4U48
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4RTD
| Escherichia coli alpha-2-macroglobulin activated by porcine elastase | 分子名称: | Uncharacterized lipoprotein YfhM | 著者 | Fyfe, C.D, Grinter, R, Roszak, A.W, Josts, I, Cogdell, R.J, Walker, D. | 登録日 | 2014-11-14 | 公開日 | 2015-07-15 | 最終更新日 | 2015-07-29 | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | 主引用文献 | Structure of protease-cleaved Escherichia coli alpha-2-macroglobulin reveals a putative mechanism of conformational activation for protease entrapment. Acta Crystallogr.,Sect.D, 71, 2015
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4LNV
| Crystal Structure of TEP1s | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Thioester-containing protein I | 著者 | Le, B.V, Williams, M, Logarajah, S, Baxter, R.H.G. | 登録日 | 2013-07-12 | 公開日 | 2013-07-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Molecular basis for genetic resistance of Anopheles gambiae to Plasmodium: structural analysis of TEP1 susceptible and resistant alleles. Plos Pathog., 8, 2012
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4E0S
| Crystal Structure of C5b-6 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C5, ... | 著者 | Aleshin, A.E, Stec, B, DiScipio, R, Liddington, R.C. | 登録日 | 2012-03-05 | 公開日 | 2012-04-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (4.21 Å) | 主引用文献 | Crystal structure of c5b-6 suggests structural basis for priming assembly of the membrane attack complex. J.Biol.Chem., 287, 2012
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4D94
| Crystal Structure of TEP1r | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Le, B.V, Williams, M, Logarajah, S, Baxter, R.H.G. | 登録日 | 2012-01-11 | 公開日 | 2012-10-17 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Molecular Basis for Genetic Resistance of Anopheles gambiae to Plasmodium: Structural Analysis of TEP1 Susceptible and Resistant Alleles. Plos Pathog., 8, 2012
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4A5W
| Crystal structure of C5b6 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C5, ... | 著者 | Hadders, M.A, Bubeck, D, Forneris, F, Pangburn, M, Llorca, O, Lea, S.M, Gros, P. | 登録日 | 2011-10-28 | 公開日 | 2012-03-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5B6 and Sc5B9. Cell Rep., 1, 2012
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3T4A
| Structure of a truncated form of Staphylococcal Complement Inhibitor B bound to human C3c at 3.4 Angstrom resolution | 分子名称: | Complement C3 beta chain, Complement C3c alpha' chain fragment 1, Complement C3c alpha' chain fragment 2, ... | 著者 | Garcia, B.L, Geisbrecht, B.V, Summers, B.J. | 登録日 | 2011-07-25 | 公開日 | 2011-11-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family. J.Biol.Chem., 287, 2012
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3PVM
| Structure of Complement C5 in Complex with CVF | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, Complement C5 | 著者 | Laursen, N.S, Andersen, K.R, Braren, I, Sottrup-Jensen, L, Spillner, E, Andersen, G.R. | 登録日 | 2010-12-07 | 公開日 | 2011-01-19 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | 主引用文献 | Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex. Embo J., 30, 2011
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3PRX
| Structure of Complement C5 in Complex with CVF and SSL7 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, ... | 著者 | Laursen, N.S, Andersen, G.R, Sottrup-Jensen, L, Andersen, K.R, Spillner, E, Braren, I. | 登録日 | 2010-11-30 | 公開日 | 2011-01-19 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | 主引用文献 | Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex. Embo J., 30, 2011
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3OHX
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3NMS
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3L5N
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3L3O
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3KM9
| Structure of complement C5 in complex with the C-terminal beta-grasp domain of SSL7 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ... | 著者 | Laursen, N.S, Gordon, N, Hermans, S, Lorenz, N, Jackson, N, Wines, B, Spillner, E, Christensen, J.B, Jensen, M, Fredslund, F, Bjerre, M, Sottrup-Jensen, L, Fraser, J.D, Andersen, G.R. | 登録日 | 2009-11-10 | 公開日 | 2009-12-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus Proc.Natl.Acad.Sci.USA, 107, 2010
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3KLS
