]-L-prolinamide, Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2, ... 著者 Gadd, M.S, Soares, P, Galdeano, C, van Molle, I, Ciulli, A. 登録日 2014-08-27 公開日 2014-09-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure-Guided Design and Optimization of Small Molecules Targeting the Protein-Protein Interaction between the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities. J.Med.Chem., 57, 2014
4W9K	pVHL:EloB:EloC in complex with (2S,4R)-1-((S)-2-((S)-2-acetamido-3-phenylpropanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (ligand 14) 分子名称: N-acetyl-L-phenylalanyl-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide, Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2, ... 著者 Gadd, M.S, Galdeano, C, van Molle, I, Ciulli, A. 登録日 2014-08-27 公開日 2014-09-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-Guided Design and Optimization of Small Molecules Targeting the Protein-Protein Interaction between the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities. J.Med.Chem., 57, 2014
4W9I	pVHL:EloB:EloC in complex with (2S,4R)-1-((2S,4R)-1-acetyl-4-hydroxypyrrolidine-2-carbonyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (ligand 10) 分子名称: (4R)-1-acetyl-4-hydroxy-L-prolyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide, Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2, ... 著者 Gadd, M.S, Soares, P, Galdeano, C, van Molle, I, Ciulli, A. 登録日 2014-08-27 公開日 2014-09-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-Guided Design and Optimization of Small Molecules Targeting the Protein-Protein Interaction between the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities. J.Med.Chem., 57, 2014
4W9C	pVHL:EloB:EloC in complex with (2S,4R)-1-(3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(oxazol-5-yl)benzyl)pyrrolidine-2-carboxamide (ligand 2) 分子名称: (4R)-1-(3,3-dimethylbutanoyl)-4-hydroxy-N-[4-(1,3-oxazol-5-yl)benzyl]-L-prolinamide, Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2, ... 著者 Gadd, M.S, Hewitt, S, Galdeano, C, van Molle, I, Ciulli, A. 登録日 2014-08-27 公開日 2014-09-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-Guided Design and Optimization of Small Molecules Targeting the Protein-Protein Interaction between the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities. J.Med.Chem., 57, 2014
4W9D	pVHL:EloB:EloC in complex with (2S,4R)-1-(3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methyloxazol-5-yl)benzyl)pyrrolidine-2-carboxamide (ligand 3) 分子名称: (4R)-1-(3,3-dimethylbutanoyl)-4-hydroxy-N-[4-(4-methyl-1,3-oxazol-5-yl)benzyl]-L-prolinamide, Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2, ... 著者 Gadd, M.S, Hewitt, S, Galdeano, C, van Molle, I, Ciulli, A. 登録日 2014-08-27 公開日 2014-09-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-Guided Design and Optimization of Small Molecules Targeting the Protein-Protein Interaction between the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities. J.Med.Chem., 57, 2014
4W9H	pVHL:EloB:EloC in complex with (2S,4R)-1-((S)-2-acetamido-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (ligand 7) 分子名称: N-acetyl-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide, Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2, ... 著者 Gadd, M.S, Soares, P, Galdeano, C, van Molle, I, Ciulli, A. 登録日 2014-08-27 公開日 2014-09-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-Guided Design and Optimization of Small Molecules Targeting the Protein-Protein Interaction between the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities. J.Med.Chem., 57, 2014

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