| Structure of complement C5 in complex with SSL7 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ... | 著者 | Laursen, N.S, Gordon, N, Hermans, S, Lorenz, N, Jackson, N, Wines, B, Spillner, E, Christensen, J.B, Jensen, M, Fredslund, F, Bjerre, M, Sottrup-Jensen, L, Fraser, J.D, Andersen, G.R. | 登録日 | 2009-11-09 | 公開日 | 2009-11-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus Proc.Natl.Acad.Sci.USA, 107, 2010
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3HS0
| Cobra Venom Factor (CVF) in complex with human factor B | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, ... | 著者 | Janssen, B.J.C, Gomes, L, Koning, R.I, Svergun, D.I, Koster, A.J, Fritzinger, D.C, Vogel, C.-W, Gros, P. | 登録日 | 2009-06-10 | 公開日 | 2009-07-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex Embo J., 28, 2009
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3HRZ
| Cobra Venom Factor (CVF) in complex with human factor B | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, ... | 著者 | Janssen, B.J.C, Gomes, L, Koning, R.I, Svergun, D.I, Koster, A.J, Fritzinger, D.C, Vogel, C.-W, Gros, P. | 登録日 | 2009-06-10 | 公開日 | 2009-07-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex Embo J., 28, 2009
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3G6J
| C3b in complex with a C3b specific Fab | 分子名称: | CALCIUM ION, Complement C3 alpha chain, Complement C3 beta chain, ... | 著者 | Wiesmann, C. | 登録日 | 2009-02-06 | 公開日 | 2009-03-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural and Functional Analysis of a C3b-specific Antibody That Selectively Inhibits the Alternative Pathway of Complement J.Biol.Chem., 284, 2009
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3FRP
| Crystal Structure of Cobra Venom Factor, a Co-factor for C3- and C5 convertase CVFBb | 分子名称: | CALCIUM ION, Cobra venom factor alpha chain, Cobra venom factor beta chain, ... | 著者 | Krishnan, V, Narayana, S.V.L. | 登録日 | 2009-01-08 | 公開日 | 2009-04-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | The Crystal Structure of Cobra Venom Factor, a Cofactor for C3- and C5-Convertase CVFBb. Structure, 17, 2009
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3CU7
| Human Complement Component 5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ... | 著者 | Fredslund, F, Andersen, G.R. | 登録日 | 2008-04-16 | 公開日 | 2008-06-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.105 Å) | 主引用文献 | Structure of and influence of a tick complement inhibitor on human complement component 5 Nat.Immunol., 9, 2008
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2XWJ
| Crystal Structure of Complement C3b in Complex with Factor B | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 ALPHA CHAIN, COMPLEMENT C3 BETA CHAIN, ... | 著者 | Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P. | 登録日 | 2010-11-04 | 公開日 | 2011-01-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation. Science, 330, 2010
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2XWB
| Crystal Structure of Complement C3b in complex with Factors B and D | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3B ALPHA' CHAIN, ... | 著者 | Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P. | 登録日 | 2010-11-01 | 公開日 | 2011-01-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | 主引用文献 | Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation. Science, 330, 2010
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2WIN
| C3 convertase (C3bBb) stabilized by SCIN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 BETA CHAIN, ... | 著者 | Wu, J, Janssen, B.J, Gros, P. | 登録日 | 2009-05-13 | 公開日 | 2009-06-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor. Nat. Immunol., 10, 2009
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2WII
| Complement C3b in complex with factor H domains 1-4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C3 BETA CHAIN, ... | 著者 | Wu, J, Janssen, B.J.C, Gros, P. | 登録日 | 2009-05-12 | 公開日 | 2009-06-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of complement fragment C3b-factor H and implications for host protection by complement regulators. Nat. Immunol., 10, 2009
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2QKI
| Human C3c in complex with the inhibitor compstatin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, Complement C3, ... | 著者 | Janssen, B.J.C, Halff, E.F, Lambris, J.D, Gros, P. | 登録日 | 2007-07-11 | 公開日 | 2007-08-14 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition. J.Biol.Chem., 282, 2007
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